In the late 1800s, over 10,000 entries of the Oxford English Dictionary were written by a patient in a psychiatric hospital.

Charles Dickens legally separated from his wife, then tried to have her committed to a mental asylum.

The peer support movement may date back to 18th century France

At the Bicêtre Hospital, an asylum near Paris, Jean-Baptiste Pussin (who had previously been a patient but later led the hospital administration) tried to hire as many staff as possible from among recovered patients. Chief physician Philippe Pinel found these individuals to be kinder than other staff and "averse from active cruelty" which was common at the time. This approach allowed the facility to move away from shackling patients and other violent methods.

The virus was officially described for the first time in 1789

Michael Underwood, an English physician and surgeon, was the first to describe the disorder, noting it caused disability in the lower extremities in children. Large-scale outbreaks of the disease were not observed until the late 19th century.

The term schizophrenia was coined by Swiss psychiatrist Eugen Bleuler in 1908

He launched the word during a lecture at the German Psychiatric Association in Berlin. In his talk he focused on the splitting of psychic functioning as a defining feature of the disease and noted it wasn't associated with dementia or factors like early puberty onset.

Read the original 1907 paper on the first known Alzheimer's patient

Alzheimer's disease was first identified by Dr. Alois Alzheimer in 1901, following a postmortem brain examination of a patient experiencing memory loss and other symptoms. Alzheimer's original paper was largely lost until 1995, when an English translation was published in a medical journal.

Hippocratic doctors treated severe mental illness with the poisonous plant hellebore

Since symptoms like hallucinations were believed be due to an imbalance of black bile, yellow bile, blood, and phlegm, the treatment at the time was to bring those humors back into balance. That meant standard treatments could include bleeding a patient or using substances like hellebore to induce vomiting or diarrhea.

'Mental hygiene' was the 1843 term for mental health

It was coined by American psychiatrist William Sweetzer to reference the same idea as personal hygiene. Mental hygiene, in Sweetzer's view, needed to be maintained in the same way people attend to their personal cleanliness, an idea that was supplanted by better understanding of the complexities of mental health disorder causes in the decades that followed.

Browse a fan-made 'Newspeak Dictionary'

In Orwell's "1984," citizens of Oceania are expected to use Newspeak, a form of English that limits abstract thought and reinforces the government's version of reality. This satirical dictionary of the language demonstrates how Orwell constructed a lexicon for his fictional world.

Oxford scientists turned Fleming’s mold discovery into medicine

In 1939, a team at Oxford—including Howard Florey, Ernst Chain, and Norman Heatley—revived Fleming’s forgotten discovery. Using makeshift equipment like bedpans and milk churns, they purified enough penicillin to prove it could treat deadly infections.

How a sick George Orwell finished '1984'

The writer worked on the novel while living in a remote cottage in Scotland. While he was there, he was in a boating accident that sent him overboard, eventually leading to a fatal bout of tuberculosis. Orwell finished the novel (and massive revisions) while trying to recover. He died in 1950, at 46.

Why one Emily Dickinson biographer believed she had epilepsy

Lyndall Gordon's "Lives Like Loaded Guns" points to a "handicap" referenced in several Dickinson poems. According to Gordon, the condition was so stigmatized during Dickinson's life that it made her reclusive. In this NPR interview, Gordon explains why she believes the theory is the best explanation for Dickinson's notorious isolation.

Scientists identify hundreds of genes responsible for OCD

Researchers analyzed the DNA of more than 53,000 people with OCD and identified 30 areas in the genome linked to the disease, containing 249 genes of interest. Of those, several were linked to other brain disorders, paving the way for genetic treatments of various mental illnesses.

Deinstitutionalization in the 20th century unintentionally led to the incarceration of schizophrenia patients

Activism to shut down problematic asylums in the mid-20th century led to the community release of many patients with severe mental illnesses, including schizophrenia, but without adequate support, this deinstitutionalization in the 1960s and 1970s led to a significant increase in patients with schizophrenia ending up in prisons and homeless shelters.

More than a third of America's incarcerated population has a mental illness

Fueled in part by America's deinstitutionalization movement and gaps in mental health support, an estimated 44% of those in jail and 37% of those in prison have a mental illness, according to figures from 2012, the latest available. Population-wide, only 18% of the general population is estimated to have a mental illness.

Scholars believe Dickens wrote over a million words of nonfiction

The author began writing professionally in his teens, first as a court reporter, then for many papers, penning op-eds, criticism, and other miscellany. While Dickens is often discussed as a novelist, he has a massive corpus of works situated in reality.

Having five of nine key symptoms constitutes a major depression

Before professional standards were adopted, practitioners used varying criteria to diagnose mental health disorders. By the 1970s, more objective lists were organized, culminating in this list of polythetic criteria—a list of symptoms where no single criterion is required, but a minimum number must be present.

When Dickens was 12, his father was imprisoned for debt

John Dickens was imprisoned at Marshalsea Debtors' Prison in London for failing to pay his debts. The experience forced the young Charles to leave school to help provide for his family. It also eventually informed his fiction, which often called for social reform, including the abolition of debtors' prisons.

