Heatstroke treatment guidelines were built almost exclusively on research in men

Reduced inflammation from cold plunges lacks scientific support

The cold water triggers immediate cold shock, increasing heart rate and blood pressure, and prolonged exposure can lead to cold-water incapacitation and hypothermia. Plungers are encouraged to enter the water slowly and manage their breathing to reduce the risk of shock. Warm baths post-plunge are discouraged, and exercise is generally better for recovery.

Heatstroke occurs when the body reaches 104°F or higher and can't cool itself

Untreated, this medical emergency can result in permanent disability or death. Someone suffering from heatstroke—defined as a core temperature of 104 degrees Fahrenheit but sometimes as high as 106 degrees Fahrenheit—may appear confused and require immediate cooling, ideally with an ice bath.

Health workers may cool body temperatures with convection cooling

That's spraying a patient with water and putting fans over them. Cooling the body by removing clothing and placing cold water and ice packs—and not blocking evaporation—are essential cooling steps.

Heatstroke deaths may be massively undercounted—perhaps by a factor of 10

One often-cited average estimate of annual American heat deaths—roughly 1,200 per year—is based on death certificate data, but it may be a significant undercount because heat kills through cardiovascular, kidney, and respiratory causes that are more likely to be cited on those documents. (Separate analysis that looked at data from 1999 to 2023 found that the highest number, in 2023, was 2325.)

Korey Stringer, of the Minnesota Vikings, died of heat-related illness in 2001

In response, the NFL overhauled its heat approach and no other player has since died from heat-related illness. Even at the high school level, research suggests safety measures should include: mandating water breaks, keeping a cool tub available, and having athletes acclimate to high-temperature playing conditions for a week or longer before donning the full set of protective equipment.

Supplements ahead of exertional heatstroke helped protect mice against brain damage

In the lab, mice dosed with probiotics prior to inducing exertional heatstroke, had better cognitive outcomes. This evidence underscores the links between the gut microbiome and the brain, at least in rodents.

Heat-related complications are of greater concern for distance runners than cardiac threats

Analysis of more than 130,000 runners in Tel Aviv events during a seven-year period indicated that the runners were 10 times more likely to experience heatstroke than serious cardiac problems. Scientists suggest that runners should take 10 to 14 days to acclimate to a hot climate before tackling a serious run.

Certain medications that affect blood flow or mood boost the risk of heatstroke

Drugs that narrow blood vessels, beta blockers that regulate blood pressure, diuretics, antidepressants, and antipsychotics can all affect the body's ability to regulate its internal body temperature, and so individuals taking these medications need to take special care in extreme heat and when exercising in hot conditions.

How to survive hypothermia

Hypothermia is a deadly risk for those living in cold areas, causing around 1,500 deaths a year in the United States. Stay safe with tips from this article, which cites research papers to help prevent and treat the condition. Take note of the best fabric to wear when cold weather hits—not cotton but wool.

Extreme heat puts people at risk of developing kidney stones

It's essential to remain hydrated in summer weather to keep your body healthy, but one reason is to help dilute minerals that naturally build up if they aren't excreted in our water-fueled urine. Doctors recommend people generally drink 64 ounces of water a day and also eat foods with salt to help ward off dehydration.

Within months of a landmark 2002 study that indicated HRT harms, sales dropped by about half

In the early 2000s, Women's Health Initiative studies indicated HRT increased risk of breast cancer, heart disease, and stroke in some women—so many physicians stopped prescribing it to help with menopause symptoms. But further research has concluded that much of the elevated risk was overblown and that it was also disproportionately seen in women in their 70s who had been taking an older HRT formulation.

Headache disorders have historically been neglected and under-researched

Confusion between the variety of headaches—from mild discomfort to debilitating pain—and gender bias—migraines primarily affect women—have led to widespread misunderstandings of the medical issue. Medical students in the US may get as little as 30 minutes of instruction on the three major types: migraines, cluster headaches, and tension-type headaches.

Gatorade was first designed for college football players in Florida heat

To help replenish crucial chemicals football players were losing fast to their profuse sweat in southern heat, researchers at the University of Florida developed a drink blended with salts and sugars that were easy to absorb. The drink, Gatorade, took its name from the school's mascot.

Cold-blooded reptiles seek heat, and that behavior may help combat fungal infections

This Radiolab podcast episode takes on the idea that though our human bodies are too warm for the majority of fungal species to effectively replicate inside our bodies, that's not the case for reptiles. Yet when those species warm their bodies by basking in the sun on rocks, they can soak up heat and may also help keep fungal infections in check.

Women typically have more robust immune responses than men

This difference helps women better combat infectious diseases, but this more turbo-charged response may also make women more vulnerable to autoimmune diseases by potentially priming their immune systems to overreact to their own cells and tissues and label them as invaders that must be destroyed. Roughly 80% of American women have autoimmune conditions.

