Stevia has been used to treat burns and indigestion

Read this analysis indicating which traditional stevia medical uses have scientific evidence

This research paper investigates the various uses of Stevia rebaudiana leaves and their extracts and concludes that the substances do hold significant potential for improving cardiovascular health and inflammatory disorders in adults, among several other potential applications. Its authors suggest that further research should examine safe dosage questions and chronic disease management approaches.

Stevia is a plant-derived sweetener but the plant isn't approved for eating

Steviol glycosides, the sweet-tasting stuff in the plant leaves, are purified and highly processed before they end up in the food or drinks sold in stores. The US Food and Drug Administration does not allow the use of stevia leaf or crude stevia extracts in food, and the agency also bars them from being imported into the US for use as sweeteners.

The ancient Romans invented the first known artificial sweetener—it involved lead

The product was known as "sugar of lead." It was made by boiling wine in lead pots, concentrating the grapes' natural sugars and adding sweetness from the lead that leached into the grapes. The substance was used until roughly the 1880s for medicinal purposes and also to sweeten wine. (Some users may encounter a paywall.)

Saccharin was widely used in WWI when sugar was rationed

The substance was discovered by chemists in 1878, but its use became more common during World War I and also afterward as a result of sugar rationing. It had become a typical household item in the US and Europe by 1917. During World War II, the artificial sweetener again saw significant popularity.

Artificial sweeteners may disrupt gut health

Some research suggests that certain sweeteners can throw off the balance of beneficial bacteria in the gut and shift the composition of the microbiome. Such changes, depending on an individual's specific gut flora and levels of sweetener consumption, could potentially affect metabolism and glucose tolerance or lead to bloating and diarrhea.

See how sugar stacks up against the sweetness of sugar alternatives

This US Food and Drug Administration graphic compares different approved sugar alternatives to give the public a sense of just how intensely sweet these sweeteners are compared to table sugar. Aspartame (NutraSweet and Equal), for example, is 200 times sweeter, Sucralose (Splenda) is 600 times sweeter, and Saccharin (Sweet'N Low) is between 200 and 700 times sweeter.

What is salvia divinorum?

After centuries of use by Mexican spiritual healers, Salvia divinorum is surging in popularity in the U.S. — and the government has taken notice.

Rome's herbal panacea may not be as extinct as we thought

Silphion: cure-all, aphrodisiac, birth control, tasty seasoning. Nero allegedly ate the last of this miracle plant. This article details how a researcher may have found more. Seven centuries after the yellow-flowered plant was first documented growing in what's now Libya, it vanished. Historians proposed that the loss of Silphion may have been the first recorded extinction of any species.

Sugar skulls are more than a sweet snack

The colorful candy combines Indigenous traditions with European confectionery techniques. Its symbolization reminds celebrants that death can be “sweet.”

Aspirin was the first synthesized anti-inflammatory drug

Once used by the ancient Sumarians—extracted from willow bark—but now synthesized in the lab, the active ingredient of this popular medication has been used to treat headaches and pain for thousands of years.

Over time, people develop a resistance to spicy foods

TRPV1 is a receptor in the body that detects potentially harmful things and responds in a variety of ways, including sweating, tearing up or a runny nose. Over time, more exposure to spicy foods can build up a resistance that minimizes these reactions.

Oral rehydration solution was developed in the 1960s in response to cholera deaths

Drinking this life-saving mix, which consists of clean water, salts, and sugar, helps the human body rehydrate after extreme bouts of diarrhea, vomiting, or both. It's now used for a variety of diarrheal diseases.

A delicious flavor used to be made from a beaver’s butt

Love vanilla-flavored foods? Well, it was once made from castoreum - a yellowish exudate from the castor sacs of mature beavers. And the FDA regards castoreum as “natural flavoring."

Humans have used geothermal resources for thousands of years

In North America, Indigenous peoples viewed hot springs as sacred places and used them for medicinal purposes, cooking, and surviving cold weather. The ancient Greeks and Romans also viewed them as sacred, partaking in hot mineral baths to relieve ailments and using them for space heating.

Tirzepatide: A GLP-1 drug that also acts on separate receptors to promote weight loss

Tirzepatide, like semaglutide, is a GLP-1 drug used in diabetes treatment and for weight loss. Unlike semaglutide, it also acts on glucose-dependent insulinotropic polypeptide receptors, proving a second route to reducing appetite as a means to treat diabetes and promote weight loss.

