This decongestant doesn't work, so why is it still for sale?

Stuffy nose congestion occurs because of swelling of the inferior turbinates

These structures in the nose above the nose hairs swell and shrink constantly and are affected by head position. They can fill with blood during illness, causing the feeling of congestion, but also when a person changes position, especially when lying down. Medications can be used to shrink them, providing temporary relief.

Why we don't have an answer for the common cold

Since a landmark study of the common cold in 1925, researchers have learned much more about the seasonal ailment. Despite continuous study, people still contract colds for similar periods of time at the same rate with the same symptoms, and there's no vaccine. This article explains how the many viral strains make it hard to control.

Home allergy tests don’t work well and experts urge caution

Doctors do not recommend at-home allergy test kits because their results may be inaccurate and confusing, and lead people to make lifestyle changes that are not warranted. Tests that require sending in a hair sample, for example, will not be helpful because hair does not have the relevant antibodies that blood testing would detect.

Scientists still don't know why DEET is such an effective bug repellent

This chemical, used to keep ticks, fleas, mosquitoes, and other nuisance bugs away, is used by an estimated one-third of the US population and has been available to consumers since 1957. Researchers theorize that multiple mechanisms may be at work to deter bugs, including perhaps masking or confusing bugs' olfactory receptors.

'Why'd I take speed for twenty years?': an exploration of stimulant ADHD medication

Many people with ADHD are prescribed stimulant medication to assist with symptoms ranging from time blindness to executive dysfunction. This hour-long podcast episode by Search Engine explores the host's experience with ADHD medication and the history of amphetamine and methylphenidate use in the US.

What is a sneeze? (And can it kill you?)

A sneeze is an important involuntary reflex to expel something that is irritating your nose. But can it kill you? No, say these silly video hosts. Although, the sneeze can expel air, saliva, and mucus at nearly 100 miles per hour in a five-foot radius. See them break it down with this quick, quirky video.

Why are drug dealers putting fentanyl in everything?

A few grains of fentanyl, a synthetic opioid far more potent than heroin or morphine, are enough to kill a typical adult human. It's made its way into other, less lethal street drugs, where it may be used to increase the highs experienced by unknowing users, increasing their likelihood of addiction and overdose.

US federal law dictates that all ads must not be deceptive

It also dictates that all ads must be “not misleading, and, when appropriate, backed by scientific evidence.” However, enforcing these laws can be difficult given the massive number of ads that run all over America each day. This explainer on the subject from the FTC provides more information.

How a black market for banned refrigerants still threatens ozone recovery and climate progress

Despite the Montreal Protocol's success, illegal trade in chlorofluorocarbons, hydrochlorofluorocarbons, and hydrofluorocarbons persists. Driven by high profits and weak enforcement, smugglers supply banned refrigerants, causing significant ozone depletion and greenhouse gas emissions equivalent to billions of tons of carbon dioxide.

Read this analysis indicating which traditional stevia medical uses have scientific evidence

This research paper investigates the various uses of Stevia rebaudiana leaves and their extracts and concludes that the substances do hold significant potential for improving cardiovascular health and inflammatory disorders in adults, among several other potential applications. Its authors suggest that further research should examine safe dosage questions and chronic disease management approaches.

If kids have ear tubes, over-the-counter ear drop solutions to clear buildup shouldn't be used

Mixes of acetic acid or alcohol to help speed water evaporation in the ears shouldn't be placed into children's ears if they have a hole in the eardrum or if they had ear tubes inserted—hollow cylinders made of plastic or metal that are inserted into the eardrum by a doctor to help drain fluid and improve airflow in the middle ear. Alcohol or acids can cause irritation to the middle ear and intense pain as they pass through the hole or tube.

America doesn't have enough estradiol patches for menopause and perimenopause demand

Fueled in part by the lifting of the FDA's black box warning about HRT risks, sales of estradiol patches in the US have shot upward. More than 142 million units of the patches were sold in 2025 versus 46.5 million in 2020. Suppliers are failing to keep up with demand—11 patch products were in short supply in early 2026. (Some users may experience a paywall.)

Anesthetics slow brain activity by promoting inhibitory neurotransmitters

Drugs like propofol and isoflurane increase activity at the GABA receptor, which opens chloride channels. These ions enter neurons and hyperpolarize them, making them less likely to fire. Dexmedetomidine instead blocks norepinephrine receptors in the brainstem to sedate patients.

FDA approved the first ever peanut allergy treatment in January 2020

This new medication, called Palforzia, is designed to stave off severe reactions from accidental peanut exposures with a daily dose that is increased over time under an allergist’s supervision. It’s not a treatment that should be administered during an allergic reaction, however. Epinephrine, usually administered via injection, remains the intervention for severe reactions.

Dollar stores often place staple items at the back of the store

This forces customers to encounter other, less-necessary items on their way there, leading to impulse buys. This video explains other ways that dollar stores make money while selling extremely cheap products, keeping dollar store profit margins relatively high.

Why dizziness is still a mystery

Dizzy spells can completely upend the lives of those suddenly struggling to find their footing. Despite this severe impact, the different flavors of dizziness and their sources continue to elude medical understanding. This article follows a health...

