Non-amputees can be tricked into thinking they have phantom limbs with rubber arm experiments.

Phantom limbs aren't just limited to limbs—there are phantom breasts, teeth, and more, and these sensations are often painful.

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

Phantom limb pain may often match the pain or contortion of the injury that led to the limb loss.

Learn how a doctor successfully treated a patient's phantom limb pain with a mirror, tricking his brain into thinking his still-present arm was the missing paralyzed left one.

Research suggests the brain maintains connections to lost limbs

Decades-old research suggested brain reorganization after amputations, but brain scans show unchanged limb representations. Phantom limb pain may result from such unchanged brain maps, which may enhance prosthetic limb control in brain-computer interface technology.

Readers thought the fictional Civil War vet George Dedlow, a character suffering from phantom limb pain in an 1866 story in The Atlantic, was real—and sent donations and stopped by the hospital to meet him.

Mind-controlled bionic arms use nerve implants to restore sensation and movement

Unlike traditional prosthetics that rely on surface electrodes or mechanical parts, this system uses implanted titanium and nerve-connected electrodes to enable a seamless brain-to-arm connection. Patients train in virtual reality with their implanted signals before using the physical prosthesis.

Amputees must navigate the challenging medical and economic aspects of limb support and replacement, but advances in technology and research may reduce these costs.

See what analysis of one man's amputated leg, donated to The Bone Museum, tells us about his otherwise invisible pain.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Listen to an amputee describe what it was like in the aftermath of his partial foot amputation and how his chronic, extreme pain fueled his depression and his decision to attempt to alleviate the pain with the radical surgery.

1 in 15 adults over age 40 experience phantom odors

This phenomenon was measured in a 2018 study that examined the prevalence and risk factors for phantom odor perception. Older adults were less likely to experience these phantom odors as they age, just as their overall sense of smell declines. Women are more likely than men to perceive phantom odors.

Hacking the body for a future that didn't happen

Journalist Adi Robertson experimented with one of the most accessible biohacks: magnets. Having a tiny magnet in their right ring finger meant they could sense magnetic fields, attract small metal objects, and more. But magnets weaken over time, eroding this new sense. Such implants do more than offer a new way of interacting with the world, they also pose new complications, such as the inability to get an MRI.

Trauma-related amputations are primarily from falls, then car accidents and related traumas, followed by mechanical forces according to analysis based on global burden of disease data in 2017.

We can sense touch even through a tool

Research published in 2019 indicates that the same brain regions involved in sensing touch on the body also process it when humans use a tool to do the touching. Essentially, it's acting as a sensory extension of the body. (Some users may experience a paywall.)

Some scientists argue NDEs are constructed by the brain, not actually experienced

Despite the powerful memories associated with NDEs, scientists question the idea that the experiences prove consciousness endures after death, opting instead to find physiological explanations for common reports of out-of-body experiences, euphoric and lucid thinking, and more.

Blindfolded people could identify objects by touch alone a week after encountering them

These touch memories are more complex and durable than previously thought. In research published in 2018, blindfolded volunteers touched over 150 household objects for about 10 seconds each, and afterward correctly identified the objects more than 90 percent of the time when presented with the object and a similar one. Participants still knew most of the objects a week later with about 85 percent accuracy. (Some users may experience a paywall.)

Prehistoric hunter-gatherers performed amputations and appear to have provided post-op care, according to analysis of a recent fossil discovery from almost 31,000 years ago.

How does the body know where it is in space?

Close your eyes and touch your nose. How did you know where your nose was? How could you tell where your hand was? That's proprioception, the sense that keeps your brain apprised of the body's position and movement. This article explains how this sense works, what happens when people don't have it, and what we know about it.

Leprosy doesn't cause fingers or toes to fall off

The nerve damage that results from infection sometimes causes loss of feeling in extremities so injuries like cuts or burns may be missed. In such cases, resulting infections can lead to digit loss. Fingers or toes can also appear to shorten with this disease because nerve damage can sometimes make muscles in fingers and toes so weak that they're reabsorbed by the body.

Limb regeneration research may lead to treatments for arthritis

For scientists pursuing the cure for arthritis, the holy grail of discoveries lies in how to regrow healthy cartilage inside human joints. While this feat has so far resisted our best scientific attempts, there are plenty of other human tissues—such as the liver and fingertips—that will successfully regenerate.

Researchers have investigated the benefits of extreme pain rituals, exploring how and why we engage in these events when humans generally naturally avoid pain and perceive it as a negative experience.

