Red blood, skin, hair, and nail cells destroy their DNA upon maturing

Explore the abundance of different types of cells in the human body

Lacking a nucleus and other organelles to maximize space for oxygen-carrying hemoglobin and enhance maneuverability through narrow capillaries, there are about four times as many red blood cells and platelets as all other cell types in the body combined. However, about half of the body's cell biomass consists of skeletal myocytes, or muscle fibers.

DNA damage and chemical stress causes cellular aging

While outward signs of aging, like gray hair and wrinkles, are easy to spot, aging changes at the cellular level are less obvious. The decline within cells stems from numerous sources, including DNA damage, oxidative stress, and accumulated waste.

New blood cells are created by hematopoietic stem cells

Blood is made up of several cells with various functions and short lifespans, so the body must have a constant supply of replacements. These replacements are created by hematopoietic stem cells, rare cells that live in bone marrow and can regenerate themselves and blood cells.

Cells can last in the human body from days to a person's entire life

Despite claims that a person's body replaces itself every seven to 10 years, the rate at which cells die and are replaced varies by cell type. Gastrointestinal cells that line the digestive tract and stomach last only a few days, while some heart muscle cells and most neurons are around from birth until death.

Watch DNA replicate itself before cell division

In the average adult human, between 50 billion and 70 billion cells die daily, requiring them to replicate their genetic instructions before dividing into new cells. This process relies on various proteins to unwind, read, build, and proofread new strands, with error rates of fewer than one per 1 billion nucleotides.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

Cells are categorized by the presence of contained genetic material and other organelles

While prokaryotes contain one or more cells with free-floating genetic material in a region called the nucleoid, eukaryotes possess a nucleus specialized for DNA storage. Plant cells possess cell walls—a reinforced structure surrounding their membrane—made of cellulose, while fungal cell walls contain chitin. Animal cells have lysosomes housing enzymes that break down biomolecules. (Some readers may experience a paywall.)

Stem cells can reboot the ability of cells to repair themselves

Stem cells—special cells that can self-renew and evolve into new cell types—may provide a path to address aging. Instead of repairing aging cells, stem cells can replace a cell's "repair kit," effectively rebooting the internal processes of tissues to a more youthful state.

DNA may serve as a flame retardant by self-extinguishing some burning materials

When DNA burns, phosphate groups release phosphoric acid, and nitrogenous bases release ammonia. These molecules, along with the sugar in DNA's backbone, shift the combustion reaction toward the formation of intumescent char. This puffy, carbon-rich layer protects open flames from burning the material beneath.

Necrosis is the unplanned death of cells and the tissue they comprise

If cells die prematurely due to a lack of blood flow, injury, or disease, they and their organelles can swell, leading to rupture of the surrounding cell membrane. This releases the cell's contents into the surrounding tissue, causing inflammation and damage to neighboring cells.

Mitochondria—only inherited from mothers in most animals—have their own DNA

Mitochondrial DNA, or mtDNA, typically takes the shape of a circle and contains genes that code for proteins essential to the production of energy-containing molecules called ATP. When mitochondria fuse, the mixing of healthy and damaged mtDNA helps alleviate the effects of mutations that may have occurred during mitochondrial division or environmental interactions.

Symptoms of DNA loss may mimic those seen in mushroom poisoning or chemotherapy

Although no organism has ever lost all its DNA, the destroying angel mushroom contains amatoxin, which disrupts DNA transcription and is known to cause death via liver and kidney failure in three days. Doxorubicin, which tangles DNA to disrupt cellular replication, compromises a person's immune system.

Humanity's reduced body hair slows down wound healing

Cuts to human skin take twice as long to heal compared to chimps and other mammals. Scientists argue this is due to the reduced number of hair follicles on human bodies. Hair follicles contain stem cells which help repair skin cells faster, so as humanity shed its hair over time, so to speak, it also slowed its wound healing.

Changing a single letter in DNA can permanently alter an organism

Genetic mutations occur when cells replicate, which requires a copy of DNA to be created, and involve substituting, deleting, or inserting letters in a cell's genetic code. Mutations can be caused by normal cellular processes, chemical exposure (e.g., carcinogens), or radiation and may result in genetic disorders or genetic variations that drive evolution.

How metabolism, when cells convert molecules into energy, works

Metabolism is when a cell’s internal network of chemical reactions breaks down food molecules and transforms them into pieces of the cell itself. Sometimes, cells build replacements for worn-out parts. Other times, they build energy molecules that power the cell’s activities.

