As deposits build up under the eye, the retina bends with macular degeneration

Wet macular degeneration affects 10%-15% of those with macular degeneration

This form of molecular degeneration refers to when excess blood vessels form in the back of the eye and damage the macula. If someone with this condition looks at straight lines, they will typically appear wavy or crooked.

Drusen are bumps under the retina that distort the vision of most macular degeneration patients

These yellow deposits are made up of proteins and lipids and come in a variety of sizes. They're common in people aged 50 and older, but amassing many of them is often a symptom of age-related macular degeneration—the most prevalent type of macular degeneration.

The macula is a small area in the center of the retina

This part of the eye—roughly the bullseye of the back of the eye—is responsible for processing the central vision of the eye. Degradation of the macula, formally called macular degeneration, leads to symptoms including blurred vision, the need for brighter lighting, and difficulty recognizing faces. The condition doesn't affect peripheral vision, but if you lose central vision, you can still be considered blind.

Age-related macular degeneration is the primary cause of blindness in older Americans

Around 20 million Americans suffer from macular degeneration, and it's the leading cause of blindness in older Americans. Risk factors for age-related macular degeneration include aging, genetics, smoking, hypertension, obesity, and diet.

LIghter-colored eyes have heightened risks for macular degeneration

People with blue eyes appear to be at elevated risk of developing the disorder, perhaps because more light can penetrate their eyes. But the most significant modifiable factor heightening the risk for macular degeneration is smoking.

Vitamins can slow macular degeneration

Research published in 2022 affirmed that vitamin formulations containing vitamins C and E, copper, zinc, lutein, and zeaxanthin—but no beta carotene—can enhance eye health and slow the progression of macular degeneration.

Photodynamic therapy is one current treatment for age-related macular degeneration

This laser-based treatment is used on advanced "wet" age-related macular degeneration patients, but it's now used less often than in the past because there are newer injection-based drugs to decrease abnormal blood vessel growth.

Watch patient stories describing life with macular degeneration

This video series features patients discussing their experiences with the disorder, family members describing caregiving, and other insights about the disease.

There are more than 1,400 listed clinical trials for macular degeneration

The US database of clinical trials listed more than 1,400 macular degeneration trials in early 2026. That doesn't mean every trial is recruiting, but it does indicate there is significant interest in this medical condition.

In a first, eye prosthesis has restored sight to macular generation patients

In a clinical trial, 27 of 32 participants with advanced macular degeneration regained enough vision to read books, food labels, and subway signs about a year after receiving a prosthetic retina device. This is the first device to restore functional vision to patients with incurable vision loss, though in this case they can only see in black and white, with no shades in between.

Changes in vision or eye pain can be early MS symptoms

This occurs due to myelin degradation around the optic nerve, impairing its ability to transmit visual information to the brain. Individuals may especially experience eye symptoms after exercising or taking a hot shower because boosted body temperatures slow down nerve function in nerves already damaged by MS.

Corrective vision technologies rely on the bending of light waves

When focusing on an object, muscles change the shape of the lens, which refracts incoming light such that it focuses at the retina. If the cornea is unable to bend light correctly, lenses or contact lenses can provide supplemental refraction to ensure a focused image is produced.

Why vascular dementia develops

This type of dementia, the second most common form after Alzheimer's, develops due to microscopic bleeds and blood vessel blockages in the brain. The condition isn't curable but medications to help with blood clotting and high blood pressure are part of a suite of interventions designed to minimize damage to the brain.

Diabetes has downstream effects on the heart, eyes, kidneys, and more

High blood sugar levels in untreated diabetes roughen artery walls, increasing plaque buildup, heart disease, and high blood pressure risk. High levels also cause acid to build up in the bloodstream, potentially making the brain swell, the lungs fill with fluid, and the heart to beat arrhythmically—all fatal complications.

Usher Syndrome, a rare genetic disorder, causes progressive hearing and vision loss

People with one of the subtypes of this condition have a genetic mutation that starves cells in the inner ear and the retina of proteins required for detecting sound and light. Gene therapy in animals has seemed like a promising treatment for the condition.

One theory claims the retinae of SAD patients may fail to adjust to less light in winter

Most people’s eyes become more sensitive to light in the winter months, but some do not. This failure to adjust causes ripple effects on those individuals’ biological clocks. This Ted-ED video provides a clear, brief, narrative explanation of the condition in six minutes.