The long history of an ancient Andean beer made from corn

And often chewed before brewed. From dank chicherias in small towns to gourmet big-city restaurants catering to tourists, the traditional fermented-corn beverage chicha is still being drunk throughout the Andes. Read more here.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

This scientist treated her own cancer

Virologist Beata Halassy treated her own breast cancer by injecting the tumor with lab-grown viruses. Though this self-treatment worked, it has not been approved for widespread use. Read to learn more about her fascinating experience, and how it has led to conversations about safety and ethics.

Gastroliths, or ‘stomach stones,’ help animals digest plants in their stomachs

Most often used by birds and reptiles, gastroliths help break down the cellulose of plant cells, which can resist decomposition from stomach acid alone. Over time, gastroliths become smooth and are regurgitated before being replaced by larger stones.

Cane toads are an example of an intentional species introduction turned invasive

In 1935, Australian scientists imported several hundred cane toads to hunt and eat beetles that were damaging sugar cane fields. However, the toads could not reach the bugs at the top of the plant or the grubs in the soil. Instead, they negatively affected native species populations as their numbers grew to over 2 billion.

Fiji's 'quiet' diabetes crisis

Across the Pacific archipelago of Fiji, diabetes often avoids diagnosis until amputation or death is imminent. Fiji's government has said nearly 30% of its population has diabetes, and, in 2019, related amputations accounted for 40% of the country's hospital operations. This "sugar disease" may have such a stronghold on the archipelago, which has a physically active culture that prizes locally sourced foods, due to cost, with processed foods being much cheaper than alternatives.

Colombia exported 35,000 tons of greens for Valentine's Day bouquets in 2025

The country is home to the green foliage that pads out Valentine's Day bouquets. Over 70% of the country's Valentine's Day exports (an operation that includes 500 flights) went to the United States. Environmental activists warn that the large-scale cultivation is harming a fragile ecosystem.

More than 200,000 people are diagnosed with leprosy annually

The disease still occurs in more than 120 countries. Brazil, India, and Indonesia continue to report more than 10,000 new cases annually.

Kansas City barbecue makes use of 'burnt ends'

The Midwest city has its own delicious tradition, serving the double-smoked chunks of fatty brisket slathered in the region’s signature thick, sweet-and-spicy sauce.

DNA may serve as a flame retardant by self-extinguishing some burning materials

When DNA burns, phosphate groups release phosphoric acid, and nitrogenous bases release ammonia. These molecules, along with the sugar in DNA's backbone, shift the combustion reaction toward the formation of intumescent char. This puffy, carbon-rich layer protects open flames from burning the material beneath.

Poison ivy's rash-causing compound is found in the plant's roots, stem, and leaves—so coming into contact with any part of the plant can lead to rashes for the 85% of people who are allergic to it.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Ebola species have historically been named after where they were discovered, stigmatizing residents who live there, including Bundibugyo, in Uganda.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

In 2018, 26-year-old missionary John Allen Chau was killed by tribesmen after attempting to reach and evangelize on India's isolated North Sentinel Island

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

When a Paris department store hesitated to sell Estée Lauder's perfume, she 'accidentally' broke a bottle, causing the smell to spread throughout the store and shoppers to start asking to buy the scent.

Before writing 'Walden,' transcendentalist Henry David Thoreau nearly burned down his hometown with a campfire that grew out of control.

See how Budweiser's famous Clydesdales spend their days at Warm Springs Ranch, where roughly 70 to 80 of the beer brand's giant horses can be found at any given time.

Coral reefs get their colors from zooxanthellae—microorganisms that line corals' digestive tracts and provide them with sugars in exchange for a home within this protective tissue.

In 1984, Operation Smash Hit intentionally crashed a 239-ton train into a nuclear waste canister at 100 miles per hour to prove the canister's safety, which remained completely intact and lost just 0.29 of its 100 pounds of pressure.

Some coin denominations have ridges etched on their sides, partly to prevent counterfeiting, in a practice called 'reeding.'

The boiling temperature of water decreases with increasing elevation because the molecules need less energy to overcome the lower atmospheric pressure associated with thinner air.

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After the Boston Tea Party, colonists switched to coffee, which became the main morning drink for revolutionaries.

Long before Major League Baseball began allowing instant replay for balls and strikes, an umpire reluctantly used the technology to determine whether a hit was a home run, a move that inadvertently ushered in a new era for the sport.

US intelligence allegedly pursued more than 600 schemes to assassinate Cuban revolutionary Fidel Castro.

Massive 3D printers have been used to build homes by stacking layers of 'concrete toothpaste,' a fire-resistant material that effectively insulates against outside noise.

Georgia O'Keeffe's flower paintings are often assumed to be sexual, though the artist claimed she was simply interested in highlighting the beauty of flowers that most people neglect

Stanford built a Google Maps for the Roman Empire, revealing how much it cost to travel in the ancient world