See what loud noises do to inner ear hair cells

This animation illustrates how louder music can affect inner ear hair cells. Damage to these cells is generally considered permanent. Hearing protection like ear plugs can reduce the level of sound entering into the ear and help protect those cells.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

The body can remove tattoos after they are broken down by laser

Tattoos place blobs of ink below the surface layers of the skin in packets too large for white blood cells to clear out. By breaking the ink into smaller pieces, they can be processed by the immune system, which is responsible for removing foreign matter.

Oxygen and nutrients are circulated in tardigrade bodies through physical movement

Rather than having a circulatory system, oxygen is directly absorbed through their skin and spreads through a fluid called hemolymph as tardigrades crawl. When molting to grow, they shed their outer skin and stylets—sharp mouth parts used to pierce prey—which are regrown in their salivary glands.

Tattoos remain visible on your skin thanks to immune cells called macrophages

Plants use physical and chemical defenses to protect themselves

Tree bark is difficult to chew and resistant to pathogens, while the waxy cuticle on the surface of leaves deters insects and microbes. Some plants possess thorns, spines, and prickles to discourage predators. Plant cells can also produce antimicrobial toxins or release compounds to alert parasitic wasps to lay eggs in attacking insects.

Sleep deprivation leads to buildup of danger molecules in the gut

Fruit flies genetically engineered to be awake for as long as they live tend to live half as long as their well-rested brethren. Analysis shows these modified flies suffer from a buildup of DNA-destroying reactive oxygen species in their guts. When enabled to sleep, the flies live as long as their counterparts.

A Death Valley shrub optimizes its cells' organelles to photosynthesize in extreme heat

Examining the cellular structure of the plant under heat, scientists observed the formation of novel, cup-shaped chloroplasts and mitochondrial relocation, which shifted the plant's optimal photosynthesis temperature to 45 degrees Celsius (113 degrees Fahrenheit) as it tripled in mass over 10 days. Engineering these mechanisms in crops may help optimize them for hotter environments.

During the fall, chlorophyll breakdown in leaves produces color changes

With shorter days and less sunlight, the concentration of the green pigment diminishes, revealing yellow and orange pigments. Red leaves result from trapped sugars, producing new pigments called anthocyanins, which weren't present in leaves during the growing season.

Collagen supplements have become a multibillion-dollar industry

Beginning in our 20s, the amount of this protein in our skin, muscles, and connective tissue declines. But independent, high-quality studies—like those that are double-blind—have not yet shown a significant association between their use and evidence of it improving skin elasticity, reducing wrinkles, or combating hair loss. Some collagen supplements do seem to help with joint pain and knee function, but NPR cautions that studies on that purpose are industry-funded.

Why Earth would become a more deadly environment without the ozone layer

The ozone layer blocks almost all of the sun's harmful, including dangerous UVC rays that can damage cells by breaking chemical bonds. Without it, rates of skin cancer, crop failures, oceanic die-offs, and widespread ecosystem collapse would increase significantly, making Earth largely uninhabitable.

Chromium contaminants in a ruby crystal gave the world's first laser its red color

The red light originates from a long-lasting excited electron state in the element's atomic structure. The brittle gray metal has historically been used in pigment production, the manufacturing of rust-resistant stainless steel, and the creation of durable coatings with long-lasting shine for metals, wood, and leather.

The economics of horseshoe crab blood

Horseshoe crabs are older than dinosaurs and have survived five mass extinctions that wiped most life from the planet. But it's only now that their future as a species is in danger. This blood, worth about $60,000 per gallon, is hyper-sensitized to certain bacteria that are fatal to humans. This 17-minute podcast dives into humanity's pursuit of horseshoe crab blood, a "somewhat magical" mixture heavily relied on by the pharmaceutical industry.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Coral reefs get their colors from zooxanthellae—microorganisms that line corals' digestive tracts and provide them with sugars in exchange for a home within this protective tissue.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Poison ivy will likely become both larger and more resilient due to climate change.

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

The original copy of the Declaration of Independence is not a pristine document, and even features a smudged anonymous handprint in the bottom left corner.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

Power lines are dotted with large, brightly colored balls to improve the visibility of these thin wires to helicopters and small planes and help prevent potential crashes.

Some coin denominations have ridges etched on their sides, partly to prevent counterfeiting, in a practice called 'reeding.'

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Pure water does not conduct electricity because this flow of energy requires the movement of charged particles, and water is a neutral molecule.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Some researchers have labeled nomophobia, the fear of being without your phone, as 'the phobia of the 21st century.'

Prince's sexually explicit 1984 track 'Darling Nikki' attracted the ire of the Parents Music Resource Center, an advocacy group that inspired the Parental Advisory sticker, even though the song ends with a Christian message.