Tardigrades can survive up to 3,000 times more radiation than humans thanks to Dsup—a damage-suppression protein.

The damage suppressor protein, which is exclusively found in tardigrades, has also been modeled as coating DNA and shielding it from radiation and the toxic byproducts of radiation damage. Dsup may become a fundamental ingredient in future DNA storage technologies.

Researchers have attempted to create more drought-resistant crops by introducing proteins that help protect tardigrades in their dehydrated tun state. The proteins’ ability to stabilize molecular degradation may allow scientists to develop refrigeration-free storage for vaccines, insulin, and blood.

Although often considered indestructible, scientists observed these creatures could endure temperatures near 150°C for only a few minutes in their tun state. Outside this state, only half the samples in a Danish study survived 37.1 degrees Celsius (98 degrees Fahrenheit) for 24 hours, making tardigrades extremotolerant rather than extremophiles.

A 2007 mission launched several species into low-Earth orbit, exposing them to microgravity in temperature-controlled modules. Survivability rates were high for microgravity exposure alone, but plummeted when combined with exposure to the full UV spectrum and the vacuum of space.

Despite being known as water bears, these microscopic creatures can shut down their metabolism when entering cryptobiosis, squeezing more than 95% of the water from their bodies. In this tun state, tardigrades can even survive the vacuum of space.

By expelling most of the water from their bodies, water bears assume a state resembling a dried-up cyst and can withstand extreme environments, such as arid deserts. But in this state and these environments, tardigrades cannot grow, reproduce, or perform other functions associated with life, unlike extremophiles like dry-loving xerophiles.

Those fired from guns at speeds as high as 825 meters per second (1,845 mph) could be resuscitated after impact. Shock pressure from greater speeds tore apart the samples, suggesting they could not survive asteroid impacts if brought to Earth from outer space.

When a can of ground beef and pork spoiled despite attempts to sterilize it with gamma radiation, researcher Arthur Anderson isolated the bacteria in the food and discovered Deinococcus radiodurans. The polyextremophile has since been found on the walls of nuclear reactors and overcomes radiation damage through highly optimized DNA repair mechanisms.

In the case of radiation-induced distortions in a DNA strand, specialized proteins can cut out entire segments and rebuild them using the second strand as a complementary template. If both DNA strands are completely severed, proteins interlace undamaged DNA with the severed DNA and rebuild both using complementary base pairing.

Their physiology and size, which is even smaller in the tun state, allow them to be carried by the wind and latch onto moist surfaces. They have been found in ocean trenches approximately 5 kilometers deep and at altitudes of six kilometers in the Himalayas.

While avoiding predators, including other tardigrades, nematodes, snails, mites and some fungi, these organisms feed on decaying plant matter and cellular fluid, which they access by puncturing cell walls with their stylets—spear-like structures within their mouths.

As of 2024, three tardigrade fossils have been discovered, all preserved in amber. Analysis suggests different species of the organism existed over 500 million years ago, when marine heterotardigrades and freshwater terrestrial eutardigrades diverged.

Freshwater-bound eutardigrades live on mosses and lichens and are distinguished by variations in the shape and number of claws at the end of their legs. Marine heterotardigrades, which live on algae and deep-sea sediments, have been observed to possess feathers, inflatable appendages, and flagpole-like tails.

Outside the protective atmosphere of Earth, astronauts are constantly bombarded by radiation, which, among other dangers, increases the risk cancer. While those of us on Earth can mitigate the effects of similar radiation by limiting exposure,...

The damage can increase the risks of cancer, cataracts, heart disease, and other illnesses based on exposure times and intensities. Contaminated food, water, air, or soil from near nuclear accidents can further prolong one's exposure.

Several safety mechanisms failed during Anatoli Bugorski's inspection of malfunctioning equipment at the U-70 synchrotron, the Soviet Union's largest particle accelerator. Despite receiving as much as 600 times the lethal dose of radiation to the brain, he has shown no intellectual damage and worked until the age of 77.

In the lab, mice dosed with probiotics prior to inducing exertional heatstroke, had better cognitive outcomes. This evidence underscores the links between the gut microbiome and the brain, at least in rodents.

Large doses of ionizing radiation can damage the body within minutes, particularly in the bone marrow and inner layer of the digestive tract. Victims may briefly seem fine before rapidly deteriorating as immune failure, infection and organ collapse set in.

Rather than having a circulatory system, oxygen is directly absorbed through their skin and spreads through a fluid called hemolymph as tardigrades crawl. When molting to grow, they shed their outer skin and stylets—sharp mouth parts used to pierce prey—which are regrown in their salivary glands.

