Children under 5 account for 76% of all malaria deaths in Africa

The most severe form of malaria is caused by the Plasmodium falciparum parasite

Multiple species of a single-celled organism called a protozoa cause malaria infection when transmitted by a mosquito bite. But Plasmodium falciparum is the most widespread in Africa, and the most deadly.

Hear what it's like to have malaria

In Kenya, as one malaria-sufferer explains, the disease is common enough that anytime a child has a fever or any sort of sickness families and the community will wonder if it's malaria. Sleeping under a mosquito net is recommended. Unfortunately, a gin and tonic will not keep malaria at bay.

There may be 500,000 additional malaria deaths by 2050

Research published in the journal Nature in January 2026 estimates that by 2050, climate change may trigger more than half a million additional malaria deaths and over 100 million additional malaria cases. The work is based on climate change projections and available disease information and did not incorporate new vaccine uptake.

See this graphic of the complex malaria transmission lifecycle

Female Anopheles mosquitoes contract malaria by feeding on the blood of a human already infected with the disease-causing parasite. The parasite then develops in the mosquito's gut for one to two weeks before it migrates to the mosquito's salivary glands. Next, when the mosquito bites another person the parasite is delivered into the bloodstream of another human. This graphic further details what happens inside the human body during infection.

There are two recommended malaria vaccines

Two vaccines are currently recommended by world health experts for children living in areas where malaria transmission is common. The first, RTS,S/ASO1, formally became recommended for use by the World Health Organization in October 2021, and the second was approved by the WHO two years later. Both have faced logistical, financial, and uptake challenges.

Mosquitoes top the ranking of the world's deadliest animals

Mosquitos kill about 760,000 people every year. The vast majority of those deaths are caused by malaria, which is transmitted and spread by the Anopheles mosquito. The second-place deadliest animal title goes to snakes, with an estimated human death toll of around 100,000 annually.

Pregnancy makes someone more attractive to the mosquito species that transmits malaria

Research suggests that hormonal levels can affect mosquito attraction. Pregnancy, in particular, is associated with significantly increased interest from Anopheles mosquitoes, which boosts pregnant women's malaria risk.

Malaria comes from the Italian term 'mal'aria,' meaning 'bad air'

The term refers to marshy areas associated with the disease. An estimated 94% of malaria cases—215 million—occur in Africa.

Under-5 child mortality has been cut in half since 2000, UNICEF reports

The United Nations Children's Fund works globally to protect children's rights and well-being. Its 2024 report on child mortality reveals that under-5 deaths have halved since 2000. The report includes interactive data visualizations that can be sorted by year or topic.

Yes, many animals get malaria—not just humans

Birds, rodents, monkeys, lizards, bats, apes, and livestock are among the species that can become infected with malaria. Infected animals' symptoms often resemble those of humans, including fever, lethargy, loss of appetite and difficulty breathing. Birds will also have ruffled feathers and drooped heads.

Neglected tropical diseases affect more people than the population of Europe

This group of conditions, which includes hookworm, sickens roughly one in seven people on the planet—a tally which dwarfs Europe's population of roughly 450 million. International cooperation and donations are helping to control some of these illnesses, which can be caused by parasites, viruses, and bacteria. They're all treatable or preventable, but primarily occur among poor, isolated communities that may not receive adequate care.

Untreated malaria can lead to blocked blood vessels in the brain, coma, and organ failure

Malaria is treatable with medications, but sometimes even after treatment, infection can come back because the disease-causing parasite wasn't completely eliminated. Patients may also have symptoms that emerge years after the initial infection and treatment.

10 locally acquired malaria cases were reported in the US in 2023—a surprise

The cases, reported in Florida, Texas, Maryland, and Arkansas, broke a 20-year streak since there had been no reported locally acquired mosquito-transmitted malaria in the country since 2003, when there was a case in Florida.

Secondary complications from measles in children range across the whole body

The most serious effects of a measles infection, particularly in young children, come from its attack on the immune system. This leaves the whole body vulnerable to follow-on diseases, with some of the most serious including respiratory conditions, encephalitis, and more.

Three Ebola species are responsible for most large outbreaks of the disease, yet the only approved Ebola vaccine is known to work against just one of them.

There have been close to 40 Ebola outbreaks since 1976

Ebola is a rare but deadly virus that causes severe illness, organ damage, and sometimes internal bleeding. It spreads through contact with infected bodily fluids and is most common in parts of sub-Saharan Africa. This explainer covers its symptoms, transmission, and treatment options.