Prosthetics and orthotics have been 3D printed to improve the lives of animals

Shells for hermit crabs, wheelchairs for guinea pigs and dogs, and horseshoes for improved running performance have been created using 3D printers. Other artificial body parts made using this technology include a jaw for a loggerhead turtle, a beak for a toucan, and a tail for an American alligator.

There are at least 6 fascinating examples of mind-controlling parasites

Parasitic organisms—including flatworms and barnacles, not just fungi—can modify animal behavior. They can give rise to dancing fish, pulsating snails, suicidal rats, and more. Though some of these pathogens can sicken humans, there is no strong evidence that any can control human behavior.

A stand-in 'nose' may help people with anosmia to smell certain odors

In a 2025 paper, researchers reported they'd created a proof-of-concept device that bypasses typical olfactory pathways and instead exploits an alternative—the trigeminal nerve in the nose—to detect a few strong scents. The nerve typically helps detect the temperature of inhaled air or the presence of irritants. (Some users may experience a paywall.)

Misfired motor signals may explain why many people with schizophrenia hear voices

Up to 80% of schizophrenia patients may have auditory hallucinations. Recent research concluded that this symptom may be from misfired motor signals that feed into each other, essentially failing to suppress certain sensory neural activities and that resulting overexcitment fuels hallucinations. The finding suggests that, one day, magnetic pulses might be used to stimulate specific nerves to better regulate the errant signals and reduce or stop hallucinations. (Some users may encounter a paywall.)

Individuals with synesthesia experience involuntarily overlapping sensations

Tasting words or seeing colors in music results from the brain retaining extrasensory connections from infancy. While most lose these neural pathways during development, about 4% of people are synesthetes, maintaining them without realizing it's unusual.

Some medical schools have phased out human cadavers for digital alternatives

AI-based anatomy tools and digital cadavers are increasingly used to teach students, bypassing the ethical and consent concerns around the use of real bodies. Digital cadavers have also become less expensive than real ones, though the tactile and sensory experiences of real dissection may be irreplaceable.

A researcher thinks she knows why people keep touching museum exhibits

A museologist who studied unauthorized touch at the British Museum concluded that people may feel it's difficult to learn about things "unless you handle them" and that people are trying to connect with the past, viscerally. Her work has included interviewing British Museum visitors who committed unauthorized touches and spending extensive periods observing people touching prohibited items across 2004 and 2005.

Some theorize that horror's artifice turns fear into enjoyment

The “excitation transfer theory” suggests that the unpleasant feelings a jump scare might elicit (like shortness of breath) are quickly relieved when the audience member remembers what they’re witnessing is fake.

The Lazarus Effect is when a heart begins beating on its own after declared death

Formally called autoresuscitation, this rare phenomenon occurs when someone is declared dead following a cardiac arrest but their heart beats again without help—making it seem like the person came back to life. Doctors don't know the exact cause.

Thomas Edison, eager to communicate with ghosts, tinkered with an apparatus called the 'spirit phone'

The inventor was interested in developing a scientific method for communicating with the dead. He was not interested, though, in the occult figures who believed the dead could be reached through Spiritualism, which he found childish. He believed those kinds of people "permit themselves to become, in a sense, hypnotized into thinking that their imaginings are actualities."

Lee Spencer, a single-leg amputee, broke the world record when he rowed solo and unsupported across the Atlantic Ocean in 2019.

Firework or sparkler burns can have large effects on our hands' range of motion

Dr. Erin Miller, a hand surgeon at Harborview Medical Center in Seattle, describes the range of injuries she's seen from firework injuries in this 2020 video. The damage includes loss of hands, fingers, and tips of fingers. Miller describes how in a recent year she was on-call during the week of the Fourth, and in just five days she saw 30 cases and had to amputate 42 fingers because of fireworks injuries.

Audio and visual cues from "Titanic," Pink Floyd, and more can provoke goose bumps

These audio and visual snippets have been used in research studies to elicit goose bumps.

Human teleportation through quantum principles raises questions about identity

Through quantum entanglement, particles have been "teleported" by measuring their state in one location and effectively transferring that state to a new location. Doing so for the particles that make up humans would destroy the state of the original particles, killing the person, and effectively creating a clone.

Why 'spacing out' or dissociating may help reduce trauma awareness

Dissociation may have developed as a defense mechanism in the brain to help navigate intense emotional or physical situations by providing out-of-body experiences that put distance between the mind and the environment. However, in about 1.1% and 1.5% percent of the general population, a severe form of this separation can produce alternate identities, or alters.

