Hear Aristotle Domingo, a bilateral amputee athlete, discuss his amputation journey.

Listen to how bionic limbs are reshaping what it means to live as an amputee in this award-winning 2022 podcast series covering the stories of two amputees who struggled with shortcomings in prosthetic technology.

Listen to an amputee describe what it was like in the aftermath of his partial foot amputation and how his chronic, extreme pain fueled his depression and his decision to attempt to alleviate the pain with the radical surgery.

Hear about life as an amputee and how mirror box therapy helped.

Palliative care physician BJ Miller describes his phantom limb pain and itching after losing both legs and half an arm in an accident. Mirror box therapy eventually helped him, alongside physical therapy. This podcast also features neuroscientist V.S. Ramachandran who explains how he developed mirror box therapy in the 1990s.

See what analysis of one man's amputated leg, donated to The Bone Museum, tells us about his otherwise invisible pain.

A first-person account of receiving an Alzheimer's diagnosis

Having Alzheimer's is a bit like having a part of your brain sliced away each day, according to author Greg O'Brien. This 34-minute podcast episode introduces O'Brien and his co-host, author David Shenk, as the two embark on a multi-season conversation on Alzheimer's disease and O'Brien's diagnosis.

Tony Hawk’s rise from outsider to skateboarding legend

In this podcast, Tony Hawk discusses his path from being an outsider in a niche sport to becoming skateboarding’s most recognizable figure—reflecting on competition dominance, business ventures, and lessons learned throughout his career.

Amputees must navigate the challenging medical and economic aspects of limb support and replacement, but advances in technology and research may reduce these costs.

Black patients are losing their limbs at a rate triple that of other groups due in large part to inequities in diabetes care and management.

Lee Spencer, a single-leg amputee, broke the world record when he rowed solo and unsupported across the Atlantic Ocean in 2019.

Every 3.5 minutes in the US, a limb is amputated due to diabetes.

Readers thought the fictional Civil War vet George Dedlow, a character suffering from phantom limb pain in an 1866 story in The Atlantic, was real—and sent donations and stopped by the hospital to meet him.

Social support plays a critical role in recovery from addiction

This engaging TEDx talk from addiction researcher Jacki Hillios explores addiction recovery through a transformative lens and Phoenix Multisport—an innovative program helping people rebuild their lives through active lifestyles. By living out its core message that people are not defined by their disease, the program demonstrates the power of social support in recovery.

The life of Anthropic's CEO, and how losing his father inspired his vision for AI

In 2006, Riccardo Amodei passed away from a rare illness, four years before a breakthrough treatment made it 95% curable. Seeking to accelerate scientific progress to prevent similar losses, Dario Amodei shifted his graduate studies at Princeton from theoretical physics to biology and has since pursued technological solutions to address complex biological problems.

Watch this video letter (via Facebook) from a kidney recipient to his donor

A kidney recipient named Justin reads a letter he wrote to his deceased donor about how the person's generous kidney donation saved his parents from having to watch him suffer and his brother from having the pressure of perhaps being his only shot at a life-saving transplant.

Watch this behind-the-scenes interview about the first person ever diagnosed with autism

Two reporters from The Atlantic tell the story behind their effort to track down the first diagnosed autism patient, Donald Gray Triplett, in Forest, Mississippi, and how his life turned out decades later.

Interface device implanted into ALS patients restored some of their abilities

Most people with amyotrophic lateral sclerosis, or Lou Gehrig's disease, require assistance with daily life due to loss of motor control. The electrode-coated, stent-like device used motor mapping data and machine learning to translate brain activity into actions.

An essay exploring how living day-to-day with a brain implant helps restore a sense of identity

Companies like Neuralink are experimenting with volunteers who have lost control over their bodies. Many of the program's participants claim the most significant benefit from the tool is the ability to perform simple, mundane tasks, such as playing video games or shaking hands, rather than more obvious milestones like walking or eating. This essay explores what it's like, day to day, to use a brain implant.

Non-amputees can be tricked into thinking they have phantom limbs with rubber arm experiments.

Using AI to restore speech 30 years after a stroke

Through a novel surgical procedure involving electrodes implanted in the brain, along with the help of artificial intelligence, a stroke patient is regaining her ability to speak. This technology converts her thoughts into speech through a digital avatar, allowing her to verbally express herself for the first time in decades.

An avowed rationalist discusses his near-death experience

Documentarian Sebastian Junger, a veteran reporter and skeptic discusses his experiences—in particular, a frightening vision—after an aneurysm and internal hemorrhaging left him nearly dead. Junger talks about his NDE, the possible scientific explanations, and how that day changed his fundamental worldview.

Watch patient stories describing life with macular degeneration

This video series features patients discussing their experiences with the disorder, family members describing caregiving, and other insights about the disease.

The journalist who let AI speak with his voice

Journalist Evan Ratliff became the object of his own story: He opted to clone his voice, feed it into an AI chatbot, and have it do the talking. What could seem like a fun experiment ended up revealing just how far the capacity of artificial intelligence can go in imitating our identities. Hear the ins and outs of how Ratliff achieved this in this fun and thought-provoking episode.

An experimental bionic knee has been directly integrated into the user's muscle and bone—not an external socket—marking a significant prosthetic advancement.

Learn more about Niagara’s death-defying daredevils

This podcast from the Niagara Falls Daredevil Museum explores 19th‑ and early 20th‑century Niagara daredevils—like tightrope walker Charles Blondin, barrel-stunter Annie Edson Taylor, and Sam Patch—detailing their feats, dangers, and public spectacle.