One biologist is leading the blue zone criticisms—both questioning the original recordkeeping for these purported longevity-prone locations and pointing to recent research showing declining numbers of healthy seniors in several official blue zone regions.

Blue zones are geographic locations, such as Sardinia, Italy, where there have appeared to be disproportionately high numbers of healthy centenarians, perhaps due to factors including genetics, diet, social connections, and more.

Blue zones are regions with unusually high numbers of centenarians

Factors thought to contribute to longevity in these regions include diet and social connections, but their legitimacy is often questioned due to a lack of rigorous scientific methodology and potential record inaccuracies.

Read the main paper criticizing the concept of blue zones, which argues recordkeeping errors, pension fraud, and natural disasters likely explain the high numbers of purported healthy centenarians in certain locations.

Most self-reported claims of exceptional longevity are exaggerated, but read how demographers verify age claims and why some of the original blue zone demographers say blue zone regions are real and worth studying.

Visit these 'blue zones,' where people live the longest

Blue zones, a term coined in 2004 by National Geographic Fellow Dan Buettner, are regions in the world where people live the longest and healthiest lives. Researchers have identified a few key aspects defining the culture of these areas—physical activity, diet, purpose-driven lives, and more. Explore the top five blue zones from across the world here.

Dan Buettner, the journalist who popularized the term blue zones, fires back at criticisms of blue zones in this 2026 letter to the editor published by STAT News.

In the original 2004 blue zones study, which sought to verify the ages of long-lived, healthy populations in Sardinia, Italy, researchers hypothesized that inbreeding in these isolated communities may have helped promote their longevity. (Paywall may apply.)

Watch the trailer for journalist Dan Buettner's popular Netflix documentary series 'Live to 100: Secrets of the Blue Zones' which focuses on longevity insights from populations around the world.

Blue zone cooking—a concept that journalist Dan Buettner developed from his reporting on centenarian populations—emphasizes cooking with simple, fresh ingredients and echoes themes of the well-known Mediterranean diet.

Fort Worth, Texas, is the largest US blue zone area—a designation not from demographers but from journalist Dan Buettner's organization, which means Blue Zones LLC partnered with the city to help residents live healthier.

The formula behind super agers—those possessing health and cognitive skills of people decades younger

A study of about 1,400 super agers did not identify any underlying genetic mechanism for longevity. While researchers instead emphasized that sustainable habits involving positive social connections, sleep, mood, diet, exercise, and personal fulfillment help reduce long-term risks, there is no one-size-fits-all formula for everyone.

Super-agers: seniors 80 and above with the memory ability of people in their 50s

Studies show the number one indicator of whether someone is a "super-ager" is not diet or genetics, but the extent of their social relationships. Moreover, scans reveal noticeable physical differences in certain parts of the brain in patients with extensive social networks.

Can humans delay or reverse old age?

We're not sure yet. Researchers at the University of California San Francisco are studying why some conditions and behaviors, such as low-oxygen environments and exercise, benefit the aging process, hoping to reveal potential health applications. Some of this research focuses on klotho, a naturally occurring age-regulating hormone named after the Greek Fate Clotho. Animal studies on klotho brain injections found subjects had improved memory recall and age-related degeneration resistance.

Multiple new research paths may lead to slowing (or even reversing) aging

Aging has always been inevitable, but fasting, epigenetic reprogramming, and parabiosis seem to help people stay young. By studying centenarians, memory, and even the humble roundworm, scientists are looking for the genetic basis to live not just a long life, but a healthy one.

The quest to find natural ways to extend lifespan

Tales of searching for the Fountain of Youth persist. Our modern-day version is marked by promises of pharmaceutical miracles and a proliferation of viral "biohacking" routines. One doctor’s quest to unlock the keys to longevity stimulated much of this renewed fervor, though his ideas are often taken out of context.

Perceived isolation ages you

Mounting evidence suggests that socialization is a vital component of maintaining good health. Research published in 2024 from Mayo Clinic researchers analyzed the social lives of more than 280,000 adults and concluded that individuals that weren't likely to participate in extracurricular social activities and get-togethers were more likely to have a biological age older than their actual age—meaning that you may be 60 but health indicators would suggest you're older.

Moving your body every day is key to longevity

In an era of biohacking, where millionaires subject themselves to draconian routines and tests to de-age themselves, one study suggests a super simple key predictor of mortality: more than any other trait, how much subjects moved determined how long they'd live. Movement mattered even more than age in predicting overall life longevity. Researchers suggest this means we should all simply get outside a bit more. Read more about the study here.

