Amputees must navigate the challenging medical and economic aspects of limb support and replacement, but advances in technology and research may reduce these costs.

Listen to how bionic limbs are reshaping what it means to live as an amputee in this award-winning 2022 podcast series covering the stories of two amputees who struggled with shortcomings in prosthetic technology.

Software subscriptions, licenses, and climate control systems add to 3D printing costs

Although the sharing of designs and reduced manual labor suggested the fabrication of prosthetics would be facilitated by 3D printing, particularly in developing regions, software and hardware requirements have posed hurdles to achieving this goal. While some insurance companies have refused to cover 3D-printed limbs, they are covered by Medicare.

Every 3.5 minutes in the US, a limb is amputated due to diabetes.

An experimental bionic knee has been directly integrated into the user's muscle and bone—not an external socket—marking a significant prosthetic advancement.

Trauma-related amputations are primarily from falls, then car accidents and related traumas, followed by mechanical forces according to analysis based on global burden of disease data in 2017.

See what analysis of one man's amputated leg, donated to The Bone Museum, tells us about his otherwise invisible pain.

Organ transplants can come with a price tag of more than $2M without insurance

According to 2025 report data that was graphically represented by Statista, average costs for organ transplants can be as steep as $2.3M for a double lung transplant and $1.9M for a heart. These figures are based on what was actually charged to insurance companies—not what individual patients paid. Following the actual transplant there are also additional costs associated with the procedure, including lifelong immunosuppressant drugs.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

Non-amputees can be tricked into thinking they have phantom limbs with rubber arm experiments.

Black patients are losing their limbs at a rate triple that of other groups due in large part to inequities in diabetes care and management.

Brain-reading devices are helping paralyzed people to touch

In clinical trials, implanted brain-computer interfaces are allowing dozens of individuals with paralysis to control prosthetics that are restoring a range of skills, including drinking coffee and feeding oneself. One area of related prosthetic research is creating a synthetic sense of touch—coupling the brain implant with pressure sensors in prosthetic robotic fingertips to enable an approximation of a sense of touch.

Prehistoric hunter-gatherers performed amputations and appear to have provided post-op care, according to analysis of a recent fossil discovery from almost 31,000 years ago.

Breaking down the knee's anatomy

The human knee is a remarkably complex structure carrying the full weight of the body throughout a person’s life while allowing a number of complex twists, flexes, and extensions. It's also one of the body's biggest weaknesses—the location of chronic pain and replacement surgeries for millions of Americans.

Limb regeneration research may lead to treatments for arthritis

For scientists pursuing the cure for arthritis, the holy grail of discoveries lies in how to regrow healthy cartilage inside human joints. While this feat has so far resisted our best scientific attempts, there are plenty of other human tissues—such as the liver and fingertips—that will successfully regenerate.

Implanted neurotechnology can leave users vulnerable when manufacturers go under

Despite providing relief from neurological conditions, patients are left stranded when the companies that make these devices shut down. The lack of regulation means patients often face technical failure, insurance battles, or risky surgeries to maintain their quality of life.

Prosthetics and orthotics have been 3D printed to improve the lives of animals

Shells for hermit crabs, wheelchairs for guinea pigs and dogs, and horseshoes for improved running performance have been created using 3D printers. Other artificial body parts made using this technology include a jaw for a loggerhead turtle, a beak for a toucan, and a tail for an American alligator.

Listen to an amputee describe what it was like in the aftermath of his partial foot amputation and how his chronic, extreme pain fueled his depression and his decision to attempt to alleviate the pain with the radical surgery.

Hear Aristotle Domingo, a bilateral amputee athlete, discuss his amputation journey.

Artificial wombs and preterm births: an overview

Scientists are working to create artificial wombs that would help preterm babies survive their early entry into the world. But how much help could this technology provide, and how much of a problem are preterm births? This article details some of...

736,900 cochlear implants had been implanted by 2020 worldwide

In the United States, roughly 118,100 devices had been implanted in adults by that point and 65,000 in children. These estimated figures come from the US Food and Drug Administration, which first approved cochlear implants for adults experiencing hearing loss in the mid-1980s, and collected reports from cochlear implant manufacturers approved for the US market.

Hear about life as an amputee and how mirror box therapy helped.