Humans have used geothermal resources for thousands of years

In North America, Indigenous peoples viewed hot springs as sacred places and used them for medicinal purposes, cooking, and surviving cold weather. The ancient Greeks and Romans also viewed them as sacred, partaking in hot mineral baths to relieve ailments and using them for space heating.

Civilians on short-term spaceflights can experience long-term astronaut health impacts

A collection of 44 studies—primarily based on data from a 2021 tourist trip to low Earth orbit—identified immune system disruption and some kidney damage in tourists, with women appearing to recover from space travel faster than men. Return trips from Mars may require human travelers to be on dialysis.

Brain death is a medical diagnosis without any wiggle room

Seeking to resolve long-standing variations between hospitals and state procedures, in 2023 several expert groups published comprehensive step-by-step guidance for clinicians to follow when determining brain death in kids and adults. Among other guidelines, it stated that doctors don't need to get family consent to do the tests needed to make this determination.

A look at the concentrations of water in the human body and various organs

When we're born, about three-quarters of our bodies are composed of water, dropping to an average of 55-60% for the average adult. The lungs are over 80% water, the kidneys and spleen about 80%, and the heart and brain are approximately three-quarters composed of water—about the same moisture as a banana.

Validation of the greenhouse effect may have been misattributed

Although Irish physicist John Tyndall showed in 1859 that water vapor and carbon dioxide could absorb and radiate infrared radiation, experiments by American scientist Eunice Foote three years earlier identified the same phenomenon for light in general. Historically overshadowed, her work was rediscovered by female historians over a century later.

How race science influences breast cancer research

Despite researchers' and physicians' pushback, race is still used in studies and clinics to categorize human differences in health conditions and treatment responses. This article explores how race has influenced breast cancer research. Considering race as a factor in cancer research, diagnosis, and treatment can lead to racial inequalities. Sociocultural factors, including food access and air pollution, greatly influence health outcomes.

Men and women didn't evolve to perform segregated hunter-gatherer duties

The often-cited theory that men evolved to hunt and women evolved to gather is wrong. This article explores the origins of the "Man the Hunter" theory and the mounting evidence that undermines it. Exercise science indicates that those assigned...

Six of history's most unethical human experiments, from deliberate flu exposure to withholding syphilis treatment

Some of the progress made in mental health treatment, vaccines, blood transfusions, and more came about before the advent of consent and ethics committees, resulting in serious physical and psychological harm that participants in studies were not even anticipating.

Humans aren't the only mammals who go through menopause, but it's rare in the animal world

While scientists are unsure how many mammals actually experience menopause, they do know for sure that humans aren't the only ones. Orcas and some toothed whales (like belugas and narwhals) go through menopause. And a recent study found chimpanzees also experience the condition, though it's late in life.

Staying on standard time permanently would slightly reduce obesity and stroke risk

A 2025 study that examined time changes found that permanently changing to standard time would slightly reduce obesity and stroke risk more than switching to permanent daylight saving time.

The boiling temperature of water decreases with increasing elevation because the molecules need less energy to overcome the lower atmospheric pressure associated with thinner air.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

Scientists testing how climate change affects plants found, in a years-long simulation study, that poison ivy grew 70% faster with the resulting extra carbon dioxide.

The history of many kitchen appliances involves unexpected discoveries and applications, including wartime radar turned hamster defroster and replacing an 'ice king' with heat-stealing boxes.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Watch the cumbersome, but necessary, precautions healthcare workers must take to care for and protect themselves while caring for Ebola patients.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

Animal phobias are likely the most common type of phobias, followed by an extreme fear of heights.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

11 people died from firework injuries in the US in 2024.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

When you complete a CAPTCHA on a website to prove you are human, you may be unknowingly training algorithms for self-driving cars, whose systems require training data to help identify crosswalks, bicycles, and other outdoor objects.

While El Niño moves warm Pacific Ocean waters east along the equator, La Niña moves them west, shifting where rainfall will become more common for months.

See how Budweiser's famous Clydesdales spend their days at Warm Springs Ranch, where roughly 70 to 80 of the beer brand's giant horses can be found at any given time.

Stanford built a Google Maps for the Roman Empire, revealing how much it cost to travel in the ancient world

Georgia O'Keeffe's flower paintings are often assumed to be sexual, though the artist claimed she was simply interested in highlighting the beauty of flowers that most people neglect

Brandi Chastain, the star of the 1999 US victory over China in the 1999 Women's World Cup, was a last-second choice to take the penalty kick that sealed the victory.

Watch how deep-sea mining equipment collects and processes polymetallic nodules—metal-rich, potato-shaped rocks—from the ocean floor and creates environmentally damaging plumes of sediments.

The US Constitution is widely regarded as the longest-standing written national constitution still in force—see how it has influenced rights worldwide.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

The Brothers Grimm were lawyers before they were storytellers, but became interested in fairy tales as they began investigating how rules and customs had been passed down through cultures.