A super-sniffer smelled her husband's Parkinson's disease years ahead of symptoms

Dogs' disease-sniffing skills were first identified in 1989

This capability, reported in the medical journal The Lancet, was discovered when a dog reportedly detected cancer in its handler. The dog repeatedly focused on a spot on the owner's leg where a malignant melanoma lesion was later found, helping lead to an early diagnosis.

Smell is a robust memory cue for individuals with Alzheimer's disease

Odor is more effective than both visual and verbal cues for triggering autobiographical recall in Alzheimer's disease, according to 2021 research.

A stand-in 'nose' may help people with anosmia to smell certain odors

In a 2025 paper, researchers reported they'd created a proof-of-concept device that bypasses typical olfactory pathways and instead exploits an alternative—the trigeminal nerve in the nose—to detect a few strong scents. The nerve typically helps detect the temperature of inhaled air or the presence of irritants. (Some users may experience a paywall.)

Hereditary hyperosmia is the official term for being a super-smeller

Some sniffers with this rare trait may be more sensitive to pleasant smells, while others may be more attuned to unpleasant scents. Some research suggests that certain genetic mutations are associated with a heightened sense of smell.

Dogs smell a lot of stuff we can't, including bed bugs and chemicals in electronic devices

In addition to identifying medical smells and tiny insects like bed bugs, dogs can also detect electronic storage devices. These tools often contain triphenylphosphine oxide, a chemical used to prevent overheating.

Humans can track smells on the ground quite well—our ability to crawl is a limiting factor

As part of a scientific bet, neurobiology researchers dragged a chocolate bar across the grass and sought to see if a human could track it—she could. This led to a more in-depth experiment on human olfactory capabilities and behavior when other senses were blocked.

Heightened sense of smell during pregnancy is not yet well understood

Boosted smell powers and strong reactions to them are often reported beginning around the six-week mark of pregnancy. Researchers say hormonal changes likely play a role, but the change remains poorly understood.

Roughly 15 of every 1,000 people in the US have smell disorders

Anosmia is a lack of a sense of smell. It can be present at birth, related to diseases including Parkinson's, Alzheimer's, and COVID-19, or have unknown causes.

Typhoid smells like freshly baked brown bread

Certain ailments are associated with documented scents, including diabetes, Parkinson's disease, and typhoid. The skin of people with yellow fever, for example, can smell like a "butcher shop."

Genetic blood test offers an estimated clock on when Alzheimer's symptoms may appear

The 2026 research finding from researchers at Washington University School of Medicine in St. Louis—if validated in broader populations—suggests that an already available blood test could estimate when Alzheimer's symptoms may begin within a margin of several years. The test detects a protein called p-tau217 found in blood plasma and the researchers incorporated the findings from that blood test into a statistical model to come up with the symptom timeline predictions.

Examining self-diagnosed synesthesia

A growing number of people on social media claim to have a perceptual condition that lets them smell colors, see music, or taste sounds. But do they really?

A 'fishy' scent does lead to mistrust

In experiments where people were exposed to a literal fishy smell they were less willing to cooperate with others in economic games requiring trust, but that wasn't the case when they were exposed to another bad odor—the smell of flatulence.

'Sweat dating' is a dating approach where partners specifically select by body odor

With dedicated events in major cities around the world, "sweat dating" offers people the chance to judge if a potential partner's smell is a match. Participants show up for an event, do calisthenics, wipe themselves with a cotton pad, and then place the smelly pad in a numbered jar for potential partners to sniff.

A man with organ failure used AI to speed discovery of his miracle drug

David Fajgenbaum had a few months to live after a diagnosis with a rare form of Castleman's disease. By studying his blood, medical records, and broader literature, he was able to identify the cause of his condition and a treatment. He's been in total relapse for ten years.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Scientists seeking gut insights are attaching flatulence sensors to volunteers' underwear

This fart-tracking device detects gas generated in the gut, providing insights about gut microbial activity. The underwear sensors measure a component of what is technically called flatus—digestive system gas.

Pineapple research helped scientists solve Los Angeles' smog mystery

In the 1950s, chemist Arie Haagen-Smit applied methods he'd used studying pineapple plant chemistry to smog-filled air—discovering that sunlight reacting with car exhaust produced photochemical smog from hydrocarbons and nitrogen oxides, not factory smoke.

Health problems are being misdiagnosed as perimenopause symptoms

Symptoms of menopause and perimenopause (the premenopause period) can be varied enough that clinicians dismiss them in patients in their mid-30s and onward as just a symptom of hormone level change. In this story, a woman's itching was dismissed as a hormonal change, but after two years and 11 separate doctor consultations, was diagnosed as cancer. (Some users may experience a paywall.)

Alzheimer's as a family disease: When children become "parents"

Kitty Eisele's 81-year-old dad went missing while on a snowy, four-hour drive from Minneapolis to Iowa City. It was the first emergency that spelled out the danger of her dad's dementia diagnosis—and captures how Alzheimer’s impacts entire families, with the influx of responsibility that comes with caregiving.

Diagnosis as an adult can have huge benefits, including helping someone with ASD to feel real

This first-person account of a woman diagnosed with autism at age 31 covers her experience of why it was useful for her to receive her diagnosis as an adult and how it helped her to understand her life and her feelings of 'being an imposter.'

See how antidepressants were discovered

The decadeslong journey to the three major types of antidepressants began with medications designed to treat other maladies. Watch to learn more about how attempts to treat tuberculosis and blood pressure disorders led to new insights about neural chemistry and mood.

Scientists used mass spectrometry to determine the materials in a 1690 painting

Previously used to map the distribution of molecules on biological tissue samples, researchers combined the technique with machine learning to uncover six layers of pigments, binders, and a thin gold leaf layer within *The Marriage of the Virgin*, from a collection in the Metropolitan Museum of Art. The technique may help identify and track artists' material use to learn about pieces of unknown provenance. (Some readers may experience a paywall.)

Women's wartime suit features silk dyed with CRISPR-modified bacteria

Anna Dumitriu's bioart piece was created to commemorate the 75th anniversary of the first use of penicillin in a human patient and intends to raise awareness about the rapid development of antibiotic-resistant pathogens by using bacteria that have essentially been transformed into their pre-antibiotic era state.

Fear (and stress) can be contagious via pheromones secreted by the body

While seeing someone else in a panicked state may induce a stress response, researchers have found stress can be literally contagious—chemicals contained in sweat and other secretions can trigger stress hormone release in others. Theories suggest this feature is an evolutionary adaptation to protect groups from danger.

Rodent evidence is mounting that dysfunctional mitochondria may be a cause of Parkinson's

Though researchers have long observed mitochondrial malfunction in Parkinson's patients, it has remained unclear whether faulty mitochondria cause the disease or are casualties of it. Rodent research published in 2025 adds further weight to the idea that it's causative.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Managing an employee with a terminal illness

Managing an employee with a terminal illness might be a reality at some point, requiring a balance of compassion and strategic action. This article provides tips for best practices on managing the situation, such as adapting the work environment to the employee's needs (think: giving them flexible hours or the option to work remotely), involving them in decisions about any adjustments to their role, and more. Find out other things to consider here.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

When a Paris department store hesitated to sell Estée Lauder's perfume, she 'accidentally' broke a bottle, causing the smell to spread throughout the store and shoppers to start asking to buy the scent.

Scientists testing how climate change affects plants found, in a years-long simulation study, that poison ivy grew 70% faster with the resulting extra carbon dioxide.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

The story of Dollree Mapp, whose legal challenge over her 1957 conviction for possessing "obscene material" led to a major strengthening of the Fourth Amendment

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Explore the archaeological treasures of Pompeii, the city buried under volcanic ash when Mount Vesuvius erupted in 79 CE.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Salvador Dalí believed he was his own dead brother, who had died nine months before he was born

English mathematician Ada Lovelace wrote the first computer algorithm a century before computers existed and hypothesized that computing devices would one day be able to compose music—foreseeing the generative AI systems of today.

Search a massive database of over 4 decades of clues from the TV quiz show 'Jeopardy!'

'Silent' fireworks have gained more interest in recent years as a quieter celebratory option.

Hear 50 years of iconic hip-hop samples, the genre's foundational looped tracks

Comedy legend Catherine O'Hara, star of 'Schitt's Creek' and 'Home Alone,' quit 'Saturday Night Live' after just one week to return to her old job.