PET scans create images of the body by detecting light emitted from the annihilation of matter and antimatter, with the latter produced by custom chemicals containing radioactive atoms.

How radioactive isotopes are created and used for medical diagnostics

In particle accelerators, protons can be accelerated into other atoms to create radioactive isotopes, which can be attached to specific molecules to create radiotracers that are taken up by specific cells. Radiotracers can emit particles that produce light once they collide with an electron, and this light can be captured by a PET scanner to diagnose specific ailments.

Antimatter particles possess the same mass and spin as their normal particle counterparts, but possess an opposite charge and transform into pure energy upon colliding with normal matter.

Particle accelerators detect subatomic particles using millions of sensors

Calorimeters measure the energy of particles. Tracking devices can measure momentum and charge from the trajectory of particles, which is determined by recording tiny electrical signals. Time-of-flight detectors provide particle velocities directly and particle mass indirectly, giving physicists a suite of properties to compare with those of known matter.

Less common types of radioactive decay include emitting neutrons and antimatter

Through neutron emission, one or more neutrons are ejected from atoms that have far fewer protons. Neutrons can also be released by artificially inducing the fission, or separation, of a large atomic nucleus into smaller ones. During beta-plus decay, a positron—the antimatter version of an electron—is produced when a proton turns into a neutron.

Computed tomography scans use X-rays to create 3D internal images

Just as shadows can reveal the shape of obstacles blocking visible light, the donut-shaped CT scanner measures how X-rays are blocked, revealing the shape of bones, organs, tissue, and other matter along a cross-section. As it rotates, the scanner combines these cross-sections to build a model of the internal structure.

View summaries of the most common types of radioactive decay and their associated particles

The alpha particle has the strongest ability to ionize other atoms it strikes, but it also does not travel very far before colliding with something and being absorbed. Gamma particles—high-energy photons—do not interact with matter as easily and therefore possess the greatest penetrating power, though this also makes their ionizing potential the smallest.

Although they rely on radioactive elements to operate, everyday technologies such as electronic exit signs, some wristwatches, and smoke detectors are not dangerous, unless they are damaged and their radioactive material is inhaled or swallowed.

Particle accelerators have been used to reveal detailed ant anatomy

Using a synchrotron facility at the Karlsruhe Institute of Technology in Germany, a pair of X-ray beams swept across about 2,200 ant specimens to create over 200 terabytes of projection images from multiple angles. The images were compiled into micrometer-resolution 3D reconstructions of 792 species, which are freely accessible on the Antscan platform.

Cyclotrons move particles in spiral paths of increasing radius

After particles are injected into the center of the device, an alternating electric field and a constant magnetic field energize the particles as they spiral outward toward a target. Cyclotrons are common in hospitals that perform molecular imaging, which relies on radioactive components that decay within hours.

The average banana produces one positron—the antimatter counterpart to an electron—every 75 minutes as its trace amounts of radioactive potassium decay.

At CERN's Antimatter Factory, researchers create and guide antiprotons and antielectrons together to form antihydrogen, and all these antiparticles are analyzed to help scientists study the behavior of antimatter.

Before 1932, when particle accelerators were first used for nuclear research, scientists relied on naturally radioactive substances to advance their understanding of the atomic nucleus.

Antimatter can be created from dark lightning—high-energy light emitted by deflected electrons after they are accelerated to near the speed of light by thunderstorms.

Learn about the applications of radioactivity in medical, academic, and industrial settings

Besides their use for radiometric dating by archaeologists and researchers at museums and universities, radioactive materials are used in sensors that help track ocean currents and analyze pollution, soil, and petroleum products. Radioisotope-based sensors also help measure air in ice cream and prevent spillovers when soda bottles are filled in factories.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second.

Particle beams can be used to alter the surface properties of artificial joints

Surface hardening and embedding specific elements or coatings can improve the biocompatibility and bone tissue integration of these implants. Particle accelerators are significant sources of the radioisotopes needed in medical diagnostics, and microwave linear accelerators are used in the majority of cancer irradiation treatments.