Browse an Orwell superfan's book collection

This Brown University Library exhibit displays scans from collector Daniel Leab's extensive trove of Orwell's works, including many first editions and translations. In addition to the beautiful covers, there's also plenty of fascinating bibliographic information.

The first identification of Alzheimer's was made in 1906

The first case of Alzheimer's disease dates to the early 20th century when Dr. Alois Alzheimer had 51-year-old Auguste Deter as a patient. Deter struggled with sudden memory issues and aggressive, irrational behavior. After Deter's death, Alzheimer examined her brain and found strange collections of molecular pileups.

Six of history's most unethical human experiments, from deliberate flu exposure to withholding syphilis treatment

Some of the progress made in mental health treatment, vaccines, blood transfusions, and more came about before the advent of consent and ethics committees, resulting in serious physical and psychological harm that participants in studies were not even anticipating.

Listen to how gaps in schizophrenia care helped to lead to a murder

Michael Laudor attended Yale, succumbed to schizophrenia, and killed his pregnant fiancée. The podcast, which includes a long but moving interview with Laudor's friend Jonathan Rosen, uses the tragedy to frame how America's approach to severe mental illness has fallen short.

Winston Churchill said he was comforted by 'Pride and Prejudice' during World War II

The prime minister was bedridden in a hospital with pneumonia in 1943. In his memoirs, Churchill recalls how Austen's "Pride and Prejudice" comforted him, especially because its characters remained calm amid the political turbulence of the time.

Improve your typing speed by retyping classic literature

Why practice with nonsense letters and syllables when you can retype full books you always wanted to read, from Jane Austen and Sir Arthur Conan Doyle to George Orwell and W.E.B. duBois. And it's free.

The oldest medical report of a near-death experience dates to around 1740

In 2014, Dr. Philippe Charlier, a medical doctor and archeologist, found a French medical book from 1740 that described the near-death experience of a pharmacist. Using the Greyson Scale, Charlier found that the incident would have rated at least 12/32, more than high enough to scientifically classify as an NDE by today’s standards.

Historians theorize Vincent Van Gogh suffered from Ménière's disease or epilepsy

A century after researchers suggested he suffered from epilepsy, some researchers in the 1990s began to support an alternate diagnosis: Ménière's disease, since he had suffered from severe, repeated attacks of disabling vertigo. Still, some researchers remain skeptical of the Ménière's diagnosis. One posits that Van Gogh had temporal epilepsy complicated by his absinthe consumption.

Play 17th-century death roulette

Before modern science and medicine, death was much harder to escape. Using real mortality records from London's Dreadful Visitation–a collection of all the Bills of Mortality from 1665–this interactive game gives you an idea of what may have possibly killed you during the Great Plague. Grow your appreciation for life today as you stumble upon causes of death like “livergrown” and “drowned at St. Katharine’s by the Tower”.

Mental illness in the US costs roughly $282B annually nationwide

That figure, estimated as part of a 2024 Yale analysis that aimed to better understand the macroeconomic implications of mental illness, included the costs of mental health treatment, income loss, and overarching economic setbacks associated with mental illness.

Orwell warned readers about how abuse of language can lead to dystopias

In his 1946 essay "Politics and the English Language," Orwell argues that language is the primary tool of political control and is "designed to make lies sound truthful and murder respectable, and to give an appearance of solidity to pure wind." The essay warns readers that how they use and consume language will dictate what they permit—or prohibit—in society.

Why might someone want to stay in psychosis?

Author Abigail Gosselin writes that her verbal auditory hallucination, often assumed by others to be harmful or threatening in nature, offered a salve to loneliness, even as it told her to kill herself. This perceived benefit and others Gosselin shares offer insight into why people in psychosis may struggle to adhere to treatment and medication plans.

Analysis finds dementia was rare in ancient Greece

Ancient medical texts seldom mention severe cognitive decline, suggesting that such conditions were uncommon. This scarcity is attributed to factors like shorter lifespans and active lifestyles, implying that modern environmental and lifestyle changes—along with longer life expectancy—contribute to the current prevalence of dementia.

Obsessive compulsive disorder is a mental health disorder, not a personality quirk

In popular culture OCD has been incorrectly overused to describe neatness or perfectionistic behaviors, but the disorder involves intrusive thoughts and compulsive behaviors that take over a person's actions.

'Melancholia' was the ancient Greek term for depression

"Melancholia" in Hippocrates's time was derived from the Greek word for black bile. This term made sense in its context since the Greeks believed that depression stemmed from an improper balance of the four humors.

Learn how Hollywood tries to get mental health portrayals right

"Entertainment is always the first priority," the director of medical research for "Grey's Anatomy" and "Private Practice" explained in this Newsweek article. But, medical consultants and dedicated groups like the University of Southern California's Hollywood, Health, and Society program, can help inform shows' characters, actions, and sensitivities on subjects like mental illness.

See the list of alleged communists Orwell gave to the British government

In 1949, Orwell provided a list of communist sympathizers to a British anti-communist propaganda unit, naming figures like actor Charlie Chaplin and writer John Steinbeck. When it was made public in 2003, some called Orwell a government informant, though others blamed his tuberculosis, which would take his life a year later, while others blamed his romantic interest in the woman who asked him for the names.

