The gut microbiome, explained

A technical review of what researchers know about the gut microbiome

This overview from the National Institutes of Health provides a deeper (but still accessible) look at the different bacteria in the gut, how the microbiome develops through life, its purpose, and more.

How the microbiome affects your health

The gut microbiome is so influential to overall human health that some researchers consider it a separate organ. Its conditions, influenced by environmental and lifestyle factors such as medication and exercise, contribute to immunity, metabolism, inflammation, medical treatment efficacy, brain development and function, and the development of disorders and diseases, including asthma, depression, inflammatory bowel disease, and Alzheimer's.

Explaining the physical connection between the gut and brain

This video overview from Duke University helps visualize the gut-brain axis—a physical connection of nerves running from the brain to digestive tract that acts as a physical and chemical link.

What is the gut microbiome?

The gut microbiome is a microscopic ecosystem that runs off the work of microbes in the digestive tract. These workers make getting energy from food possible. What and how that energy manifests depends on what building blocks these microbes have to work with, meaning their composition and functions are strongly influenced by diet. Gut microbes have their own genes, which affect how a person's genes act.

Listen to how the gut microbiome influences your emotions

The gut-microbiome connection may involve the enteric nervous system, a collection of hundreds of millions of neurons throughout the gut that transmit signals up the vagus nerve to the brain.

What is a microbiome (and why are they important)?

Jump to: What is the microbiome? How microbiota benefit the body The role of probiotics Can diet affect one’s microbiota? Future areas of research What is the microbiome? Picture a bustling city on…

How to maintain a healthy gut

Approximately 40 trillion microbes reside in the human gut, forming a unique microbiome, containing hundreds of millions of neurons in what is often called a "mini-brain". A healthy gut is characterized by an effective mucus-lined barrier that prevents unwanted substances from entering the bloodstream. So how do you attain such an ideal gut? This guide outlines a healthy approach to protecting your gut.

What's next for gut microbiome science?

A Stanford microbiologist explores what we don't yet know about the gut microbiome—such as whether we can engineer the bacterial species within it—and the current scientific advances in the field.

Microplastics 101: What we know about the contaminants invading our bodies

Fifty-one trillion particles of microplastics float in our oceans. Yet there is very little science of how this affects our health. This quick 2-minute video explains the dangers of microplastics.

This is what happens inside your body when you're sick

This video details the biology of what happens inside the human body during illness.

A fascinating look at how our DNA is built and replicated

This easy-to-understand 13-minute video dives into the wondrous molecule deoxyribonucleic acid – also known as DNA – and explains how it replicates itself in our cells.

A doctor answers the internet's burning questions about the gut

Gastroenterologist Dr. Ugo Iroku answers the internet’s burning questions about digestion and bowel movements. Get the lowdown on what it means when your stuff is super dark, the impact of coffee on evacuating bowels, and much more.

GMOs sound scary, but you eat them every day

Why are GMOs bad? They aren’t. We’ve been eating them for decades with no ill effects, which makes sense, because a genetically modified organism is simply an organism, like every other organism, produces hundreds of thousands of proteins, but one or two of them are proteins that were chosen specifically by humans. Watch this 11-minute video for more.

A video introduction to demography

The Big Think’s video provides a thorough introduction to the field of demography. Demography provides the tools to address and understand many of the world’s problems. It uses quantitative data and mathematical models to analyze populations....

How epigenetics blurs the line between nature and nurture

An exploration of the study of how behaviors and environment affect the way genes work — and how that complicates the nature-versus-nurture debate.

Learn about the basic anatomy of mosquitoes

This short explainer video breaks down the mosquito's general body components, highlighting how mosquitoes breathe, fly, and more. It also touches on how experts can tell different mosquito species apart.

Fungi can cause disease, but they’re also our planet’s key decomposers

Fungi are their own taxonomic kingdom separate from flora and fauna, acting as the key decomposers and nutrient recyclers for our planet. Watch this video to understand the diverse types of fungi and the stages of the fungal life cycle. This video illustrates how fungi species may spread, eat nematode worms, damage nearby plants, and much more.

A scale of the universe, from atoms to cosmos

Can you really appreciate just how small protons are, or how massive the universe is? To attempt to grasp it, watch this short video which zooms out from a young woman in California to the very limits of the cosmos using established scales. Then, dive deep into the atoms of her white blood cells for a fully-rounded effect.

Imagining the farms of the future

About 10,000 years ago, humans began to farm. This agricultural revolution was a turning point in our history and enabled the existence of civilization. Today, nearly 40 percent of our planet is farmland. Spread all over the world, these lands are the pieces to a global puzzle we’re all facing: in the future, how can we feed every member of a growing population a healthy diet? Brent Loken investigates in this seven-minute video.

The interoperable metaverse and what that means

This explainer video explores the challenges of achieving the interoperability needed to unify economies, avatars and systems across virtual worlds in the metaverse.

The world's different calendars, explained

The calendar we use to mark the days, months, and year can feel set in stone, but the history of calendars shows these organization systems can and do change. Parse the fascinating, complex details of the Gregorian, Julian, Chinese, Hebrew, and many more calendars in this comprehensive, well-executed explainer video.

Explore the history of antibiotics with 'This Podcast Will Kill You'

The show blends medical history with storytelling and science. In Episode 50, the hosts trace the dramatic origins of antibiotics—from Fleming’s moldy petri dish to Florey’s wartime labs—and explore their lasting impact on health.

A deeper walk through of the four stages of sleep

In this TED video, sleep expert Matthew Walker carefully breaks down the sleep stages along with a description of why each is important. He finishes the discussion by examining the consequences of altered or decreased sleep, and why seemingly small alterations in our sleep patterns can have outsized effects.

Can we speed up our metabolisms?

Listen to this 31-minute podcast to better understand what science knows and doesn't know about metabolism, as well as the only thing that seems capable of changing it. Scientists understand that the difference between a so-called “fast” and “slow” metabolism does not affect one’s ability to lose weight.

The British Empire, explained

This three-minute 1440 explainer traces the rise of the British Empire, which at its height ruled nearly one in four people—about 500 million—and spanned so many regions that admirers called it “the empire on which the sun never sets.”

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Explore the history, structure, and species of Australia's Great Barrier Reef with this interactive journey narrated by Sir David Attenborough.

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

After NASA's Voyager 1 captured Earth as a single pixel as it left the solar system in 1990, astronomer Carl Sagan used the image to reflect on humanity's fragility and the responsibility to protect 'the only world we've ever known.'

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Tattoos remain visible on your skin thanks to immune cells called macrophages

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Watch this video that uses Lego bricks to explain how venture capital works.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Hear 50 years of iconic hip-hop samples, the genre's foundational looped tracks

Netflix profits when you're not watching, and its movies are designed that way—read a detail-rich critical essay exposing lesser-known Netflix takes

According to the physics of black holes, our 4D reality may be a hologram—a projection of information coded on a 2D surface on the edge of the universe.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

In 1963, a basement renovation in Turkey revealed a passageway to a hidden, multilevel underground city that once housed as many as 20,000 people

US consumers collectively owe more than $1T to credit card companies—almost as much as they owe in auto loans.