Large animals like giraffes and elephants have evolved unique cancer defenses.

Cancer is a group of diseases characterized by the uncontrolled growth of abnormal, mutated cells that can spread throughout the body.

The immune system is in a constant fight to detect and eliminate cellular mutations.

Low cell division rates in heart cells make heart cancer particularly rare

The heart's location in the chest also offers protection from external cancer-causing factors. The disease affects about 3 in every 10,000 people, though most cases arise from metastasis from other body parts.

The earliest evidence of cancer was found in a 1.7-million-year-old fossil—discovered in the toe of an ancestor of modern-day humans.

There are hundreds of subtypes of cancer, making a universal cure nearly impossible.

Lung cancer advances are making a big difference

Lung cancer deaths are declining faster than new cases due to advances in treatment. The progress illustrates what is possible, even for a cancer that has long had a poor prognosis.

Cancer is typically broken down into four stages influenced by tumor size, the presence of cancerous cells in the lymph nodes, and the extent to which the malignancy has spread to other organs in the body.

How does cancer spread through the body?

Cancer usually begins with one tumor, but it can spread to other organs if not removed. This video breaks down how cancer moves to these new areas and why some organs are more likely to get infected than others.

Searching for the history of cancer in ancient human bones

Nestled under archaeology lies bioarchaeology, which involves the study of bones, human or animal. This subfield recently birthed another field of study: paleo-oncology. Paleo-oncology looks for cancer and related biomarkers in bioarchaeological remains. This TED article explains how this nascent multidisciplinary field challenges the idea that cancer is modern.

Why don't we all have cancer?

The creation of a single cell produces 120,000 genetic mutations that can lead to cancer. This video investigates how our bodies proofread and autocorrect those mistakes.

Combining two cancer drugs increased the life space of mice by 30%

A study shows trametinib and rapamycin, two drugs used for cancer treatment in humans, increased mouse lifespan when used together. The medications delayed the onset of cancer and reduced chronic inflammation, results that will be explored in future research.

Six pigeons were trained to detect cancer from looking at CT scans—now that work is the basis for training new AI medical tools.

About 40% of cancer cases are linked to preventable risk factors

Maintaining a healthy weight, engaging in regular physical activity, and consuming a balanced diet can lower cancer risk. Research indicates that about 40% of US cancer cases are linked to preventable factors, including poor diet and inactivity. Understanding these mechanisms empowers individuals to adopt healthier lifestyles for cancer prevention.

How race science influences breast cancer research

Despite researchers' and physicians' pushback, race is still used in studies and clinics to categorize human differences in health conditions and treatment responses. This article explores how race has influenced breast cancer research. Considering race as a factor in cancer research, diagnosis, and treatment can lead to racial inequalities. Sociocultural factors, including food access and air pollution, greatly influence health outcomes.

Explore global maps of cancer prevalence, with incidences that reflect various risk factors, including smoking rates, HPV infections, sunscreen use, and alcohol consumption.

Cancer rates are on the rise among GenXers and Millennials

Cancer rates are rising among Gen X and Millennials, with more cancer diagnoses being made in their 30s and 40s than previous generations. Factors such as prenatal exposures, environmental toxins, and lifestyle choices may contribute to this trend. Memorial Sloan Kettering Cancer Center's experts discuss these issues, exploring how these insights could reshape cancer risk understanding.

Uncovering the evolution of history's largest dinosaurs

This article details how sauropods—the dinosaurs that Little Foot would call longnecks—repeatedly evolved to attain such colossal sizes, towering over other land critters, including tyrannosaurs and mammoths. Sauropods were giant, long-necked...

Tigers emerged much earlier as a species than lions

Both lions and tigers are iconic big cats known for their size and power, but they remain distinct species. Beyond just looking different, they can exhibit very different behaviors. For example, tigers are significantly less social than lions, who live in social matriarchal groups. Tigers and lions are unlikely to ever interact in the wild, but humans have artificially bred them in captivity, creating a "liger."