The Dog Aging Project uses information from over 50,000 dogs to explore longevity

The study gathers health, lifestyle, and genetic data to understand what helps dogs live longer, healthier lives. Findings could also provide human health insights due to our shared surroundings and biology.

Doctors shift focus from extending lifespan to lengthening health span

As scientific advances extend the average human lifespan, many are turning their attention toward extending "health span." Health span refers to the number of years one is active and disease-free. The ultimate goal is to extend one’s health span to match one’s lifespan.

Health span: The number of years one is active and disease-free

As scientific advances continue to extend the average human lifespan, many are now turning their attention toward extending "health span." The ultimate goal would be to extend one's health span to match one's lifespan, which would necessitate a shift in focus toward the pursuit of healthy aging. (Some users may experience a paywall.)

Analysis finds dementia was rare in ancient Greece

Ancient medical texts seldom mention severe cognitive decline, suggesting that such conditions were uncommon. This scarcity is attributed to factors like shorter lifespans and active lifestyles, implying that modern environmental and lifestyle changes—along with longer life expectancy—contribute to the current prevalence of dementia.

Helping support others in older age linked to longer life

Analysis of findings from a long-term study of older couples first interviewed in 1987 and then followed for the next five years found that individuals who lend support to friends, neighbors, and relatives live longer. Non-helpers were more than twice as likely to die as helpers during the five-year period. That's even after controlling for factors including age, gender, and physical and mental health.

Doctors use three key physical markers to determine biological aging

The length of the ends of chromosomes (known as "telomeres"), the gradual change in collections of DNA molecules called "methyl groups", and the secretion of inflammatory proteins are all used as indicators of biological age.

Environment and genetics explain why animals have widely different lifespans

Both environmental conditions and genetic factors shape how long various animals live. For some creatures, colder conditions allow for less energy use and slower aging. Larger animals have fewer predators. While humans don't live the longest, we are a rare species that successfully lengthened its average lifespan over time.

The disparity in life expectancy between wealthy and impoverished nations has notably narrowed

In 1950, people in Norway lived to age 72, on average, while those in Mali lived to just 26. By 2015, the countries with the worst conditions had made such significant progress that the global average life expectancy had surpassed the rate of any nation in 1950.

Chronological versus biological age

Science has come to understand different types of aging. What we call age is simply the number of years since birth, or chronological age. At the cellular level, biological aging happens at different rates for different people, and explains why some seem to age more quickly (or slowly).

Each part of the human body experiences aging differently

With global average life expectancy cresting at 73 years, understanding how the body ages is imperative to effective medical treatment and maintaining a desired quality of life. This 13-minute video dives into how the body and its organs age "from head to toe."

Read a study documenting how 'old people' smell increases with age

Analysis of body odors from individuals aged 26 to 75 confirmed that 2-nonenal, an unsaturated aldehyde with an unpleasant, greasy, and grassy odor, was detected only in subjects aged 40 and older.

Climate determinism wrongly linked human traits and societal progress to geography

Historically rooted in Greek philosophy, its ideas used the latitudes where people were located to justify racial hierarchies, casting tropical peoples as lazy or inferior. These biases still influence how media and research portray people in climatically disadvantaged regions. (Some readers may experience a paywall.)

Organic food might be greener, but it’s not better for you

Weighing in on the ongoing debate surrounding organic versus “regular” foods, health experts explain whether organic foods offer significant health benefits. Studies suggest that organic foods have little additional nutritional value compared to...

Health food broke into the mainstream by the 1980s

A 1984 New York Times story noted that Americans were eating less red meat than a decade prior, and that, in general, the country was “talking, thinking and worrying about what they eat to a degree unique in the nation's history.” The feature then details foods that were then considered bizarre: whole-grain muffins, hummus, and a variety of vegetarian dishes. (Some readers may experience a paywall.)

Human settlements may be older than previously thought

This narrative article follows an archaeological team as they sift through the remains of Nahal Ein Gev II, an ancient village near the Sea of Galilee in Israel. Abandoned about 12,000 years ago, the site has been investigated for years and...

Ten writers and thinkers on what growing older actually requires of us

The Marginalian's Maria Popova curates a collection arguing our culture has learned to dread aging while forgetting it is a privilege, and that the antidote is sustaining passions strong enough to keep us from turning inward. Voices include Simone de Beauvoir, Joan Didion, Pablo Casals, and Kahlil Gibran.

The Chernobyl exclusion zone has become a unique wildlife refuge

Within the area—roughly the size of Yosemite National Park—animals such as wolves, bears, and feral dogs descended from the pets left behind have gradually adapted to low-level radiation. Eastern tree frogs in the area have darker skin than usual, which may have helped protect them from ionizing radiation.