Palliative care physician BJ Miller describes his phantom limb pain and itching after losing both legs and half an arm in an accident. Mirror box therapy eventually helped him, alongside physical therapy. This podcast also features neuroscientist V.S. Ramachandran who explains how he developed mirror box therapy in the 1990s.

Each day, about 60 US pregnancies end in stillbirth

This online memorial for families who experienced the unexpected death of a fetus 20 weeks or older is the result of ProPublica reporters inviting 60 families to share their baby's name and answer some questions about their unfulfilled wishes for their children. About 21,000 babies are stillborn in the US annually. About the same number of children die in the US during their first year of life.

America's financial burden from dementia in 2025 was $781 billion

That figure, calculated by researchers at the University of Southern California, includes medical and long-term care costs, unpaid family and friend caretaking, lost productivity for patients and their families, and the economic loss in quality of life for patients and their families. In 2025, they estimate there were 5.6 million people living with dementia.

As of 2025, perfect synthetic replication of natural organs remains elusive

Advancements such as 3D printing muscles, performing vaginal reconstruction with colon tissue, and growing organs in a lab have shown promise, but artificial options and transplanting substitutions continue to exhibit functional and performance limitations compared to their natural equivalents.

Lee Spencer, a single-leg amputee, broke the world record when he rowed solo and unsupported across the Atlantic Ocean in 2019.

Some medical schools have phased out human cadavers for digital alternatives

AI-based anatomy tools and digital cadavers are increasingly used to teach students, bypassing the ethical and consent concerns around the use of real bodies. Digital cadavers have also become less expensive than real ones, though the tactile and sensory experiences of real dissection may be irreplaceable.

Medical professionals have experimented with using mixed reality headsets

Devices like the Apple Vision Pro have helped doctors develop surgical plans for hip and knee replacements using software that provides 3D models and other tools. Virtual screens displayed by mixed reality devices can provide information related to surgical progress, a patient's vitals, and more.

Scientific advances are unlocking a wide range of alternatives to IVF

From refined artificial insemination and microsurgical sperm extraction to experimental uterine transplants, scientific innovation is rapidly advancing potential fertilization technologies. But they come along with costly trials, some ethical dilemmas, regulatory issues, and more.

Thousands of donated human kidneys are thrown away annually

Ten donated kidneys are thrown away daily even though thousands of people are awaiting a kidney transplant. Listen to a kidney doctor and a 2012 economics Nobel laureate discuss why this happens and how the organ transplantation system may be improved. Transplant centers are penalized for low transplant survival rates, they note, and that contributes to why hospitals may decide certain organs are just too risky to use.

The first CRISPR-approved treatment was for sickle cell anemia in 2023

Victoria Gray was the first patient to receive a CRISPR-based therapy, which eliminated her symptoms and restored her health. The therapy's initial cost of $2.2M has kept it out of reach of many patients.

‘Hope for Healing’: The first-ever use of an in utero stem cell treatment

In 2023, researchers at UC Davis performed the first-ever fetal stem cell transplant, attempting to cure a case of spinal bifida prior to childbirth using stem cells derived from the placenta. The trial, and others including an effort to treat muscular dystrophy, highlight the potential power of stem cell therapy.

The first child born via mitochondrial replacement therapy was born in 2016

The healthy baby boy's mother carried genes for a rare mitochondrial disease called Leigh syndrome and after multiple miscarriages the family opted to try the controversial procedure. It was conducted by a US doctor in Mexico. The procedure is prohibited in the United States.

Only 34% of Americans supported the Apollo program in 1967

After a fire killed three astronauts on the launchpad of Apollo 1, the public became ambivalent about funding the multibillion-dollar program until the successful moon landing in 1969. The landers alone cost $388M, while each spacesuit cost $100,000.

New eye implant clinical trial recruiting in 2026

University of Southern California researchers have launched a phase 2b clinical trial of a stem cell implant designed to restore vision in people with advanced dry macular degeneration. Patients will be randomized to receive the stem cell implant or a simulated procedure and placebo implant. This type of larger, second-stage clinical trial is designed to confirm efficacy and dosing and to look for side effects. It's one of the stages that precedes the US Food & Drug Administration approval of a device.

The lifetime cost of the American dream exceeds $5M

A new analysis suggests it costs millions of dollars to maintain the American dream over a lifetime. The price tag includes retirement, healthcare, higher education, homeownership, and other core elements of a comfortable life for the average American.