Learn about the 'Goldilocks' of radioisotopes, which can help attack hard-to-treat cancers

Actinium-225 can be attached to a molecule that binds to cancer antigens, helping it target specific cancers in the body. It emits alpha particles that can damage DNA but do not penetrate deeply, confining the damage to nearby cancer cells. However, annual global production of actinium-225 is less than a grain of sand.

Antimatter was discovered by examining debris from collisions between atmospheric gases and cosmic rays—high-energy matter particles from space.

More than 97% of the world's particle accelerators are used for commercial purposes

Only a few hundred of the over 30,000 particle accelerators worldwide are used for research. Most are involved in medical imaging and treatment, food sterilization, semiconductor processing, cargo screening, and radioisotope production. They're also used to modify the properties of polymers.

In 1997, the Compton Gamma Ray Observatory identified 'positron geysers'—fountains of antimatter particles—emerging from near the center of the Milky Way.

An overview of radioactivity, which can spontaneously change one element into another

Unstable atomic nuclei can transmute into a new element—an atom with a different number of protons—by emitting an alpha particle (two protons and two neutrons) or a beta particle (an electron). The electron can emerge from the nucleus when a neutron, which has no charge, suddenly transforms into a proton and an electron, thereby maintaining zero charge before and after the transformation, but altering the original element.

Airport security scanners use X-rays to infer baggage contents, with newer machines combining images taken at multiple angles and with various X-ray energies for improved threat detection.

Scientists can create movies of atomic and molecular phenomena using X-ray free-electron lasers, in which images are produced by matter being struck by high-intensity light created by accelerating electrons.

In an X-ray free-electron laser, electromagnetic fields are used to accelerate and move electrons in wiggling patterns, causing them to emit synchronized, high-energy X-rays. This resulting light beam can strike targets up to 120 times per second to create movies of changing molecular structures and phenomena.

Scientists can tag distinct proteins with fluorescent probes that emit different colors, allowing them to visualize multiple biochemical processes simultaneously.

How helium enables MRI machines to look inside organisms

By cooling the machine's magnets with liquid helium to extremely low temperatures, they can generate and maintain powerful magnetic fields that align the hydrogen atoms in living things to point toward a patient's head or feet. A radio pulse nudges these atoms, which realign and induce a measurable signal in nearby electrical coils. These signals are captured in slices and then stacked into a 3D reconstruction.

Can brain scans help with processing trauma?

MRIs and brain monitoring therapies are becoming increasingly popular for those looking to process trauma and address mental health conditions, including PTSD and depression. This article details how these therapies quantify mental health, giving users another way to measure and manage their mental and emotional needs through brain mapping and other methods.

View the periodic table of radioactive elements, and a list of each's most stable isotopes

Technetium is the lightest artificial radioactive element, which is produced primarily as a byproduct of nuclear fission. Several unstable isotopes are commercially available to medical professionals and scientists, despite their radioactivity risks.

Particle detection has evolved from cloud and bubble chambers to digital 3D displays

As invisible particles passed through cloud and bubble chambers, they disrupted supersaturated vapor and superheated liquid, respectively, creating trails that served as proxies for cosmic rays. The transition from photographed events to digital sensors enhanced data collection and accuracy.

How do brain scans work?

There's only one thing in our solar system sophisticated enough to study itself: the human brain. But this self-investigation is challenging because a living brain is shielded by skull, swaddled in tissue, and made up of billions of tiny cells. How do we study living brains without harming their owners? Two experts explain how the various techniques like EEGs, fMRIs, and PETs work in this TedEd talk.

Depictions of antimatter in science fiction include misleading portrayals of it coming from parallel universes, being mined from asteroids, and serving as a workable laser beam.

View the most expensive materials on Earth, led by antimatter and other elements forged in particle accelerators.

Particles produced in cosmic ray showers that would normally decay long before they reach Earth's surface are observed in ground-based detectors because they experience time more slowly when moving near the speed of light—a phenomenon predicted by special relativity.

Cathode-ray tube televisions are examples of electron accelerators

CRT TVs work by converting electricity into heat, which causes electrons to be emitted from the rear of the device in three beams responsible for the colors red, green, and blue. Electromagnets direct electrons to phosphor molecules on the screen, which emit light and illuminate the pixels.

What are pulsars?

Pulsars are neutron stars created as part of stellar evolution and emit radiation beams visible from Earth. These beams pulse like a lighthouse's light due to the star's rotation, creating periodic high-energy emissions. Pulsars were first discovered as radio sources; it was also discovered they emit gamma rays. NASA uses its Fermi Gamma-ray Space Telescope to retrieve and analyze data from pulsars.

Particle accelerators propel matter toward small targets at high speed

Devices like cathode-ray tube televisions were once basic particle accelerators, but modern ones, such as the Large Hadron Collider, use massive magnetic fields and circular tunnels to achieve energies high enough to recreate the conditions just after the big bang.

If they could be built, antimatter drives, which run on energy released from the collision of matter and antimatter particles, would be the most efficient engines in existence.

Six pigeons were trained to detect cancer from looking at CT scans—now that work is the basis for training new AI medical tools.

A beam of neutrinos can be created by firing a beam of high-energy protons at a target to produce unstable particles that decay into neutrinos.

Build atomic nuclei to explore their instability and resulting radioactive decay

In this simulation, users can add protons and neutrons to create an atomic nucleus, view its half-life and decay options, and identify patterns in how specific combinations of particles create extremely stable nuclei, from which the nuclear shell model of stability emerged.

In 2026, researchers successfully transported antimatter in a truck using a portable trap that employed electromagnetic fields to hold 92 antiprotons.

Simulate the decay of a radioactive substance to visualize its half-life

By definition, the half-life is the amount of time it takes for half of a radioactive sample to decay. With each half-life that has elapsed, half of the starting sample is left, leaving less to decay each time. This results in the number of undecayed atoms decreasing exponentially, with less stable substances having shorter half-lives and decreasing exponentially more rapidly.

Scientists can determine the age of rocks, fossils, and other ancient samples by measuring how many radioactive atoms in the sample have decayed, a process that occurs at precise, well-known rates.

Photons emitted via stimulated emission have identical characteristics

When confined to a pair of mirrors, a single photon passing a region of population-inverted atoms can produce a chain reaction of monochromatic light. This chain reaction amplifies the initial photon, from which lasers get their name: light amplification by stimulated emission of radiation.

Synchrotron radiation has revealed the fur color of creatures millions of years old

When electrons are accelerated in the loop, they produce intense X-rays that can reveal properties of a sample struck by them, just as X-rays can be used to show bone structure in humans. Studying the reflected light from fossils can uncover the presence of known pigmentation compounds.

The Curies developed a way to measure radioactivity in an old medical dissecting room

Despite lacking proper laboratory conditions, Marie and Pierre built an ionization chamber and a piezoelectric quartz electrometer to measure the amount of charged particles released by radiation, with a sensitivity of ten-trillionth of an ampere. Substances with different emission rates indicated different elements.

Antimatter was predicted to exist four years before it was observed, though the mathematics responsible for the prediction described it as matter with negative energy.

If particle accelerators did create black holes by packing tremendous energy into a small volume, then trillions would be created in Earth's atmosphere daily by cosmic rays.

Turning nuclear waste into cancer medications

This video explores Terrapower, a company transforming nuclear waste into lifesaving cancer treatments. This is accomplished through the production and use of Actinium 225, a rare isotope derived from thorium, which is used in targeted alpha therapy to treat cancer.

Simulate the impact of an antimatter bomb, which releases energy from the annihilation of matter with antimatter, around the world.

It may be possible to create dark matter in particle accelerators

In high-energy collisions, exotic forms of matter can be produced by directly converting energy into mass according to *E = mc*². Even though a dark matter particle would not be directly observable, its creation would result in unaccounted-for mass, which can be compared to potential dark matter candidates for indirect detection.