West Nile was reported in 47 states in 2025, with more than 1,400 people severely affected

US West Nile case numbers were up 40% in 2025, nationally

This surprising surge may be due to warmer temperatures and elevated rainfall—leading to the ideal conditions for mosquitoes to thrive and breed in standing water. Symptoms can be hard to recognize when the disease is mild—similar to a flu. But neurological complications can lead to hospitalization and be deadly.

Most cases of West Nile virus are asymptomatic in people

About 1 in 5 infected people develop symptoms from West Nile, including symptoms such as fatigue, head and body aches, and vomiting. But around 1% of patients develop severe complications such as encephalitis or meningitis, which can be life-threatening. Those who are most likely to become severely ill are people over age 60.

West Nile is named after the district in Uganda where it was first isolated from a patient

In 1937, scientists isolated the virus from a woman in the West Nile District of Uganda. It's since been detected in much of Africa, Eastern Europe, West Asia, the Middle East, and was first detected in US patients during an outbreak in 1999.

West Nile has been detected in at least 2 species of reptiles

Birds remain the main reservoir for the disease, but scientists have detected the virus across a wide range of species, including at least 48 mosquito species, over 320 bird species, more than 25 mammals, and two species of reptiles.

West Nile virus was detected in UK mosquitoes for the first time in 2023

Fragments of the virus were detected in mosquitoes that were being collected in Britain for the first time in 2023, but the UK government considers the overall risk to people to be low. As of spring 2026, there have never been detected locally-acquired cases of the disease.

There's no cure for West Nile virus—and infection can leave patients with permanent symptoms

This news story features Marie Heilman, a woman who became ill at age 40 from an infected mosquito bite in her yard. She says she was in a coma for 15 days, and though she woke up, she suffers from seizures, fatigue, vision issues, and has had two strokes.

Nearly 5,500 crows died during four months in 1999 from West Nile in NYC

Subsequent testing made clear the disease at that point was 100% fatal to crows. From 1999 to 2004, millions of birds died as West Nile spread across North America, but the virus fortunately became less virulent as it moved westward.

10 locally acquired malaria cases were reported in the US in 2023—a surprise

The cases, reported in Florida, Texas, Maryland, and Arkansas, broke a 20-year streak since there had been no reported locally acquired mosquito-transmitted malaria in the country since 2003, when there was a case in Florida.

Horses have four licensed West Nile vaccines—but humans have none

A major hurdle for West Nile vaccine development is the lack of a market for it since so many people are symptomatic for the infections. Still, a growing number of infections, including a 40% spike in 2025, may change that calculation.

Hear from a NYC public health official who led the first US investigation into West Nile

This podcast walks through the investigation into the first US outbreak of West Nile, and how the virus had never been seen in the Western Hemisphere. The official discusses how she thinks the origin of West Nile in the US may have been birds or other animals that were brought here illegally.

See the total number of Lyme cases per state in 2023

New York, Pennsylvania, and Massachusetts had the highest total number of Lyme disease cases in 2023. New York had more than 22,000 cases that year. Maine had one of the highest Lyme incidence rates of disease that year—213 per 100,000 people—but only 2,942 cases overall.

Scientists found that if cats in the lab ate infected rodents they could get West Nile

But beyond the lab setting there have been no known cases of cats or dogs contracting the virus this way. Instead, those animals have been sickened when an infected mosquito bit them—just as with human infection.

Zika virus shocked scientists because the mosquito-borne disease causes birth defects

This revelation, confirmed in 2016, marked the first time that a mosquito-borne disease was known to cause birth defects. Fetuses exposed to the Zika virus during pregnancy sometimes suffer from neurological complications and microcephaly, a small-headed condition associated with neurological development issues and impairment.

More than 20 mosquito-borne and tick-borne diseases are found in the US

Children, older adults, and people with compromised immune systems are at particular risk of poorer health outcomes from these diseases. But dog owners and outdoor enthusiasts are among those at particular risk of contracting these illnesses, which include Lyme disease, Zika, and the condition Alpha-gal Syndrome.

Rabies kills more than 50,000 worldwide each year

Rabies transmission to humans typically comes from an infected animal, and death was very common before recent protocols were developed (post-exposure prophylaxis). The virus is neurotropic, which means it has an affinity for nerve tissue, and moves quickly from broadly infecting the body to destroying the brain.

