Why we don't have an answer for the common cold

Environmental conditions, shifting immunity, and viral strain could help explain 2025 spike

The surge in HFMD in the summer and early fall of 2025 in the mid-Atlantic could be the result of a confluence of factors, including a more virulent strain of disease-causing virus, good environmental conditions for the virus to spread—hot, humd—and a potential immunity gap among kids due to milder HFMD outbreaks the previous year.

The flu is a contagious respiratory illness caused by influenza viruses

Unlike the common cold, influenza attacks suddenly with fever, body aches, and fatigue. Seasonal strains circulate worldwide, infecting up to a billion people each year and causing hundreds of thousands of deaths despite vaccines and treatments.

Since 1600, the longest stretch without an outbreak that killed 10,000 was four years

We think of pandemics as unlikely events, but disease outbreaks are surprisingly common. Over the past 400 years, the longest stretch without an outbreak that killed at least 10,000 people was just four years. The next pandemic can't be precisely known, so experts and policymakers focus on preparation.

If you have a cold, the body produces excess mucus to trap germs

This process clogs up narrowed nasal airways, which results in congestion. This process is often accompanied or triggered by swelling of blood vessels in the nose.

How the 1918 pandemic spurred developments in virology and vaccines

This article provides an in-depth historical account of the 1918 Spanish Flu pandemic, including its impact on the global population and how its occurrence spurred significant advancements in the study of viruses—laying the groundwork for the...

Why some people have allergies

Why do some people have allergies while others don’t? One theory suggests allergies are a relic of our evolutionary past. Our immune system, once primed to fight parasites, now mistakes harmless substances for threats.

What are universal vaccines?

As viruses mutate and develop, vaccines have to adapt, leading to regular recommended injections like flu shots. Researchers are working to develop universal vaccines that aim to protect against multiple virus variants if not entire virus families. These vaccines work by creating broadly neutralizing antibodies (bnAbs) that target aspects of viruses that don't typically mutate and are integral to the virus' survival.

Measles is one of the most contagious preventable diseases

The virus’s ability to persist in the air for up to two hours means an infected person could enter a room, leave, and two hours later infect someone else entering the room. Its location in the body’s upper respiratory tract also makes it easy for viral particles to be sneezed or coughed into the air.

Explore 3D models of some of the most dangerous viruses

Everyone has come in contact with common viruses—typically something like influenza (the common flu)—but sometimes they encounter more dangerous strains. While we're familiar with the symptoms that manifest, it wasn't until the advent of advanced microscopy that scientists could pin down the exact structure and behavior of various viruses.

Loss of sense of smell is a common symptom of COVID-19 infection

In 2020, researchers discovered why this occurs. The virus that causes this infection attacks the cells that support smell-detecting neurons. Once infection clears, the sense of smell typically returns, though the exact timeline for that differs by patient. (Some users may experience a paywall.)

How Nobel Prize-winning research unraveled why the immune system doesn't always attack itself

The 2025 Nobel Prize was awarded to scientists who discovered how immune system soldiers are typically stopped from attacking healthy tissue. The work furthered autoimmune understanding and cancer therapies.

Two Lyme disease vaccines were in development in 2026

As of early 2026, there was no vaccine for Lyme disease available. One candidate vaccine, VLA15, was in later-stage clinical trials. Another designed to provide seasonal protection was licensed to a pharmaceutical company in 2025, and was planned for human clinical trials.

An overview on germ theory, the crucial framework developed by Louis Pasteur

Germ theory of disease is based on the concept that many diseases are caused by infections with microorganisms, typically only visualized under high magnification. Read this general overview to understand the basic framework which allowed for development of vaccines.

Long-haul COVID: What doctors want patients to know

Long COVID continues to be a medical mystery, but some parts of the puzzle are falling into place. Learn more from intensivist Devang Sanghavi, MD.

SAD 101 from the folks at NIMH—where the condition was first identified

Norman Rosenthal led the team at the National Institute of Mental Health that first identified and described seasonal affective disorder in 1984. This 101 from NIMH explores the basics of the condition, from who develops it to how it is treated.