Most cases of West Nile virus are asymptomatic in people

About 1 in 5 infected people develop symptoms from West Nile, including symptoms such as fatigue, head and body aches, and vomiting. But around 1% of patients develop severe complications such as encephalitis or meningitis, which can be life-threatening. Those who are most likely to become severely ill are people over age 60.

Extreme weather conditions heighten cholera risks in settings like refugee camps

Runoff from sewage—exacerbated by situations like flooding or extreme rains—heightens this threat. Increasing temperatures also create the ideal conditions for the bacteria to reproduce, increasing transmission risks.

Improved 19th-century sanitation meant kids encountered polio later, with worse results

Almost all children likely used to contract poliovirus, but scientists suggest that when infants encountered it very early in life—due to poorer conditions and hygiene—they still had some maternal protection from pregnancy or through breastmilk, so the symptoms were more flu-like.

Adults usually have some immunity to HFM Disease—but can still spread it

In 2025, certain eastern states including Virginia and West Virginia reported a sizable uptick in their HFMD cases, particularly in their schools and daycare centers, though the reason for the larger outbreaks remains unknown. When adults or teens get the disease, their symptoms are usually mild or even asymptomatic. Still, they may pass the disease between people, too. (Some users may encounter a paywall.)

Roughly 1 in every 4,300 individuals in the US has mitochondrial disease

Roughly 1,000 to 4,000 kids are born with these conditions each year in the US though many of the diseases are fatal. Mitochondrial disorders often affect the organs that require the most energy, including the heart, brain, and muscles.

South Asia and sub-Saharan Africa are most at risk from falling pollinator numbers

Researchers at the Harvard T.H. Chan School of Public Health found that declines in pollinator populations would lead to higher rates of nutritional deficiencies, particularly in developing nations. Nations with large populations, such as China and India, would also be significantly impacted.

Pregnancy at older ages increases the chances of fetal abnormalities

Chromosomal irregularities are more likely at older maternal ages so genetic testing for a fetus of mothers-to-be at age 35 and older is often recommended. Conditions that can be screened for in utero include cystic fibrosis, Tay-Sachs disease, sickle cell disease, Down syndrome, spina bifida, Duchenne muscular dystrophy, and more.

Children are at increased risk of contracting swimmer's ear

Kids may be more likely to spend time at the pool so they have that water exposure. They also tend to have narrow ear canals, a prime location for water to get trapped. Frequently wearing earbuds or excessively trying to rid ears of earwax, however, can also increase the chances of painful swimmer's ear infections at any age.

HIV originated in Central and West Africa from a virus in chimpanzees

Researchers believe the virus crossed from chimpanzees to humans through bushmeat practices in the early 20th century, with genetic studies suggesting the most recent common ancestor of the HIV-1 M group, which is responsible for the global AIDS pandemic, emerged around 1910–1930 in Léopoldville (now Kinshasa) in the Belgian Congo.

Caucasians are at the greatest risk of developing macular degeneration

A 2016 analysis across ethnic groups found, among other things, that white participants had the highest incidence of the disease, followed by Chinese, Hispanic, and Black participants. This study did not answer why that may be the case.

Cultural norms about how to handle the bodies of loved ones in communities in West Africa have hampered Ebola responses.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

11 people died from firework injuries in the US in 2024.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

The tragic Pulitzer Prize-winning image 'The Vulture and the Little Girl' (1993) generated controversy, raised concerns about ethics in photography, and eventually led to the photographer's death.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

The boiling temperature of water decreases with increasing elevation because the molecules need less energy to overcome the lower atmospheric pressure associated with thinner air.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

Use this calculator to find the dollar value of your mental load, from meal planning to coordinating after-school care for your children.

The US first hosted the World Cup in 1994, a tournament that lives in soccer infamy for its poor planning and the murder of Colombian player Andres Escobar, who'd accidentally scored on his own net.

In 2026, Finland was named the world's happiest country for the ninth consecutive year based on its wealth, social safety network, and high life expectancy, among other factors.

Children are now three times more likely to say they want to be a YouTuber when they grow up than an astronaut, with some even attending 'YouTube camps' that teach kids how to create content for the platform.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

The Russia-Ukraine conflict is the largest ground war in Europe since World War II in terms of casualties, forces mobilized, and displacement of civilians.

Electrical grids worldwide must double their power delivery capacity by 2050 to meet surging demand from AI and electric vehicles.

Poison ivy can cause rashes year-round since all parts of the plant contain urushiol, the oil that triggers our allergic response.

Take a 3D tour of the Hajj, Islam's annual pilgrimage to Mecca, undertaken by over 1.5 million Muslims.

El Niño, Spanish for 'the boy,' was named after Jesus Christ because the phenomenon resembled the weather changes observed around Christmastime.

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight