This 1440 Original video dives into what the science says about phototherapy and its various potential applications.

Red light therapy—a treatment harnessing a specific form of energy that penetrates the top layers of skin—is marketed for skincare and wellness, but has its roots in NASA plant growth research.

High-powered red light therapy—delivered directly to nerve fibers via a fiber optic needle—has been used in recent experimental research to suppress pain.

Certain visible light therapies, when applied at specific intensities, can be used to treat skin conditions, including acne.

A 1974 Science News article proclaimed that within a decade, light therapy would be on par with traditional drugs.

See photos of ultraviolet light therapy, widely administered in the early 1900s, particularly among children with skin diseases, tuberculosis, rickets, and more.

NASA began investigating the healing properties of red light therapy in the 1980s, when researchers studying how LED lights could aid in photosynthesis noticed that their hands seemed to heal faster than normal under the lights.

Light therapy was widely used as a medical treatment for various maladies in the early 1900s before it was replaced by antibiotics.

The design of a psychiatric ward in Norway aims to integrate more circadian rhythm-friendly lights as part of its treatment protocols for conditions including psychosis, severe depression, and more.

Bright light therapy involves basking in 10,000 lux of light for 30 minutes each morning

Nothing is better than going outside and soaking up real sunlight. However, this is harder in winter, especially in very cold and cloudy regions. SAD lamps are designed to project 10,000 lux—a unit of illuminance, or how much light actually hits a surface (rather than how much is produced, like watts). This video discusses product options and practical considerations.

Jaundice, which can make the skin and eyes appear yellow, is a buildup of bilirubin, a waste product that forms when old red blood cells break down.

Photodynamic therapy is one current treatment for age-related macular degeneration.

Unlike America's recommendations, Australian authorities don't encourage routine sunscreen use for darker skin tones—reasoning that melanoma risk is low, and it's better to get UV exposure to help the body naturally produce vitamin D.

Read Norman Rosenthal’s original 1984 paper describing SAD

The study helped formalize research and diagnosis of seasonal affective disorder, catalyzing the development of therapies (like bright light) and leading to broader adoption of effective treatments. It also helped connect the influence of light and seasons on biological mechanisms in the human body, spurring exploration of circadian rhythms.

Laser skin treatments can promote the production of collagen

Skin resurfacing vaporizes the top layer of skin to reveal healthier, new skin, while collagen can give the skin structure and elasticity. Such procedures treat scars and burns, but may leave light spots on the skin.

Psychedelic side effects, including worsening mental health for some patients, give pause

This article explores whether the therapeutic potential of psychedelic drug use is really as good as current research suggests. Scientists are exploring its applications for conditions ranging from the existential crisis that can accompany terminal diagnoses to chronic mental health conditions, including anxiety and PTSD.

The origin of LASIK eye surgery, from a lab incident to federal funding and widespread use

After a University of Michigan engineering student suffered retinal burns from an ultrashort pulse laser, researchers realized it could be used to reshape the cornea and improve a person's vision with greater precision than a scalpel and earlier laser technologies. Agencies, including the National Science Foundation, the National Institutes of Health, and the Department of Energy, provided funding to develop and commercialize the procedure.

The commercial and therapeutic potential of psychedelics

A 2006 study into the potential therapeutic benefits of psychedelics sparked a renewed interest in the field of psychedelic research, a development that has cascaded into commercialized ventures and experiences. This article details how growing research into the psychological benefits of psychedelics is matched by the rise of anecdotal reports, book deals, businesses, and corporate claims seeking to capitalize on psychedelic potential.

Blacklights can illuminate certain biological materials, including blood, teeth, and fingernails, because they contain fluorophores—molecules that visibly glow immediately after exposure to higher-energy light.

The weakest form of light that is dangerous to humans is ultraviolet

Unlike radio waves, microwave, infrared, and visible light, UV light can produce chemical changes, such as curing adhesives and resins, causing substances to fluoresce, and destroying the genetic material of microorganisms. This makes UV light useful for sterilization, forensics, and quickly drying nail polish.

Infrared light is most often associated with thermal radiation and cooking food

Although extensively used in remote controls for electronics, where LED lights send signals wirelessly, infrared cameras allow for night vision and thermography—imaging of heat patterns in the body to non-invasively reveal blood flow for supplementary diagnostics. Infrared radiation also provides heat in toasters, saunas, and other technologies.

Laser technology powers communication, medical and manufacturing tools

Lasers are used when scanning groceries, printing documents or undergoing cosmetic procedures to enhance efficiency, precision and accuracy. Missile defense, targeting and optical communication systems have made using laser technology habitual in the military.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Biohacking to boost personal health has become a concept that encompasses everything from vitamin regimens and cryochambers to brain implants and red light therapy.

Radio waves are used in broadcasting, weather radar, telecommunications, and GPS

Its ability to bend around obstacles and reflect off the ionosphere—an electrified layer of Earth's upper atmosphere—allows this type of light to travel long distances without damaging living things due to its low energy. MRI scanners, WiFi, and Bluetooth technologies are also applications of this form of light.

Psychedelic therapy's ethical guidelines (or lack thereof)

With a checkered history of misconduct, how will psychedelic-assisted therapists be held accountable in the emerging legal field? This article explores the nascent field's need for ethical guidelines and clear protection of patient rights when therapeutic breakthroughs teeter "on the edge of consent."

Bioluminescent reaction enzymes are often used in biomedical research

Near-infrared luciferase systems allow researchers to image and analyze cellular activity in living animals because they penetrate tissue more deeply than visible light. This provides a means of studying gene expression and protein interactions without harming the animals.

Experience a century of America's healthcare advances with this medical visualization, tracing a sampling of healthcare innovations from head to toe.

One theory claims the retinae of SAD patients may fail to adjust to less light in winter

Most people’s eyes become more sensitive to light in the winter months, but some do not. This failure to adjust causes ripple effects on those individuals’ biological clocks. This Ted-ED video provides a clear, brief, narrative explanation of the condition in six minutes.

Peptide TB-500, promoted for regenerative healing, is not FDA approved

Watch a board-certified sports medicine therapist detail his thinking about this synthetic peptide; he says it's "promising but unproven." He notes that this product is designed to mimic the natural protein thymosin beta-4, found in human and animal tissues, which promotes wound healing. TB-500 is classified as a research peptide for recovery, meaning it's not approved for human use and has not yet undergone rigorous human trials on its safety and efficacy.

Explore the current landscape for patient consent with this 1440 Original video tied to Henrietta Lacks' legacy.

Deepfake videos impersonating real doctors are spreading false medical advice

More than 100 videos, found primarily on Instagram and TikTok in August 2025, promoted products related to beauty, wellness and weight loss. While TikTok removed 94% of content violating its policies on AI-generated content, these deepfakes were watched and shared before removal, undermining public trust in medicine.

'Barbie' drug melanotan II purportedly offers tanning without the sun—but it's very risky

The substance is not approved by the FDA and is illegal to sell in settings including the UK and Australia. Published case reports discuss serious side effects, including melanoma, a type of skin cancer.

Mental health applications of psychedelics

Scientists are investigating psilocybin, ketamine, LSD, and MDMA (also known as ecstasy) as potential treatments for mental health issues. These drugs enable an altered state of consciousness, which can have beneficial or harmful impacts depending on the nature of the experience. Research suggests these drugs can be effective in treating substance use disorders, mental health conditions, including depression and anxiety, and psychiatric disorders, including schizophrenia.

The potential of virtual reality in healthcare

Virtual reality (VR) is carving new frontiers in healthcare, from aiding in stroke recovery to training medical professionals. This article in Time Magazine highlights the innovative uses of VR in medical settings, including its potential and current limitations.

Celebrities are able to promote prescription drugs on social media without any required mention of potential side effects due to a legal loophole.