Optical illusions were a key component in animating the Muppets

Despite being fairly typical puppets, Jim Henson's Muppets often ventured out into the real world without any apparent humans controlling them. That's thanks to several ingenious optical illusions devised by Henson and his partners, including well-placed mirrors, platformed sets, and remote-controlled puppeting.

Brain conditions and surgery can cause some individuals to feel no fear

Fear is a survival mechanism that originates in the brain's amygdala, triggering the body's fight-or-flight response. However, in modern society, without the same natural dangers, fear can lead to anxiety and mental health issues when unnecessarily triggered. Understanding individuals without fear may help identify new methods to treat anxiety disorders.

Everything you know about Phineas Gage is wrong

A stray spark sent a 3.5-foot-long, 1.25-inch thick iron rod through the brain of foreman Phineas Gage in 1848, creating a scientific case that has attracted onlookers for nearly two centuries. His life reportedly soon spiraled out of control, with his behavior tending toward selfishness and chaos. Evidence of these changes is far less common, with Gage's story bloated by fabrication, scientific prejudice, and artistic license.

We may be using Q-tips in our ears—even when we shouldn't—because they can stimulate pleasure nerves

People continue to use Q-tips inside their ears even though we know it's risky. Some clinicians suggest that beyond the desire to get water out, this may be because the nerve bundle called the vagus nerve, which spans from the brain to the large intestine, can be stimulated that way, causing a pleasurable sensation in other body parts including the heart, belly, or genitals.

Why do we sometimes jolt awake before falling asleep?

Around 70% of people are estimated to experience the sensation of falling and jerking awake right as they're about to drift to sleep. That mysterious phenomenon is called hypnic jerking. As common as it is, hypnotic jerking remains disconcerting and hard to explain. While we don't yet have clear answers, peruse this article in Popular Science for some possible explanations as to why this happens.

The art of 'undiscovering' phantom islands

Centuries of maps include islands and isles that appear to only exist on atlases. This article explores the discovery and "undiscovery" of such landscapes, which still persist despite modern technology. As recently as 2012, Google Maps showed an...

Touch deprivation can heighten anxiety and depression

Pacinian Corpuscles are pressure receptors just under the skin that send signals to the vagus nerve in the brain—that's the cranial nerve which regulates involuntary actions like breathing, heart rate, and the general "fight or flight" response. Activating those receptors can slow the heart, decrease blood pressure, and lead to the release of oxytocin and cortisol. The absence of touch, conversely, can promote negative feelings.

Some Nobel laureates have expressed beliefs in pseudoscience after winning

Examples of the phenomenon, known as Nobelitis or Nobel disease, include promoting psychic research, harmful practices like eugenics, and seeing talking raccoons. Increased external pressures after a win and a greater spotlight may contribute to developing or exposing these beliefs.

Theoretically, you could lose a bunch of your organs and still survive

If surgeons removed organs including one of your lungs, a kidney, your spleen, appendix, tonsils, part of your liver, and even some of your reproductive organs you could still survive. Watch this animated video which dives into the organs you could conceivably live without.

Longer-duration space missions may amplify astronaut motion sickness

NASA is using the Kraken, a 50-foot-long, 100-ton US Navy research device, to simulate space motion sickness and vertigo and test possible recovery strategies, including testing out different, specific head movements. The Kraken, located at Wright-Patterson Air Force Base near Dayton, Ohio, can rotate participants at exposures of up to 3G.

Hysterical strength allows someone to lift a car off their child

When the body responds to an acute crisis—say a family member trapped under a car—people can sometimes perform seemingly superhuman feats. This is more than an urban legend: In 2012, a 22 year-old-woman lifted a vehicle off her father, and seven years earlier another man lifted a vehicle off a trapped cyclist. Yet scientists are still unraveling details about why this can occur.

Is life all about pleasure? Debating the Experience Machine

If you could plug into an Experience Machine that gave you total pleasure all the time, would you do it? Philosopher Robert Nozick thinks you wouldn't, using this as evidence against hedonism, the view that life is all about pleasure. Explore the nuances of the argument and counterarguments with this accessible article.

Former American President Abraham Lincoln is one of history’s most famous ghosts

Abraham Lincoln, Anne Boleyn, Pausanias, and the Maharajah Duleep Singh are just a few of the notable phantoms found around the world. Several White House occupants and visitors have claimed to see Lincoln, including Theodore Roosevelt, Grace Coolidge, and Winston Churchill.