Alcohol may be responsible for about 5% of cancer cases and 4% of cancer deaths in the US.

About 40% of cancer cases are linked to preventable risk factors

Maintaining a healthy weight, engaging in regular physical activity, and consuming a balanced diet can lower cancer risk. Research indicates that about 40% of US cancer cases are linked to preventable factors, including poor diet and inactivity. Understanding these mechanisms empowers individuals to adopt healthier lifestyles for cancer prevention.

Breast, prostate, and lung cancer are the most common forms of cancer.

Roughly 1 in 5 cancers are caused by viruses

About 20% of cancers are caused by viruses, with seven specific oncoviruses causing between 10% and 15% of cancers worldwide. These include human papillomavirus and hepatitis B and C viruses, which can lead to diseases such as cervical and liver cancer. Understanding the mechanisms of these viruses is crucial for prevention and treatment strategies.

Explore more statistics about cancer

The American Cancer Society's Cancer Statistics Center estimates there will be more than 2 million new cancer cases and almost 620,000 cancer deaths in the US during the course of 2025. Breast, prostate, and lung cancers remain the most prevalent. This interactive tool provides detailed statistics on cancer incidence, mortality, and survival rates, allowing users to explore data by state, cancer type, demographics, and risk factors.

US cancer mortality rates have been falling for 25 years

The American Cancer Society's "Cancer Facts & Figures 2025" report provides comprehensive statistics on cancer incidence, mortality, and survival rates in the United States. Cancer rates in the US continued a long-running downward trend, driven primarily by a steep drop in lung cancers (mostly from a decrease in habitual smoking) and better preventative monitoring. This site leads to incredibly in-depth reports and slides on the current state of the fight against cancer.

Alcohol use disorder is the most common addiction in the US

This comprehensive overview from the Addiction Center uses recent data from SAMHSA’s National Survey to examine the 10 most common substance dependencies in the United States. It ranks addictions from alcohol (affecting 28.3 million Americans) to barbiturates, while highlighting key trends, risks, and societal impacts.

Explore why Americans are drinking less alcohol

US alcohol consumption fell 5% in 2025, with beer and wine leading the decline. Economists point to tighter budgets and less face-to-face socializing overall, while younger Americans are increasingly choosing not to drink.

America's top causes of death are heart disease, cancer, accidents, and stroke

Heart disease killed more than 680,000 people in 2023 and cancer killed around 613,000 people that year. Both causes of death are far above the next leading cause of death—accidents, which numbered around 223,000. Provisional data for 2024 indicates the leading causes of death remained the same.

The seven viruses that cause human cancers

Certain viruses have been linked to the development of human cancers. These viruses account for up to 20% of cancers worldwide, causing cancer by interacting with host proteins, proliferating within weak immune systems, and commandeering susceptible human cells. Unlike other viruses, human tumor viruses don't kill host cells, allowing them to establish persistent infections. The seven viruses include the Epstein-Barr Virus, the Human Papillomaviruses, and more.

'1440 Explores,' Episode 2: Why We Drink and What It Does to US

Alcohol is the world's most popular drug—a molecule that can calm or excite and bond communities or tear them apart. We trace alcohol's journey from ancient rituals to modern hangovers, uncover how it shaped civilizations, and dive into the neuroscience of how it affects your brain and body. With insights from leading experts, we ask: Given all that we know, why do humans continue to drink?

The WHO labeled aspartame as 'possibly carcinogenic' but US regulators consider it safe

The International Agency for Research on Cancer, an arm of the World Health Organization, labeled aspartame—the artificial sweetener in Diet Coke—as one of several hundred possible cancer-causing substances in 2023. The determination was based on animal and human studies and "limited" evidence linking it to liver cancer. The WHO and US Food and Drug Administration both say the substance is safe at moderate levels. The FDA says a person weighing about 132 pounds would need to have 75 packets daily to reach an unsafe level.

Total per capita US consumption of beer has dropped 30% since the 1980s

Between 2011 and 2021, AB InBev and MolsonCoors (two of the leading beer parent companies in the US) experienced a combined 17% drop in US market share. Budweiser parent company AB InBev has focused on premiumization and diversifying their product offerings in recent years to combat the losses.

The long history of alcohol and sports

Spectators have long enjoyed alcohol at sporting events, dating back at least to ancient Rome. This article unpacks how companies leveraged this history to make beer a central part of sporting events and masculine culture.

Explore this interactive tool from the National Cancer Institute to calculate your risk of dying from various causes, including cancer.

Alcoholics Anonymous leads to increased abstinence compared with other treatments

That's according to a 2020 meta-review of 27 studies. This large analysis found that Alcoholics Anonymous had between 22 and 37 percent abstinence numbers as compared to other treatments that had figures of about 15 to 25 percent. AA was founded in 1935, in Ohio, and depends on peer connections and consistent meeting availability. (Some users may experience a paywall.)

