Tardigrades can survive in a dehydrated state for decades

Despite being known as water bears, these microscopic creatures can shut down their metabolism when entering cryptobiosis, squeezing more than 95% of the water from their bodies. In this tun state, tardigrades can even survive the vacuum of space.

Extreme temperature resilience appears to be temporary for tardigrades

Although often considered indestructible, scientists observed these creatures could endure temperatures near 150°C for only a few minutes in their tun state. Outside this state, only half the samples in a Danish study survived 37.1 degrees Celsius (98 degrees Fahrenheit) for 24 hours, making tardigrades extremotolerant rather than extremophiles.

Ballistic experiments show that tardigrades are unlikely to be an alien species

Those fired from guns at speeds as high as 825 meters per second (1,845 mph) could be resuscitated after impact. Shock pressure from greater speeds tore apart the samples, suggesting they could not survive asteroid impacts if brought to Earth from outer space.

Microgravity can alter the evolution of viruses and bacteria

Experiments conducted on the International Space Station have shown that microgravity environments can delay viral and bacterial infections and induce mutations not seen on Earth. These mutations could have implications for long-term space missions and human health and suggest space can serve as a testing ground for developing new therapeutic approaches.

Why tardigrades are a model extremotolerant species rather than an extremophile

By expelling most of the water from their bodies, water bears assume a state resembling a dried-up cyst and can withstand extreme environments, such as arid deserts. But in this state and these environments, tardigrades cannot grow, reproduce, or perform other functions associated with life, unlike extremophiles like dry-loving xerophiles.

Mold growth in space raises the hypothesis of life being brought to Earth

Panspermia suggests that life could be carried throughout the cosmos by asteroids, comets, and other objects, but it requires organisms that can withstand the extreme cold of space travel, stellar radiation, lack of water, and intense heat of planetary impacts. The discovery of mold on the International Space Station and experiments showing it can withstand radiation in outer space-like conditions increase the plausibility of the hypothesis.

There are no established minimum fitness standards for spaceflight

Microgravity is known to cause arterial hardening, bone weakening, and other health issues, but the novelty of space tourism and the minimal exposure time for suborbital trips have limited the number of research studies. Many companies have participants sign extensive waivers to bypass the requirement of specific medical standards.

Tardigrades average about half a millimeter in size, with rear legs used for grasping

Their physiology and size, which is even smaller in the tun state, allow them to be carried by the wind and latch onto moist surfaces. They have been found in ocean trenches approximately 5 kilometers deep and at altitudes of six kilometers in the Himalayas.

Civilians on short-term spaceflights can experience long-term astronaut health impacts

A collection of 44 studies—primarily based on data from a 2021 tourist trip to low Earth orbit—identified immune system disruption and some kidney damage in tourists, with women appearing to recover from space travel faster than men. Return trips from Mars may require human travelers to be on dialysis.

A lunar probe’s crash landing may have spilled tardigrades onto the moon

In 2019, Israel’s Beresheet probe, which contained tardigrades in a cryptobiotic state, underwent a gyroscopic failure when attempting to land. If they survived the crash, the tardigrades may have spread across the lunar surface, raising ethical concerns about planetary contamination.

Muted smell and taste in microgravity complicate meal enjoyment

Astronauts primarily consume freeze-dried meals, which are rehydrated with water recycled from urine and perspiration, directly from bags. Condiments and select cultural items from crew members can enhance the meal experience by boosting flavor. Many individuals report experiencing "food fatigue" due to a lack of fresh produce, limited menu variety, and lingering scents.

Tardigrades typically live between 3 and 30 months

While avoiding predators, including other tardigrades, nematodes, snails, mites and some fungi, these organisms feed on decaying plant matter and cellular fluid, which they access by puncturing cell walls with their stylets—spear-like structures within their mouths.

About 1,500 species of tardigrades have been identified by their unique physiology

Freshwater-bound eutardigrades live on mosses and lichens and are distinguished by variations in the shape and number of claws at the end of their legs. Marine heterotardigrades, which live on algae and deep-sea sediments, have been observed to possess feathers, inflatable appendages, and flagpole-like tails.

Drugs in space: the pharmacy orbiting the Earth

Researchers are developing pharmaceutical solutions for astronauts, whose bodies may not respond the same way in space as they would on Earth. Similar to how microgravity causes changes to astronaut physiology, the environmental shift enables new...

Extremophiles were likely to have been Earth's first, and are expected to be its last, organisms

Their ability to survive in an enormous range of environmental conditions, including some resembling what has been modeled to have existed relatively shortly after Earth's formation, makes them the leading candidates for enduring the increasing solar intensity and the subsequent effects (e.g., zero-oxygen atmosphere, evaporated oceans) expected in the coming billions of years.

Protecting astronauts against space radiation

Outside the protective atmosphere of Earth, astronauts are constantly bombarded by radiation, which, among other dangers, increases the risk cancer. While those of us on Earth can mitigate the effects of similar radiation by limiting exposure,...

NASA uses extreme Earth environments to prepare for space exploration

Analog missions in volcanic terrains and craters mimic Martian and lunar environments. Crew members operating in these missions, including at sites in Utah, Nevada, Arizona, and Hawai'i, test suits and specialized space instruments under simulated conditions.