Air sacs and lightweight bones helped some dinosaurs grow to enormous sizes

After the Triassic extinctions, new species with birdlike anatomy evolved from smaller, early dinosaurs. This anatomy allowed for more efficient breathing and lighter skeletons, favoring the evolution of larger organisms.

mRNA vaccines alter immune response, not DNA, to combat diseases like cancer.

US cancer mortality rates have been falling for 25 years

The American Cancer Society's "Cancer Facts & Figures 2025" report provides comprehensive statistics on cancer incidence, mortality, and survival rates in the United States. Cancer rates in the US continued a long-running downward trend, driven primarily by a steep drop in lung cancers (mostly from a decrease in habitual smoking) and better preventative monitoring. This site leads to incredibly in-depth reports and slides on the current state of the fight against cancer.

Many cancers arise from genetic mutations inherited from your parents

These mutations may happen in response to environmental or lifestyle factors, or may be passed down through family members. Genetic testing can be important in catching certain family cancers early and ensuring patients receive the right treatment for their disease.

Advanced drugs are closing in on cancer's deadliest mutations

The protein KRAS, mutated in many cancers, was deemed ‘undruggable’. Now scientists are hoping to save lives with a batch of new compounds that target it.

A new type of immunotherapy focuses on healthy cells hijacked by tumors

Purdue University scientists are at work on a new cancer treatment that attacks immune system cells that feed and protect cancer cells rather than attacking them. The immunotherapy process promises to become a universal treatment for solid tumors. Thus far, the treatment has been tested and shown to work on human tumor cells in the laboratory and animal models.

Metastasis: When cancer cells begin to travel through the body

Metastatic cancer starts in one part of the body and moves to another over time. This is known as metastasis. Such cancers are much more harmful since they attack multiple parts of the body, adapting new metabolic changes to suit the various environments found throughout a body.

Prostate cancer is both manageable and the second-deadliest cancer for men

One in 44 men in the US will die from prostate cancer, while one in eight will be diagnosed with it. Commonly viewed as the safest cancer to have, screenings can save lives—but they can also cause complications for otherwise benign cases of the disease.

Evolution doesn't want you to see these animals

Invisibility is an oft-coveted superpower that many creatures throughout the animal kingdom have evolved to mimic through transparent camouflage. This article explores the science of this seemingly magical ability. The two critical ingredients in...

Women typically have more robust immune responses than men

This difference helps women better combat infectious diseases, but this more turbo-charged response may also make women more vulnerable to autoimmune diseases by potentially priming their immune systems to overreact to their own cells and tissues and label them as invaders that must be destroyed. Roughly 80% of American women have autoimmune conditions.

Cells become cancerous if checkpoints in the cell cycle are damaged

Before cells divide, a protein called p53 can halt the cell cycle if damaged DNA is identified, preventing the fault from propagating to daughter cells. If p53 and other tumor-suppressing molecules cannot function due to mutations or other instabilities, damage can accumulate over successive generations until nothing stops cells from dividing uncontrollably, creating tumors.

Using deep learning to analyze tumors

The explosive growth of life sciences data is driving artificial intelligence methods to gain traction in biology and medicine — including cancer research.

Timeline of cancer research milestones

While cancer remains incurable, there's been so much progress in its treatment over the last two decades. Nature provides an abridged history of milestones and major triumphs in cancer research and treatment. Start in the year 2000, and see how much has changed in the first quarter of the new millennium

The seven viruses that cause human cancers

Certain viruses have been linked to the development of human cancers. These viruses account for up to 20% of cancers worldwide, causing cancer by interacting with host proteins, proliferating within weak immune systems, and commandeering susceptible human cells. Unlike other viruses, human tumor viruses don't kill host cells, allowing them to establish persistent infections. The seven viruses include the Epstein-Barr Virus, the Human Papillomaviruses, and more.

South American lungfish has the largest animal genome, with 91 billion base pairs

This genome is 30 times larger than a human's due to significant amounts of "junk DNA" and jumping genes, or transposons. Transposons can jump or copy over to other parts of a genome and may aid adaptation.

Birds, rodents, monkeys, lizards, bats, apes, and livestock can all get malaria—just like humans.