Exposure to ionizing radiation from nuclear accidents can damage DNA

The damage can increase the risks of cancer, cataracts, heart disease, and other illnesses based on exposure times and intensities. Contaminated food, water, air, or soil from near nuclear accidents can further prolong one's exposure.

Learn how colorectal cancer is linked to the American diet and chronic inflammation

A University of South Carolina colon cancer researcher offers insights from his own research and notes that more exercise, social support, and eating fruits, vegetables, legumes, and foods like fish and olive oil—often called the Mediterranean diet—are associated with better health—and could improve our colons.

Coffee is, generally, good for your health

While overconsumption certainly has its drawbacks—hello, not sleeping until the sun rises—on the whole, coffee is fine, even beneficial, for your health. It can even help prevent serious health conditions, like heart attacks and liver cancer.

The federal government allowed toxic chemicals into alcohol during Prohibition

Industrial alcohol was still legal during Prohibition, and was often used by bootleggers. In an attempt to disrupt the black market, the government required toxic additives to be included in industrial alcohol, leading to more than one death.

Gen Z is drinking less alcohol than older generations

In the years 2001 through 2003, 72% of adults under age 35 said they drank. But by the time the years 2021 through 2023 rolled around, only 62% of under-35 adults could say the same, according to one recent study.

How alcohol rewires your brain

Alcohol doesn't just make you tipsy—it rewires your brain chemistry in real time. It slows your brain with GABA, spikes dopamine to make you feel unstoppable, and blocks glutamate so you can't form memories. That mix explains everything from slurred speech to blackouts … and brutal hangovers.

The negative effects of cannabis use

After decades of criminalization, cannabis is a legalized drug in an increasing number of countries around the world. This allows for accurate, robust research on the drug's effects on humans . While weed isn't as harmful as alcohol, regular usage has its negative effects. As strains of the drug become stronger, so does its consequences. Watch this video for a lucid look at the effects of cannabis on its users.

Cancer is a group of diseases characterized by the uncontrolled growth of abnormal, mutated cells that can spread throughout the body.

The numbers on US wine consumption

Ever wonder how much wine the average American drank in 1949? Wonder no more! The answer is 0.89 gallons. That’s way less than 2022, where the number has quadrupled to 2.86 gallons. Check out this simple table that tracks average United States wine consumption from 1934 through 2022, by individuals and as a whole. American wine consumption peaked during the early pandemic but has lessened since then.

Cigarette smoke exposure boosts MS risk by up to 55%, though smokeless tobacco doesn't

The components of the smoke itself are associated with these significantly increased risks, so it's something beyond nicotine itself that drives that risk. What's more, smoking also increases the risk of developing antibodies to MS-treating drugs.

Loneliness is more dangerous to your health than smoking.

The states in America that drink the most beer

Americans, in 2020, drank on average almost twenty-six gallons of beer per adult aged twenty-one or over, over the course of the pandemic.

Alcohol often accompanies memorial ceremonies around the world

“Pouring one out” for the dead is something that exists across the globe, in various cultures and forms. From the Irish wake to the Korean Sangnye, alcohol is frequently used as a way to honor the deceased and comfort the living.

American beer, by the numbers

This statistics-focused resource breaks down the shape of the beer industry in the US, outlining the amount of beer produced by American breweries, the state cranking out the most beer, and the states with the most breweries per capita.

Mycotoxins are toxic compounds produced by fungi—some show up in food

About a quarter of the world’s agricultural products are contaminated with mycotoxins. Some of these compounds can cause serious health problems, including cancer, so the US government has set up monitoring programs to detect them in our food and in animal feed. Humans can become ill if they eat contaminated food, but also if they ingest products from animals that had previously consumed these toxic compounds, such as milk from a cow that ate contaminated corn.

Sugar alcohols, a type of carbohydrate used as a sweetener, may elevate risk of heart attacks and strokes

Sold as erythritol, sorbitol, xylitol, and mannitol, these products—ones that aren't actually sugars or alcohol—are found naturally in certain fruits and vegetables. They are synthetically produced to be used at much higher levels as the sugar alternatives for sugar-free candies, cookies, and chewing gums. Erythritol and xylitol have been linked with elevated heart attack and stroke risks.

The non-alcoholic wine market

A no-nonsense, stats-based exploration of the relatively new market for nonalcoholic wine. Driven by people looking to consume less or no alcohol at all, production of nonalcoholic wine has increased dramatically over the last few years. This report details the basics of nonalcoholic winemaking, as well as the current state of the market and what to expect in the future.

Tattoo inks are largely unregulated by the FDA

With hundreds of ink manufacturers, all unregulated by the FDA, it’s hard to determine the exact ingredients in tattoo inks. Some pigments may contain carcinogenic chemicals, such as heavy metals and aromatic hydrocarbons, or even bacterial contaminants. Red ink often causes allergic reactions and may even contain lead or mercury.

The term 'alcohol' has Arabic origins

Linguistic research reveals a lot about the ancient origins of alcohol. For example, studying various languages reveals that "mead," an alcoholic beverage made from honey, came even before wine.