Wolbachia: the bacteria that could eliminate dengue fever

Dengue fever, transmitted by mosquitoes, kills more people annually than all types of natural disasters combined. However, mosquitoes that host Wolbachia bacterium have their ability to transmit the virus naturally suppressed, offering a route to eliminating nearly 25,000 deaths annually.

More than 4,000 people died from cholera in 2023

This global health threat sickened more than half a million people in 2023 and killed 4,007 people. That's a 71% increase in deaths as compared to a year earlier. (Report only offered in PDF format.)

CDC does not require docs to report hand, foot, and mouth cases which makes tracking difficult

Mid-Atlantic states saw a surge of hand, foot, and mouth disease in 2025 for as-yet unknown reasons. Virginia, Maryland, and New Jersey, reported elevated outbreak numbers in 2025 as compared to other recent years, but since the US Centers for Disease Control and Prevention does not require mandatory reporting of positive HFMD cases—unlike strictly notifiable diseases like measles—it's hard to truly know the extent of the outbreaks and how significant the caseload is as compared to prior years across the region or country.

From 1970 to 2017, invasive species have caused $1.28T in damage globally

The costliest species were the Asian tiger and yellow fever mosquitoes ($149B), which arrived in the US from Asia and sub-Saharan Africa, respectively. The bulk of their damage came from their transmission of diseases such as Zika, chikungunya, and dengue. (Some readers may experience a paywall.)

Visualizing the year in US tornadoes, 2024

Between January and November 2024, over 1,700 tornadoes were documented to have touched down in the US, a relatively high number (and similar to the numbers in 2004, 2008, and 2011). This map shows their location across the country to help capture the number.

Human records of influenza stretch back more than two millennia

Accounts of flu-like illness appear as early as 412 BCE, when Hippocrates described a sudden wave of cough and fever. Centuries of recurring outbreaks culminated in the first clearly documented pandemic in 1580, spreading from Asia into Europe and Africa.

Yellow fever sidelined more US troops than enemy fire during the Spanish-American War

The disease, transmitted by the Aedes aegypti mosquito, sickened more than 2,000 soldiers. Fewer than 400 American soldiers died in the 1898 war.

11 people died from firework injuries in the US in 2024.

Oral polio vaccines cause approximately 250 to 500 polio cases per year globally

Live, weakened polioviruses in the oral vaccine can very rarely mutate into a disease-causing form and lead to vaccine-associated paralytic poliomyelitis. This oral vaccine is not available in the United States.

See how Ebola tore through Guinea, Sierra Leone, and Liberia in 2014-2016.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

Fireworks-related ER visits in 2024 increased by 52% as compared to the prior year

In 2023, there were 9,700 such injuries, but the number was 14,700 in 2024, according to analysis from the Consumer Product Safety Commission. Personal use of fireworks grew significantly during the pandemic, in part due to cancellations of public display shows, and that use has apparently continued—and prompted more injuries. What's more, the Census Bureau indicates that firework imports increased by around 19% between 2023 and 2024.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

Swimmer's ear is America's most common waterborne illness

Federal government analysis of the roughly 7 million waterborne illness cases that occur annually in the US found that swimmer's ear comprises some 4.7 million, or 65%, of the annual waterborne illnesses and 20% of hospitalizations. Norovirus infection comes in second place.

View the ten deadliest tornadoes in US history.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

Between 10 million and 50 million people in the US develop rashes from poison ivy, poison sumac, and poison oak each year.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

Electrical grids worldwide must double their power delivery capacity by 2050 to meet surging demand from AI and electric vehicles.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

The Russia-Ukraine conflict is the largest ground war in Europe since World War II in casualties, forces mobilized, and displacement of civilians.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

44% of Americans say they pray at least once a day—discover how your state's religiosity stacks up against the rest of the country.

US intelligence allegedly pursued more than 600 schemes to assassinate Cuban revolutionary Fidel Castro.

Visualize the path of every solar eclipse from 1900 to 2099 and see what each looks like when observed from different locations on Earth.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Before the current East Wing ballroom project, only two White House renovations in the past 100 years cost more than $10M.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

El Niño, Spanish for 'the boy,' was named after Jesus Christ because the phenomenon resembled the weather changes observed around Christmastime.