These arachnids can transmit more than a dozen diseases to humans, and they're very resilient: Some can survive extreme heat and cold, live for years without a blood meal, and even survive multiple days underwater.

Environmental factors like X-ray exposure may break a strand of DNA, but cells can use a sister strand to patch the damage. Scientists exploit this system by introducing custom DNA templates, which cells use instead to make repairs.

Although no organism has ever lost all its DNA, the destroying angel mushroom contains amatoxin, which disrupts DNA transcription and is known to cause death via liver and kidney failure in three days. Doxorubicin, which tangles DNA to disrupt cellular replication, compromises a person's immune system.

The eggs are laid in skin that has detached after molting. These species undergo sexual reproduction, but others reproduce asexually, with females producing clones from unfertilized eggs. Some hermaphrodite species have both male and female reproductive organs and can self-fertilize.

Tardigrade samples can be collected by gathering moss and submerging it in tap water for 24 hours. The moss should then be cut and drained with a mesh sieve, and the water should be collected. Samples are observable in the water between 10x and 40x magnifications.

The protein KRAS, mutated in many cancers, was deemed ‘undruggable’. Now scientists are hoping to save lives with a batch of new compounds that target it.

Daily exposure to radioactivity is common but occurs in low doses outside of locations near nuclear accidents like Chernobyl and Fukushima. Researchers have detected radiation in tuna, bananas, and the human body due to increasing instrumental sensitivity, not rising concentrations.

Possessing unique biochemicals that can detoxify extreme environments and resilience against the Martian surface that is lethal to humans, scientists are exploring whether colonies of these organisms can transform small areas of the Red Planet into future habitats for humans. Extremophiles may also be best equipped to serve as microscopic factories for the fabrication of essential polymers.

Within the area—roughly the size of Yosemite National Park—animals such as wolves, bears, and feral dogs descended from the pets left behind have gradually adapted to low-level radiation. Eastern tree frogs in the area have darker skin than usual, which may have helped protect them from ionizing radiation.

A new space-adapted bacteria species, Niallia tiangongensis, was discovered on China's Tiangong space station. The bacteria display a heightened oxidative stress response and unique biofilm-forming abilities that assist them in healing from to radiation-based damage.

In 2019, Israel’s Beresheet probe, which contained tardigrades in a cryptobiotic state, underwent a gyroscopic failure when attempting to land. If they survived the crash, the tardigrades may have spread across the lunar surface, raising ethical concerns about planetary contamination.

Discovered in the 1980s, this creature has been dubbed the "immortal jellyfish" for its ability to revert from medusa to polyp form and back, preventing it from dying of old age. However, the jellyfish remains prey to fish and turtles and is defenseless to sea slugs as a polyp.

Their discoveries of polonium and radium involved ongoing exposure to radioactive materials before shielding technology was developed. Their notebooks, furniture, and other belongings remain radioactive today, requiring researchers to sign a waiver and wear protective clothing to access.

While investigating samples taken from within and around the hot springs at Yellowstone National Park, microbiologist Thomas Brock discovered Thermus aquaticus, a microorganism that thrived in hot water. It contained an enzyme called Taq polymerase, a critical molecule in polymerase chain reaction—a molecular photocopier that amplifies genetic signals to improve medical diagnostics.

When electrons are accelerated in the loop, they produce intense X-rays that can reveal properties of a sample struck by them, just as X-rays can be used to show bone structure in humans. Studying the reflected light from fossils can uncover the presence of known pigmentation compounds.

Rather than recovering a genetic sample of a lost species and editing it with that of living creature—as has been depicted in science fiction—scientists begin with living cells from close genetic relatives and use tools like CRISPR to swap in extinct versions of specific traits to create new hybrid species.

Through gene editing and the deployment of artificial cells, scientists can leverage learnings from the genetic sequencing of animals with known resistances to protect endangered species. Gene editing of certain species, such as mosquitoes, can also reduce their ability to spread diseases like malaria between humans.

Studies of dinosaur footprints alongside ice-deposited rock fragments indicate that early dinosaurs adapted to cold weather before the volcanic winters of the Triassic-Jurassic extinction event. These geological events helped dinosaurs to flourish by wiping out their amphibious competitors.

Ionizing radiation produced by elements such as uranium, polonium, and radium can damage living things, but the trace amounts found in the museum objects that Marie Curie once touched have been largely decontaminated, with more dangerous items stored in protective, lead-lined containers.