A step-by-step overview of the IVF process

IVF procedures fertilize eggs outside the body in a laboratory dish

In vitro fertilization is a complex and expensive set of procedures that potential parents dealing with infertility or genetic disorders may turn to when other methods are unavailable. IVF births account for 2% to 3% of all live births in the US annually.

Follow an IVF procedure from lab to transplant

What happens once eggs are harvested from an ovary? How does an embryo form within a petri dish? This detailed video offers a glimpse of the transformations eggs experience as women age, and how sperm are injected into eggs in some forms of IVF treatment.

Explore this interactive visualization of the IVF journey as a parent or child

This step-by-step graphic takes the viewer through different challenges and stages of the IVF journey, from a parent's and a child's perspective, including a parent's struggle when other families become pregnant around them, even as IVF is not working for their family.

Calculate your chance of success for IVF treatments

The efficacy of in vitro fertilization procedures varies widely based on age, health history, genetics, and more. This CDC calculator provides an estimate of success rates based on your personal information, relying on thousands of reported outcomes across the US.

IVF was long considered controversial and ethically dubious

In spite of its wide acceptance as a form of reproductive assistance today, and its role in helping millions of people have children, in vitro fertilization was once considered a controversial threat to society. One magazine went as far as to describe the procedure as "the biggest threat since the atom bomb."

Scientific advances are unlocking a wide range of alternatives to IVF

From refined artificial insemination and microsurgical sperm extraction to experimental uterine transplants, scientific innovation is rapidly advancing potential fertilization technologies. But they come along with costly trials, some ethical dilemmas, regulatory issues, and more.

The first successful IVF pregnancy was in the United Kingdom in 1978

Gynecologist Patrick Steptoe and his collaborator Robert Edwards, a biologist, attempted to fertilize a human egg cell in a petri dish 101 times before finally succeeding. This resulted in the birth of Louise Brown—at the time referred to as a "test tube" baby—in 1978, who was born into the spotlight.

In vitro gametogenesis: using induced stem cells to fertilize eggs

Using stem cells from skin and mouth cells could save hopeful parents time and money and spare egg donors from significant amounts of discomfort throughout the process. There are potential consequences, not just for infertility treatment, but for the ability to create customized cells of any type.

The average number of IVF cycles before a viable pregnancy is 2.5

Health insurance often does not cover IVF treatment, and Medicaid coverage for fertility services differs by state. As a result, the cost of IVF is often unrealistic for low-income families.

How women grow tiny humans inside of them

Pregnancy is a complex biological journey, lasting about 40 weeks. When a sperm fertilizes an egg, that event triggers intricate cellular and hormonal processes, driven by hardwired cellular instructions, which lead to cell division, differentiation, and development—ultimately culminating in the birth of a baby.

View an illustrative journey of sperm cells navigating toward fertilization

In this series of comic-style panels, a "fellowship" of sperm cells travels through fictionalized versions of reproductive anatomy on their way to an egg cell. Each panel includes informative commentary on each step of the adventure, with research insights provided by a reproductive biologist, a biomedical scientist, and an andrologist.

'Artificial embryos': The hidden steps in forming a spine

Somitogenesis is the process by which segmented body structures like vertebrae form in embryos. While the process is well understood in animals like mice or zebrafish it is difficult to study in humans. But now, researchers have created a model of somitogenesis, using pluripotent stem cells, called an axioloid.

There are 6 essential steps in cheesemaking

The six basic steps that are required to turn milk into cheese start with acidification and end with ripening (aka aging). This guide explains what happens at each step and how it contributes to the finished product.

How the body produces urine

Things seem so simple when nature calls. But, how does the body actually produce the urine we so regularly and thoughtlessly expel? This detailed, comprehensive animation walks viewers through every step with precise illustrations, from the kidney's filters (known as nephrons) to the direct nerve connecting the bladder to the brain. See how the body does it here.

How do you sequence a genome?

If the genome is made up of microscopic chromosomes, how do scientists actually sequence it? Here's a 5-minute video explaining one of the most common processes.

A step-by-step guide to the plastic recycling process

Everything you wanted to know about how plastic is recycled, the companies that collect and recycle plastic, where you can recycle, and much more.