Brain training game creates long-lasting changes in the brain that may help protect against dementia

Findings published in 2026 that tracked more than 2,000 older adults, examining dementia onset and completion of cognitive speed training activities, provide some of the strongest evidence yet that cognitive training games can help protect against dementia. Participants who underwent speed training and received booster sessions had a 25% reduction in the risk of dementia diagnosis compared with the control group.

Questioning the results of life on K2-18b

An analysis of the atmosphere of an exoplanet called K2-18b identified the presence of biosignatures—molecules that are created by living things on Earth. This discovery may indicate life exists beyond Earth, but the lack of environmental data complicates the interpretation of results.

Santa Barbara's Channel Islands revealed the oldest skeletal remains in North America

IN 1959, archaeologists found a human femur jutting out from a rock face on Santa Rosa Island. Using the then-new technology of radiocarbon dating, they measured the age of the remains at 13,000 years—the oldest in the continent.

Researchers, experts, and retirees are finding that the 401(k) has left much to be desired

Baby Boomers, once the biggest generation, are now creating the largest wave of retirees in US history. Much of this generation is also the first to retire predominantly on the expectation that their 401(k) plans or similar tax-advantaged accounts performed well in the markets—which isn’t always the case.

Singapore, one of the world's smartest cities

A fascinating look into what makes Singapore one of the smartest cities in the world, including human-centric innovations benefitting human health such as the AI-powered "Smart Elderly Alert System."

A top Alzheimer's researcher was accused of faking results

In 2021, an investigation revealed photo manipulation in images from a seminal 2006 paper by researcher Sylvain Lesné on the role of amyloid plaques in progressive Alzheimer's disease. The revelation rocked the field, leaving many wondering whether they had tried to build on fabricated results. (Some users may experience a paywall.)

Recent evidence raises the question of whether conventional wisdom about amyloid plaques and their connection to Alzheimer's is wrong.

For 'Secret Lives of Orangutans,' David Attenborough became the oldest Emmy Award winner

In 2025, won the Outstanding Daytime Personality, Non-Daily category at 99 for his work documenting a group of apes in the jungles of Sumatra, Indonesia. The previous record had been held by Dick Van Dyke, who won at 98 for his guest appearance on "Days of Our Lives" in 2024. (Some readers may experience a paywall.)

The crypto city home to biohacking experiments

The DIY nature of biohacking gives the work an entrepreneurial feel, as seen by the emergence of community labs, at-home testing kits, and corporation-backed cities that don't necessarily require government-approved testing standards. Próspera, Honduras, created by a business of the same (first) name, was born from legislation that allowed international businesses to shave off a slice of the country to establish their own micronations.

How the buildings you occupy may affect your brain health

Beautiful spaces filled with light and natural motifs aren't just aesthetic, but likely key to your health. Researchers had study participants view photographs of two distinct buildings, one designed with more natural elements while the other featured more abstract shapes and lines. Using electroencephalograph readings of each participant, they discovered participants had less brain inflammation while viewing the "biophilic," or natural, architecture. Learn more about the interdisciplinary framework of so-called neuroarchitecture here.

Is human evolution speeding up or slowing down?

In the past 3,000 years, many populations have evolved genetic adaptations to their local environments. People in Siberia and the high arctic are uniquely adapted to survive extreme cold. The Bajau people can dive 70 meters and stay underwater for almost 15 minutes. So what are other recent changes? And will our technological innovations impact our evolution?

Explaining why animals don't cross this invisible line in Indonesia

Although the distance separating the two regions is small, East and West Indonesia have starkly different species, puzzling scientists for decades. Biogeographers use the theory of plate tectonics to explain the phenomenon, arguing the two regions...

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

The evolution of the human diet

Could eating like our ancestors make us healthier? One estimate suggests prehistoric hunter-gatherer communities obtained 75% of their calories from meat and fish.

Only half of American workers have retirement accounts at their current jobs

Most American retirement accounts are not nearly funded enough to support people living longer, healthier lives. Get the details on five individuals at different stages of life and hear how they’ve saved—or not—while expert Theresa Ghilarducci explains the current weaknesses of the retirement regime in America.

How do 'dementia villages' work?

The goal of good dementia care is to preserve a patient's quality of life as the incurable disease progresses, maximizing their ability to lead normal lives and maintain their health and dignity. Dementia villages are small neighborhoods built for people with severe dementia, with typical neighborhood haunts like salons or grocery stores staffed by people trained in dementia care, helping residents maintain a sense of autonomy and connection.