Rome's herbal panacea may not be as extinct as we thought

Silphion: cure-all, aphrodisiac, birth control, tasty seasoning. Nero allegedly ate the last of this miracle plant. This article details how a researcher may have found more. Seven centuries after the yellow-flowered plant was first documented growing in what's now Libya, it vanished. Historians proposed that the loss of Silphion may have been the first recorded extinction of any species.

Sugar alcohols, a type of carbohydrate used as a sweetener, may elevate risk of heart attacks and strokes

Sold as erythritol, sorbitol, xylitol, and mannitol, these products—ones that aren't actually sugars or alcohol—are found naturally in certain fruits and vegetables. They are synthetically produced to be used at much higher levels as the sugar alternatives for sugar-free candies, cookies, and chewing gums. Erythritol and xylitol have been linked with elevated heart attack and stroke risks.

Companies developing new weight loss drugs

In recent years, weight loss drugs made a tremendous amount of money for Novo Nordisk and Eli Lilly. Other companies are developing new drugs to break into the market. This piece is a concise overview of companies creating and testing new drugs, how far along they are, and what Novo Nordisk and Eli Lilly are doing to compete with these emerging rivals.

Conversation candy hearts were originally message-free medicinal lozenges

In 1847, a Boston pharmacist invented a machine that automated the production of his pharmacy's medicinal lozenges and then formed the New England Confectionery Company, which later became part of the company now known as NECCO. By the late 1800s, they were producing cookies with Valentine-themed messages and eventually brought the romantic messages to their smaller lozenges, which they later called Sweethearts.

Peptides like BPC-157 are marketed based largely on animal studies, not human research

BPC-157, which purportedly helps with tissue repair and muscle growth, can cause concerning side effects, including pain and swelling. TB-500, another experimental peptide, is marketed for wound healing, but it hasn't undergone any clinical human trials, and high levels of this peptide have been linked to tumor growth. (Some users may encounter a paywall.)

When a Paris department store hesitated to sell Estée Lauder's perfume, she 'accidentally' broke a bottle, causing the smell to spread throughout the store and shoppers to start asking to buy the scent.

How congestion pricing is trying to fix downtowns

Billions of gallons of gas are wasted each year as US drivers sit in traffic losing billions of hours of time. The congestion problems big downtowns face has led to innovative interventions to try to stop the traffic, including congestion pricing, a...

Why helium mixtures are used in respiratory medicine

Unlike the air near Earth's surface, which is primarily composed of oxygen and nitrogen, heliox is composed entirely of oxygen and helium. Because helium is lighter than nitrogen, the lungs do not have to work as hard to push air, easing the uptake of oxygen via a ventilator, mask, or nasal tube.

The human toll of the Philips' CPAP machine recall

A CPAP machine is an air pressure-generating motor that forces open the airways of those with sleep apnea, a condition that causes nighttime breathing interruptions. In 2021, Philips Respironics recalled millions of machines after finding the device's sound dampening foam was disintegrating, sending potentially dangerous particles and fumes into users' lungs. The company was warned thousands of times about the foam—something they hid from the public and government.

'Deinfluencing' explained

You’ve probably heard of influencers, but have you heard of “de-influencers?” Basically, the de-influencing trend started when creators began making videos about products you shouldn’t buy, rather than sponsored content promoting things you should purchase. Comedian Taylor Tomlinson recently cracked some jokes about the trend, and its companion “under consumption-core.”

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Despite being favored by 87% of Americans, Congress does not have term limits.

'Silent' fireworks have gained more interest in recent years as a quieter celebratory option.

Up to a million Girl Scouts sell about 200 million cookie boxes every spring, generating $800 million, largely because refusing a child is frowned upon

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

How the most famous Ebola book, The Hot Zone, which sold 3.5 million copies and was translated into 30 languages, got aspects of the disease so wrong.

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Netflix profits when you're not watching, and its movies are designed that way—read a detail-rich critical essay exposing lesser-known Netflix takes

Pure water does not conduct electricity because this flow of energy requires the movement of charged particles, and water is a neutral molecule.

Frank Lloyd Wright's houses are historically hard to sell because they're old, subject to local landmark commissions, and often unfashionable

A vending machine run with Anthropic's AI went out of business after it was convinced to give away items for free and sell a video game console.

A small portion of The Winstons' 'Amen, Brother,' an obscure '60s gospel record, is the basis for thousands of hip-hop tracks, making it one of the most sampled records ever that's informally known as 'the Amen break.'

Most of the observable universe's volume consists of voids and supervoids—enormous regions of space with little to no galaxies, stars, or light.

View the ten deadliest tornadoes in US history.

See how Budweiser's famous Clydesdales spend their days at Warm Springs Ranch, where roughly 70 to 80 of the beer brand's giant horses can be found at any given time.

Poison ivy can cause rashes year-round since all parts of the plant contain urushiol, the oil that triggers our allergic response.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

In preparation for this weekend's Eurovision finale, which is something like the World Cup of pop music, here's a young Céline Dion performing (for Switzerland?) at the 1988 competition.

Explore fun facts from the USPS, including unique post office buildings, a stamp that traveled past Pluto, and more.

The Nasdaq's 'Magnificent 7' companies are responsible for roughly 40% of the Nasdaq 100 index's gains, while the remaining 93 companies account for the other 60%.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.