Gut Microbiome

Overview

Our bodies are covered in rich ecosystems invisible to the eye and inhabited by trillions of microscopic organisms, which collectively make up the human microbiome. Of these, studies increasingly show that one of the most consequential microbiomes lies inside the digestive tract.

This 30-foot-long tube—which includes the large and small intestines—may have as many as 100 trillion microbes that help break down food, and perform other essential tasks, including producing hormones and neurotransmitters and training immune system cells. The exact makeup of the gut microbiome varies from gut to gut and changes across different stages of life, but is generally composed of yeast, protists, bacteria, viruses, and archaea. Finding ways to alter that composition and target specific microbes with future therapies is a key focus area as scientists learn about the microbiome's role in a wide range of mental and physical conditions, ranging from allergies to depression to autoimmune disorders.

Scientists hypothesize that the gut microbiome comes from bacterial colonization that slowly covers the body, inside and out, after birth. 

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