Fungi make people sick when they invade and survive in otherwise healthy human tissue

We breathe in airborne spores frequently, but they often don't make us sick. This video details how certain concerning fungal changes can occur and discusses the role of mycologists—scientists who study fungi—in helping to improve human health.

Penicillin ended scarlet fever’s deadly threat to children

Between 1840 and 1883, scarlet fever was among the leading causes of childhood death in the United States, with case fatality rates ranging from 15% to 30%. Today, thanks to antibiotics like penicillin, the mortality rate is below 1%.

This decongestant doesn't work, so why is it still for sale?

Over-the-counter decongestants powered by phenylephrine won't help those with stuffy sinuses find relief, according to current evidence. This 10-minute video explores why these useless medications are still for sale in the US. The decongestant...

Lengthy incubation periods are why it’s tough to link foodborne illness to specific foods

People may not get sick from a foodborne pathogen for several days after consuming it, making it a challenge to link the illness and its cause. Factors influencing when a person starts feeling sick—even as the pathogen is multiplying in the gut—include individual variations in immune systems and gut microbiomes, what other foods are in the person’s body, and how much of the pathogen was consumed.

Efforts to create disease-sniffing capabilities for phones still can't match dogs

In this video, a scientist explains why dogs remain leaders in olfactory capabilities, outpacing technology. Scientists have attempted to create artificial "e-noses" for phones to detect early signs of disease, but so far they have not been successful.

The first major norovirus outbreak sickened half an elementary school

In 1968, 50% of an Ohio school got ill from this foodborne pathogen. The disease name is a nod to that original strain discovered in Norwalk, Ohio, when half the elementary school students became ill. Almost all kids reported nausea and vomiting. Everyone recovered.

Some of us can control our goose bumps

A small 2018 study examined the rare ability to control goose bumps. Researchers found some intriguing associations between having a particularly open and curious personality type and the ability to trigger this sensation—a link that they hope will be explored further in the future.

How a scientist discovered West Nile is spread by birds

Listen to Tracey McNamara, former chief pathologist at the Bronx Zoo, detailing her surprising late 1990s discovery that established West Nile virus is spread by birds. Financing animal disease surveillance studies, she says, saves human lives and surveillance gaps may fuel missed opportunities to identify dangerous diseases before they jump between species.

Jonas Salk developed the first successful polio vaccine—and tested it on himself

The American medical researcher developed the inactivated virus vaccine from 1952 to 1955 and proved that it could prevent disease. He tested the virus on himself and his family in 1954 and then carried out formal clinical trials on more than 1.3 million children.

Swimmer's ear is America's most common waterborne illness

Federal government analysis of the roughly 7 million waterborne illness cases that occur annually in the US found that swimmer's ear comprises some 4.7 million, or 65%, of the annual waterborne illnesses and 20% of hospitalizations. Norovirus infection comes in second place.

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

See the evolution of Ebola vaccine and treatment development.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Poison ivy can cause rashes year-round since all parts of the plant contain urushiol, the oil that triggers our allergic response.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Hurricanes, which rely on air consistently spinning in the same direction, cannot cross the equator because air curves in opposite directions north and south of it.

Despite being favored by 87% of Americans, Congress does not have term limits.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Some researchers have labeled nomophobia, the fear of being without your phone, as 'the phobia of the 21st century.'

20,000 letters to the advice columnist 'Dear Abby' provide insight into prevailing sex, religion, and LGBTQ fears, anxieties, and concerns from the 1950s onward.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Elk Cloner, the first computer virus to spread in public, was written as a practical joke by Richard Skrenta, a Pittsburgh high school student.

The United States has had a tumultuous relationship with Cuba since its 1959 revolution, highlighted by a nuclear crisis and a decades-long trade embargo.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Volcanoes 'die' when their supply of magma runs out, if they are shifted away from their underlying magma reservoir, or if they get clogged by collapsing or their magma cooling back into rock.

See how Budweiser's famous Clydesdales spend their days at Warm Springs Ranch, where roughly 70 to 80 of the beer brand's giant horses can be found at any given time.

Coral polyps reproduce via broadcast spawning, where entire reefs simultaneously release reproductive cells for about one hour, once a year.