Why crash test dummies cost a million dollars

Crash test dummies are crucial in the fight to protect car passengers from potentially catastrophic crashes. So how are they made? And why are they so expensive? This 8-minute video breaks down the high-tech products—which can cost over $1 million...

What's next for surgical robots?

Since robots were introduced into the operating room in 2001, their patients have seen improved recovery times and decreased risks of infection. This article describes what's next for surgical robots, which, so far, have remained under human...

The man who turned his leg into a hotspot

Biohacker Michael Laufer recently had a 512GB drive implanted in his leg, which can store data, stream music or movies, and power a hot spot and mesh network. It's called the PegLeg, and WIRED's Daniel Oberhaus spoke with Laufer about the device and the field of biohacking.

How much your blood really costs

In the US, donating plasma twice a week can earn you $400 a month. But this system only works by targeting people who need the money most. Plasma clinics are placed in low-income zip codes, and frequent donation may increase health risks.

In 2024, the average US wedding cost was around $33K

That's up from $29K in 2023, according to this 2024 weddings report. But that’s not the only surprising fact from the report: For instance, 89% of couples started wedding planning before getting engaged.

Concierge services are one of the top medical costs retirees fail to factor into their planning

One of the unexpected medical costs retirees are facing is thousands of dollars a year for concierge care membership fees. A typical annual fee can average $3,500. Concierge care is an option that's particularly popular among older adults with more complex health needs and in some areas of the country doctors are increasingly turning away Medicare patients and only accepting new patients willing to pay annual fees for concierge medicine. (Some users may experience a paywall.)

US child care costs, mapped

It's no secret that child care in the US is expensive, but this map provides more color to that observation by showing the average annual price of child care in licensed child care centers for infants, by state, in 2023. South Dakota, for instance, had the lowest infant child care cost at $7,862 per year. See how the rest of the states fared here.

The cost of covering family health insurance has tripled in 20 years

The Milliman Medical Index tracks the real cost of health insurance for people covered through employer-sponsored plans. In 2025, healthcare for a family of four cost an average of $35K, including employer contributions, out-of-pocket expenses, premiums, and offset wages.

Graduate/professional schools often cost more to attend than undergraduate schools

Grad and professional school cost more than undergraduate schools. Individuals with advanced degrees owe many times more than graduates with bachelor’s degrees. For example, the average student debt held by a PhD was around $125K in 2023, while those with undergraduate debt averaged $37K.

In 1984, a dying infant lived for three weeks with a baboon heart

Pediatric-sized hearts are very hard to find. They're about the size of a walnut. When a premature baby girl was born with a fatal heart defect in 1984 her care team transplanted a 7-month-old baboon's heart into the patient. The organ was not genetically modified but still the infant lived for several weeks. This roughly hour-long documentary from the medical institution, features the patient's mother, clinician, and more discussing the controversial procedure and aftermath.

Here's how much money Americans spend on Halloween

In 2024, Americans are expected to spend more than $11B on Halloween, which averages out to roughly $104 per person, according to the National Retail Federation's Halloween Spending Survey, conducted by Prosper Insights & Analytics. That $11B number includes an anticipated almost $4B spent on costumes. See the full breakdown here.

The average cost for an in-state, public university is close to $30K per year

To cover the cost, students turn to a variety of sources. Parental contributions plus savings funds cover about half of the expenses on average, with students relying on other sources—typically federal aid, in the form of scholarships and loans—to cover the rest.

The Cybathlon is an international competition for assistive technology

The competition pits teams against each other in eight races targeting different innovations, such as arm prostheses, leg prostheses, and vision assistance. Participants in the Cybathlon use it to push the boundaries of technology, including brain implants and assistive software that incorporates AI.

The lifetime costs of caring for a dog can run anywhere from $16,440 to $52,075

The cost depends on the dog's breed, size, and ongoing health conditions, according to a recent Rover survey. Tactics such as purchasing dog food in bulk and asking for a generic version of your dog's prescription medications can help reduce costs.

Your feet can expand—permanently—due to pregnancy

A hormone called relaxin loosens tissues in the body to allow them to expand during pregnancy, affecting muscles and body parts—including the feet. The structural changes that occur in the foot as it expands are sometimes permanent. This article states that researchers have found as many as 61% of new moms did not have their foot sizes return to their prepregnant state. (Some users may encounter a paywall.)