Why Emily Dickinson's poems were heavily edited after her death

Mabel Loomis Todd worked alongside Dickinson's confidant, Thomas Wentworth Higginson, to publish the first volumes of Dickinson's poems in 1890 and 1891. They removed many of the poem's idiosyncrasies, including their dashes, and created titles where Dickinson had provided none.

The bloody history of the true crime genre

The true crime genre appears to have crawled out of an unlocked closet between 1550 and 1700. Rising literacy rates and printing technologies during this period led to leaflets and ballads-turned-broadsides that graphically regurgitated the findings. These products often included woodcuts of the crime's "unsavory acts.". Such content was snapped up by the "artisan class and above" as poorer classes lacked the funds to fuel the hobby.

Maryland required cholera researchers to fly a yellow warning flag—signifying quarantine dangers in the 1970s

University of Maryland Hospital researchers intentionally infected volunteers with the cholera bacterium in the late 1970s to further their understanding of the disease. They proceeded with this work following the recommendation of a US government panel. (Some users may encounter a paywall.)

See how antidepressants were discovered

The decadeslong journey to the three major types of antidepressants began with medications designed to treat other maladies. Watch to learn more about how attempts to treat tuberculosis and blood pressure disorders led to new insights about neural chemistry and mood.

Browse Emily Dickinson's original handwritten poems

Harvard's Emily Dickinson Archive offers free access to the poet's papers from over a dozen libraries, allowing you to see the original drafts of some of her most famous works, sometimes scribbled on envelopes and scraps of paper. (And, even better, you can search the database by typing in your favorite lines!)

Nobel Prize winner William Butler Yeats was fascinated by magic and the occult

The Irish poet and 1923 winner of the Nobel Prize for Literature laid out his beliefs in a 1901 essay, entitled "Magic," and was a member of several organizations dedicated to occult and mystical practices.

Some dementia cases may be linked to microorganisms in the brain

Researchers now know that, much like the gut, the brain is home to an ecosystem of microorganisms—the brain microbiome. While this area of study is still new, some scientists believe 50% of bacteria-caused dementia cases could be treated. (Some users may encounter a paywall.)

The 'Penicillin Girls' made mass production possible

In Oxford during the early 1940s, six female technicians—later dubbed the “Penicillin Girls”—worked long hours tending mold cultures and extracting tiny amounts of penicillin.

George Orwell, avid outdoorsman

The writer is often pigeonholed as either a cranky paranoiac or a self-righteous scold, but this essay by Danny Heitman explores a lesser-known side of Orwell's personality: his love for nature, something that's subtly expressed in some of his greatest works.

The pharmaceutical industry evolved, in part, from the discovery of synthetic dyes

In 1856, a chemist accidentally discovered mauveine, the world’s first synthetic dye, while trying to make quinine to treat malaria. The synthetic dyes that followed helped reveal germs under microscopes, paving the way for modern imaging techniques and breakthrough treatments, such as antibiotics.

Hear 2 literature professors unpack the legacy of 'Animal Farm'

The University of Oxford's David Dwan—a professor of English literature and intellectual history—is an Orwell scholar who has written about the author's politics, especially as they relate to "Animal Farm." In this conversation with Dr. Nathan Waddell, from the University of Birmingham, UK, Dwan explores how framing the novella as a beast fable both made it more accessible and allowed it to be overly simplified.

Human records of influenza stretch back more than two millennia

Accounts of flu-like illness appear as early as 412 BCE, when Hippocrates described a sudden wave of cough and fever. Centuries of recurring outbreaks culminated in the first clearly documented pandemic in 1580, spreading from Asia into Europe and Africa.

Human records of influenza stretch back more than two millennia

Accounts of flu-like illness appear as early as 412 BCE, when Hippocrates described a sudden wave of cough and fever. Centuries of recurring outbreaks culminated in the first clearly documented pandemic in 1580, spreading from Asia into Europe and Africa.

A teenage Dickens found work as a political journalist

Dickens found work as a reporter for the Mirror of Parliament, a weekly newspaper focused on the British legislature. After a few years, he moved to the Morning Chronicle, where he began producing his creative work. Professor John Drew, author of "Dickens, the Journalist," said that the writer "realized he could wield a much more direct, if not more glamorous kind of power, by using his position as a leading writer of fiction and a magazine editor."

Read the works of Charles Dickens

Dickens' work has long been in the public domain, meaning it's freely available to readers. Project Gutenberg's collection of Dickens' novels allows you to read classic novels like "Oliver Twist" and "A Tale of Two Cities," as well as early works like "Sketches by Boz," at no cost.

Some say baseball's drug problem goes back to the late 1800s

At age 32, pitcher James “Pud” Galvin was feeling tired and decided to take "the Brown-Séquard elixir," which contained a testicular fluid from dogs and guinea pigs, believed to invigorate tired bodies. It might've worked: Galvin pitched a two-hit shutout the next day.