Roughly 1 in 5 cancers are caused by viruses

About 20% of cancers are caused by viruses, with seven specific oncoviruses causing between 10% and 15% of cancers worldwide. These include human papillomavirus and hepatitis B and C viruses, which can lead to diseases such as cervical and liver cancer. Understanding the mechanisms of these viruses is crucial for prevention and treatment strategies.

How snake biology allows them to eat prey larger than they are

Possessing flexible skulls with elastic ligaments and unfused jaw bones, snakes can open their mouths to engulf much larger prey, and adjustable airways enable them to continue breathing while their teeth grip onto their food. Through slow digestion and specialized cells that decompose bones, some snakes can survive on a single large meal for over a year.

Immunotherapy focuses on boosting the immune system to fight cancer

The immune system detects and destroys abnormal cells, curbing the growth of many cancers. Immunotherapy works to boost the body’s immune system to target and kill cancer cells. There are many ways to accomplish this, including adaptive cell therapy, checkpoint inhibitors, vaccines, and monoclonal antibodies.

Human anatomy provides evidence for evolution

Throughout history, scientists have used anatomy to support the Theory of Evolution in three main ways. Homologous structures, or similar physical features in organisms that serve different functions, can help scientists understand common ancestors....

How does cancer actually kill someone?

While the emotional and physical tolls of cancer are often clear, the innerworkings of how cancer kills can be confusing — and terrifying to discuss. Here, oncologists explain how cancer can progress.

Animal-to-human pathogens constitute 75% of emerging infectious diseases

Zoonotic diseases encompass more than 200 diseases transmitted from animals to humans, wherein humans are usually accidental hosts. Ranging from rabies to HIV to monkeypox, this overview lists some of the most common viral threats.

Chemotherapy is a cocktail of powerful drugs that slows cancer by interfering with cell division.

Chronic inflammation can cause cellular damage and could lead to cancer

Over time, this cellular defense system can inadvertently damage cells and tissues when it's in this heightened alarm mode over a prolonged period. This occurs because, when immune cells are sent somewhere without a true target, they may attack healthy cells and tissues.

Breast, prostate, and lung cancer are the most common forms of cancer.

Vector-borne diseases kill more than 700,000 people globally each year—and are growing

The diseases with the greatest potential to spread widely aren't the ones that quickly kill human hosts. Instead, the best hosts or reservoirs for vector-borne diseases would be chronically ill over the long term, increasing the likelihood that the pathogen could be transmitted to others.

Mammals thrived under the feet of dinosaurs

An explosion of fossil finds reveals that ancient mammals evolved a wide variety of adaptations allowing them to exploit the skies, rivers and underground lairs.

Zoonotic diseases: Pathogens that jump from animals to humans

Such diseases may be caused by a variety of pathogens—viruses, bacteria, fungi, or parasites—and can originate in creatures ranging from ticks and mosquitoes to pigs and bats. Because they develop in animals and are often new to human immune systems, zoonotic diseases have severe consequences for public health.

In 2026, University of Cambridge researchers reported that a group of gut bacteria called CAG-170 may be a key marker of good health, occurring far more often in healthy individuals and less commonly in people with chronic diseases.

Bats have evolved to carry viruses without getting sick

Bats—the likely animal reservoir for diseases including Ebola and coronavirus—tolerate viruses without getting sick. The secret lies in evolutionary adaptations allowing bats to become the world’s only flying mammal and to thrive under immense physiological stressors.

Explore different living beings' sizes, from DNA to whales and the Pando clone

The Pando is actually a single organism in Utah, comprising more than 47,000 stems connected by a vast root system. It spans roughly 108 acres. Meanwhile, the average human stands at 5 feet and 7 inches. DNA, the genetic instructions for life, stands at a height of 3.5 nanometers.

Bats are uniquely suited to act as reservoirs of viruses.

Some of the deadliest diseases to jump from animals to humans originate in bat species. This rich visualization explores the diversity of bats and the factors that make them efficient vectors for harboring and transmitting disease, from their long lifespans to their migration patterns.