Ménière's disease is a long-term, inner ear disorder that causes vertigo

This severe vertigo-causing disorder may involve long and recurrent episodes of vertigo. Symptoms of this disease include balance issues and hearing loss, tinnitus, and a feeling of fullness in the ear. It typically affects only one ear and is linked to a buildup of excess fluid in the inner ear.

Cellular aging and deterioration leads to tissue (and overall) aging

Cells are the building blocks of life, forming tissues and organs that keep our bodies working. As we age, cellular changes have progressive consequences on both the structure and function of our organs. This article examines this complex relationship as it relates to the incremental changes associated with aging.

Leprosy affects the skin, eyes, and upper respiratory tract

Untreated, the disease can lead to permanent nerve damage and the loss of sensation in arms, legs, and other extremities. The exact form of transmission remains unclear, but scientists suspect it is spread via respiratory droplets over a prolonged period. (Warning: Graphic content, including photos of deformities.)

Fear or disgust related to clusters of holes and cracks, called trypophobia, may stem from evolutionary processes to help us avoid pathogens.

What sleep loss does to the brain

Proteins in the brain perform various critical functions, such as helping neurotransmitters function or enabling electrical activity in the organ. These proteins must fold in specific ways to perform their duties, similar to paper airplanes. Sleep deprivation contributes to the gathering of misfolded proteins that aren't shaped correctly for their roles and so accumulate in undesired spaces, such as in the gaps between neurons.

Fear or disgust related to clusters of holes and cracks, called trypophobia, may stem from evolutionary processes to help us avoid pathogens

This type of extreme reaction to harmless holes, dots, cracks, and seed collections can be debilitating for those who have it, but it is not an officially recognized disorder in the DSM-5.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

When experiencing turbulence, fluid elements undergo stretching and folding

Simulations show patches of fluid particles, such as splashes of milk, bend under turbulent flow, creating curvature that grows linearly then exponentially. This accelerated deformation enhances folding and mixing faster than other methods, such as stirring or beating.

Rheumatoid arthritis occurs when the immune system attacks cells within joints

Rheumatoid arthritis is a specific type of arthritis that occurs when the body's immune system attacks normal cells within the connective tissues of the joint and degrades them. This sets off a painful cycle of inflammation and joint destruction that often requires lifelong medication to control.

Tattoos remain visible on your skin thanks to immune cells called macrophages

Tropical cyclone formation require warm water and limited vertical wind shear

Ocean temperatures above 27 degrees Celsius fuel rising, moist air, which releases energy through heat as water vapor condenses into clouds. Significant changes in wind speed with height can spread out these upflows, preventing the eventual formation of a central column known as the eye.

For every $100 you deposit, your bank puts a few cents in the FDIC insurance fund

This is a result of the 1933 Banking Act that established the Federal Deposit Insurance Fund. The law sought to prevent bank runs like those that decimated the banking industry amid the Great Crash and subsequent major depression. Today, individual depositors are insured up to $250K at each bank where they have an account.

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

Stars appear to twinkle because turbulence in the motion of molecules in Earth's atmosphere causes light to bend and wiggle rapidly on its way to the surface—a phenomenon called scintillation.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

Some coin denominations have ridges etched on their sides, partly to prevent counterfeiting, in a practice called 'reeding.'

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Watch how deep-sea mining equipment collects and processes polymetallic nodules—metal-rich, potato-shaped rocks—from the ocean floor and creates environmentally damaging plumes of sediments.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

Volcanoes 'die' when their supply of magma runs out, if they are shifted away from their underlying magma reservoir, or if they get clogged by collapsing or their magma cooling back into rock.

Hedge funds, the private investment firms that trade a wide swath of financial assets, make money by imposing steep fees on investors and from the fund's investment performance.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

See 33 images that became central to huge scandals, including a young Charles and Camilla, Michael Jackson's baby on a hotel balcony, and Hugh Grant's mugshot.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

Poison ivy is in the same family as mangoes, cashews, and pistachios—and they all produce oily urushiol in their raw, unprocessed state—but they are typically prepared in ways to avoid causing human discomfort.

Dorothy's famous entrance into Oz in 'The Wizard of Oz' relied on analog tricks, including a body double and sepia-toned paint, as much as it did on technology

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.

While El Niño moves warm Pacific Ocean waters east along the equator, La Niña moves them west, shifting where rainfall will become more common for months.

The Ramones' 'Pet Sematary,' the theme song for the Stephen King novel of the same name, was written while the band was admiring the writer's collection of horror memorabilia.