The inhabitability of the Martian environment presents significant colonization risks

Terraforming the thin atmosphere, toxic dust, extreme cold, and lack of magnetic field is infeasible, given limitations to the size of what can be sent to Mars. NASA and SpaceX are instead exploring creating underground shelters.

Tardigrades’ intrinsically disordered proteins may help preserve biological matter

Researchers have attempted to create more drought-resistant crops by introducing proteins that help protect tardigrades in their dehydrated tun state. The proteins’ ability to stabilize molecular degradation may allow scientists to develop refrigeration-free storage for vaccines, insulin, and blood.

Watch tardigrade samples under an optical microscope

Tardigrade samples can be collected by gathering moss and submerging it in tap water for 24 hours. The moss should then be cut and drained with a mesh sieve, and the water should be collected. Samples are observable in the water between 10x and 40x magnifications.

Prolonged space travel significantly impacts multiple human body systems

Astronauts can lose 20% of their muscle mass after two weeks and 10% of their bone mass after six months in space. Decreased sharpness of eyesight and changes in neural connectivity, brain structure and gut bacteria have also been observed.

Why extremophiles may play an important role in terraforming Mars

Possessing unique biochemicals that can detoxify extreme environments and resilience against the Martian surface that is lethal to humans, scientists are exploring whether colonies of these organisms can transform small areas of the Red Planet into future habitats for humans. Extremophiles may also be best equipped to serve as microscopic factories for the fabrication of essential polymers.

Fossils suggest tardigrades developed cryptobiosis more than 180 million years ago

As of 2024, three tardigrade fossils have been discovered, all preserved in amber. Analysis suggests different species of the organism existed over 500 million years ago, when marine heterotardigrades and freshwater terrestrial eutardigrades diverged. (Some readers may experience a paywall.)

Research suggests the cleanliness of the ISS may make astronauts unhealthy

The International Space Station's sterile conditions deprive astronauts of the opportunity to strengthen their immune systems through microbial exposure. To address this problem, future missions may use probiotic-based cleaners and foster diverse microbes in space habitats.

Microgravity environments reduce muscle mass and bone density

Muscles that assist with balance and resistance to gravity are not subjected to their usual workload on the International Space Station. See the type of exercises that astronauts must complete for roughly two hours daily, and learn why these movements are necessary to preserve astronauts' muscles, bones, and cardiovascular health.

Five hazards of human spaceflight

From space radiation to isolation, humans struggle when it comes to traveling and living in space. What does this mean for long-term spaceflight? This hour-long podcast episode attempts to answer that question while detailing five major spaceflight hazards.

Explore a gallery of tardigrades

Although sometimes called moss piglets, tardigrades are most often white or clear with some dark pigments. Tardigrades only move by crawling, not swimming, and depictions of organisms with caved-in heads or other coloration result from sample preparation for microscopes.

About 10% of the radiation people are exposed to each year comes from outer space, with higher percentages for those living at higher elevations or who fly often.

How spoiled meat helped uncover a bacterium that can survive the vacuum of space

When a can of ground beef and pork spoiled despite attempts to sterilize it with gamma radiation, researcher Arthur Anderson isolated the bacteria in the food and discovered Deinococcus radiodurans. The polyextremophile has since been found on the walls of nuclear reactors and overcomes radiation damage through highly optimized DNA repair mechanisms.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Why the existence of extremophiles greatly improves the odds of life beyond Earth

The conditions for life have long been thought to include liquid water, an energy source, and the essential elements for organic molecules within environments on or near Earth's surface. However, because extremophiles thrive in far more inhospitable environments, astronomers now analyze exoplanets whose characteristics indicate environments that fall within a broader range of possibilities when searching for signs of extraterrestrial life.

If the sun disappeared, we would not know about it for 8 minutes and 20 seconds, at which point the Earth would suddenly move in a straight line on its way out of the solar system.

Watch what it’s like to spend a day on the International Space Station

Microgravity makes personal care more complex on the International Space Station, where stray, floating materials must be captured to prevent them from entering vents and clogging filtration vents. No-rinse shampoo, water pouches, and other strategies help minimize obstructions.

Astronauts follow strict schedules to mimic Earth days and stay healthy in space

Experiencing 15 sunrises and sunsets a day while aboard the International Space Station, visitors preserve their circadian rhythms and mental health with fixed timetables. Astronauts have described sleep as living in a vacuum cleaner due to ongoing air filtration.

It is impossible for astronauts to burp in space

Due to Earth's gravity, liquids and solids sink in our digestive system, while gases rise, allowing them to be forced back up the esophagus to be expelled through burping. In the microgravity environment of the International Space Station, burping would result in vomiting if it were possible.

The Russian Federal Space Agency enabled the first space tourism journey

NASA refused to take Dennis Tito, who had no formal training as an astronaut, up to the International Space Station. Instead, the American engineer and entrepreneur traveled aboard the Soyuz TM-32 mission and described the initial experience of microgravity after engine shut-off as the "most spectacular" part of the flight.

Dsup protects DNA from radiation up to 3,000 times the tolerable human dose

A key component of a tardigrade’s biochemical toolkit, the damage suppressor protein is produced and binds to DNA molecules when the animal enters its dormant tun state. Dsup has provided a 50% reduction in double-strand DNA breaks in mice after exposure to X-rays.