'Magic ink' is redefining the tattoo

One University of Colorado professor has developed an ink that can be "turned on" with exposure to UV light, and "turned off" with sunlight. While the ink could help those who want to hide their body art from family members or coworkers, there are potential uses for medical procedures.

The US FDA considered mitochondrial replacement therapy during 2014 hearings

An agency committee assessed if this approach could have undesirable ripple effects across multiple generations and whether a clinical trial involving this approach would be appropriate. As of 2026, the US has continued to prohibit this procedure though it is legal in other settings including the UK and Australia.

Starting with red, colorful objects will appear to lose their colors the deeper they are submerged because water scatters light, reducing the amount available to reflect off objects and be observed.

Vision experts generally don't recommend blue-light-blocking glasses because there's no scientific evidence that the light from computer screens damages eyes.

What is CAR T-cell therapy?

A four-minute video about CAR T-cell therapy to help answer patients' questions: What is CAR T-cell therapy? How does CAR T-cell therapy work?

Psychedelic drugs are having a scientific renaissance

After decades of repression, psychedelic research is making a resurgence. Hear from a host of experts in this 20-minute video on what that could mean for the future of mental health. The current science on psychedelics believes LSD can cause a particular brain network to quiet or deactivate.

Do wearables help those with chronic disease?

The integration of wearable technology in healthcare has promised significant benefits for chronic disease management, yet the actual impact remains underexplored. This systematic review published in the Journal of Medical Internet Research...

Stem cell therapies

Stem cells' special attributes interest researchers developing new therapeutic tools for a variety of health problems. Much of this research is done with support from the National Institutes of Health (NIH). This page offers a snapshot of research programs funded by the NIH and the health problems those programs focus on.

A snapshot of progress in cancer treatments

The American Association for Cancer Research's "Snapshot of a Year of Progress" offers an overview of significant advancements in cancer research and treatment over the past year. Take a quick look at the rapid pace of scientific discovery and the translation of research findings into clinical practice. In 2024 alone, health regulators approved 15 new anticancer therapies alone.

An overview of modern clinical research on LSD

Researchers have determined that LSD, taken in a medical setting, decreases anxiety related to "life-threatening disease," reduces brain reactivity to fearful faces, increases the meaning and emotional response derived from music, and more. No complications of LSD administration have been observed in medical settings, though acute adverse effects, including exhaustion, nausea, and difficulty concentrating.

Proteins with limited light sensitivity prevent humans from seeing all types of light

Specialized photoreceptor cells in the retina called cones each possess photopigments that activate when exposed to three ranges of visible light. Other forms of electromagnetic radiation outside the activation range do not generate signals for processing in the brain, thereby limiting average human vision to approximately 10 million colors.

The difference between standard cancer treatments and emerging immunotherapies

If you've ever wondered what the difference was between immunotherapy and chemotherapy, this short video takes you through the steps. Briefly, chemotherapy attacks cancer in tumor cells directly, while immunotherapy encourages your immune system to fight it. There's more to it than that, but this delightful two-and-a-half-minute video provides a good primer.

The FDA rejected MDMA-assisted therapy for PTSD in 2024, calling for more research

The decision was considered to be a major setback for moving psychedelics into the mainstream for mental health treatment. Pharmaceutical company Lykos, who had applied for the approval, had already attracted significant support from patients, politicians on both sides of the aisle, and leaders in the mental health field.

Rayleigh scattering of light gives the atmosphere its blue skies and red sunsets

Light is deflected from its original path by atmospheric particles, where bluer light is scattered more than other colors. When the sun is at its highest point in the sky, it travels through the thinnest part of the atmosphere, scattering some blue light across the sky. A greater atmospheric path length at sunset scatters more colors, leaving only red, yellow, and orange.

See this 201-level explanation about mitochondria and mitochondrial replacement therapy

This 2022 academic presentation from Stanford University's Dr. Gregory Enns offers a detailed overview about mitochondrial therapy approaches. Enns, a pediatric geneticist, explains how well-functioning mitochondria support the human body.