Symptoms of DNA loss may mimic those seen in mushroom poisoning or chemotherapy

Although no organism has ever lost all its DNA, the destroying angel mushroom contains amatoxin, which disrupts DNA transcription and is known to cause death via liver and kidney failure in three days. Doxorubicin, which tangles DNA to disrupt cellular replication, compromises a person's immune system.

How the federal income tax affected Prohibition

In the early 1900s, 30% to 40% of government tax revenue came from liquor, wine, and beer, a reliance that made Prohibition seem like a fiscal impossibility. But the passage of the federal income tax in 1913 changed the calculus, which helped allow the government to ban alcohol production and sales.

How Alzheimer’s disease becomes fatal

Despite more than 100,000 people with Alzheimer's dying each year, the specific cause of death is not the disease itself. Often, secondary diseases arise from complications with the disease, including pneumonia, severe falls, malnutrition, or infection. Read more about the range of complications caused by Alzheimer’s here.

Murder rates spiked in the US after COVID-19, and then declined in 2023

Criminologist and former investigator Jillian Peterson says whether a murder is solved in the US is nearly up to the flip of a coin, with the clearance rate for murder cases being about 50%. The US, which has more guns than citizens, has about roughly five gun homicides per 100,000 residents, resulting in the 28th-highest rate of deaths from gun violence compared to the rest of the world.

1 in 6 Americans get food poisoning each year

The US federal government estimates there are about 48 million cases of foodborne illness in the country annually, resulting in as many as 3,000 deaths and 128,000 hospitalizations. Food poisoning puts those with weakened immune systems, the elderly, pregnant people, and young children at particularly high risk. This chart of common disease-causing pathogens highlights common threats and details about them, including likely food sources.

Louisiana's 'Cancer Alley,' an area with hundreds of industrial plants and petrochemical production, has cancer rates 50% above the national average.

Fungal diseases cost the US around $19B annually

Estimates derived from health insurance claims, death certificates, and hospitalization data suggest that fungus is a significant medical issue. Each year, fungal diseases kill some 7,300 people—roughly the same number of deaths attributed to motor vehicles striking pedestrians. Around 130,000 people are hospitalized with fungal diseases, and the total national cost from fungal diseases is estimated to be about $19B—a figure that roughly matches Jamaica's entire gross domestic product.

Traumatic brain injury is a leading cause of brain death—and TBIs are trending up

Traumatic brain injury-related deaths have generally increased between 2000 and 2023, growing from roughly 49,000 to more than 68,000 in 2023. Firearm-related suicide is the most common cause of TBI-related deaths in the US, according to the Centers for Disease Control and Prevention. People also experience TBIs from falls, motor vehicle crashes, or assaults.

The best beer cities in the US

This list contains some expected mainstays, like Asheville, North Carolina, and Portland, Oregon, as well as less-mentioned enclaves, like Minneapolis and Richmond, Virginia.

More than 90% of America’s food allergies are triggered by 9 foods

Milk, egg, peanut, tree nuts, soy, wheat, fish, shellfish and most recently, sesame, are recognized as the most common food allergies in the US. Together, they are responsible for at least 90% of the serious food allergy responses in the country.

Lack of Vitamin D seems to be one major factor fueling MS risk

Researchers believe that a combination of factors can elevate MS risk, including a lack of vitamin D exposure in different locales, genetic history, cigarette smoke exposure, and Epstein-Barr virus infection.

More than 100 types of beer are produced around the world

Beer dates back to ancient times, and since then, the fermented drink has taken on many different styles around the globe, depending on the grain and ingredients used. See how pilsners, IPAs, Sours, and other types evolved from the drink's early history.

Tequila overtook whiskey as a top US spirits subcategory in 2023

Tequila sales in the US totaled $6.5B in 2023, surpassing whiskey's $5.3B. The shift was partially driven by premiumization, with the majority of supplier revenues coming from premium and super-premium tiers and brands.

Why the craft beer industry is in decline

The trend began in 2024, when more craft breweries closed than opened, and has continued since then. Some blame the rise of canned cocktails, hard seltzers, and non-alcoholic beers, while others point to declining drinking rates for Gen Z.

Twin studies suggest celiac disease is among the more genetically-linked disorders

Genetics appear to play a larger part in this condition's development than many other autoimmune disorders. Research shows a roughly 60-75% genetic probability that if one identical twin has it, the other will too. Celiac triggers a small intestine attack when people eat gluten, a protein commonly found in wheat, barley, and rye.

Horses can—and sometimes should—drink beer

Despite its reputation, beer is a good source of nutrition. In fact, it's a fairly common practice for horse owners to give beer to their horses. Beer is rich in skin-healing B vitamins, gut-stabilizing yeast, and hydration-encouraging barley. Plus, horse livers come prepared with special enzymes that break down alcohol, making inebriation nearly impossible.