Engineer explains VR at five levels of complexity

While its possible to grab a virtual reality headset and hop into an immersive world with little effort, a significant amount of technical and biological science has gone into creating the effect of a 3D world. This video breaks down the technology in five layers of increasing complexity.

A guide to the homebuying process

From searching for the home itself to writing an offer letter to closing on the home, there are specific steps involved in becoming a homeowner. This checklist from a Tennessee real estate broker provides a visual outlining the basic steps of the process.

An initial public offering or 'IPO' is the process of a private company becoming public by putting shares of the company on the stock market for purchase.

Learn how to build your own vivarium

Creating a self-contained habitat for plants and microscopic animals requires a careful balance of organisms that maintain a cycle of water, nutrients, and other chemicals throughout. Bottlenecks in these cycles are mitigated through careful construction, such as incorporating a drainage layer to effectively manage water.

Watch a tour of a battery manufacturing gigafactory

Inside Contemporary Amperex Technology Limited's facility, China's largest EV battery manufacturer uses slurry mixing, "jelly rolling," electrolyte injection, and other techniques and equipment to transform raw metals such as lithium and magnesium into approximately 2.2 million electrochemical cells daily.

See the differences between the Wegovy pill and injection

Examine this chart that compares and contrasts the oral and injectable Wegovy formulations. The differences include how they are absorbed by the body (through the digestive tract versus subcutaneously), their dosages, and the required timing (the pill is taken daily and has specialized timing requirements, while the injected form is administered once a week). Importantly, the pill form is also approved to treat fewer conditions.

An initial public offering is how a private company becomes public

This milestone requires plenty of preparation, starting with the SEC's S-1 registration, revealing key details about the company's finances and strategy. Investment bankers set valuations, secure long-term investors, and finalize share pricing before the public launch. IPOs provide companies with significant capital, but also demand transparency and invite public scrutiny.

What is vaccination? The World Health Org explains

Read up on the basics of vaccinations with this 101 from the World Health Organization, the public health arm of the United Nations.

Who’s who at the Vatican?

The Vatican is a massive organization whose processes and positions can appear impossibly dense to the common public. But, as this explainer from a University of Dayton professor makes clear, the Catholic Church's bureaucracy functions much like similarly-sized companies and universities. While the processes might still seem unnecessarily complex after reading, you'll at least be able to trace the org chart from the Pope on down.

How starting a union works

Starting a union within a workplace is a long, complicated process. There are many steps to take depending on how management reacts to each decision workers make during the proceedings. If you’re interested in helping your workplace unionize—or curious about what the journey to unionization looks like—this video can help.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Explore what it's like inside a patient isolation unit, used in situations such as treating a patient or suspected patient with Ebola.

Watch this video that uses Lego bricks to explain how venture capital works.

Coral polyps reproduce via broadcast spawning, where entire reefs simultaneously release reproductive cells for about one hour, once a year.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

How fusion—which releases energy when two lighter atoms combine to form a heavier atom—differs from fission

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.

Use this tool to calculate the dollar value of your parental mental load, from meal planning to coordinating after-school care, then see resources that help generate solutions.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Explore the known asteroids, comets, and spacecraft involved in asteroid studies within our solar system with 'Eyes on Asteroids,' a 3D visualization from NASA.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

The history of many kitchen appliances involves unexpected discoveries and applications, including wartime radar turned hamster defroster and replacing an 'ice king' with heat-stealing boxes.

Take a 3D tour of the Hajj, Islam's annual pilgrimage to Mecca, undertaken by more than 1.5 million Muslims each year.

Explore the archaeological treasures of Pompeii, the city buried under volcanic ash when Mount Vesuvius erupted in 79 CE.

Long before Major League Baseball began allowing instant replay for balls and strikes, an umpire reluctantly used the technology to determine whether a hit was a home run, a move that inadvertently ushered in a new era for the sport.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

Dorothy's famous entrance into Oz in 'The Wizard of Oz' relied on analog tricks, including a body double and sepia-toned paint, as much as it did on technology

This poison ivy knowledge quiz—accompanied by photos of the plant's varied forms—may help you identify this common rash-inducing growth.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

A century of Billboard issues documenting the evolution of popular music.