Five hazards of human spaceflight

Protecting astronauts against space radiation

Outside the protective atmosphere of Earth, astronauts are constantly bombarded by radiation, which, among other dangers, increases the risk cancer. While those of us on Earth can mitigate the effects of similar radiation by limiting exposure,...

Civilians on short-term spaceflights can experience long-term astronaut health impacts

A collection of 44 studies—primarily based on data from a 2021 tourist trip to low Earth orbit—identified immune system disruption and some kidney damage in tourists, with women appearing to recover from space travel faster than men. Return trips from Mars may require human travelers to be on dialysis.

Prolonged space travel significantly impacts multiple human body systems

Astronauts can lose 20% of their muscle mass after two weeks and 10% of their bone mass after six months in space. Decreased sharpness of eyesight and changes in neural connectivity, brain structure and gut bacteria have also been observed.

Watch what it’s like to spend a day on the International Space Station

Microgravity makes personal care more complex on the International Space Station, where stray, floating materials must be captured to prevent them from entering vents and clogging filtration vents. No-rinse shampoo, water pouches, and other strategies help minimize obstructions.

There are no established minimum fitness standards for spaceflight

Microgravity is known to cause arterial hardening, bone weakening, and other health issues, but the novelty of space tourism and the minimal exposure time for suborbital trips have limited the number of research studies. Many companies have participants sign extensive waivers to bypass the requirement of specific medical standards.

How do astronauts battle loneliness and depression?

You’re stranded hundreds of miles away from your friends and family, constantly surrounded by coworkers who also are your roommates, and you’re only allowed the shortest of walks outside. There’s also no takeout, and gravity has essentially broken up with you. You might need a little help adjusting mentally. That’s where space psychologists and psychiatrists step in, according to this article.

Watch how dozens of everyday human tasks are performed in space

This playlist features clips of astronauts aboard the International Space Station explaining how they cook, eat, sleep, and conduct research in microgravity. Other activities to pass the time, including watering plants and playing soccer, are also shown.

Research suggests the cleanliness of the ISS may make astronauts unhealthy

The International Space Station's sterile conditions deprive astronauts of the opportunity to strengthen their immune systems through microbial exposure. To address this problem, future missions may use probiotic-based cleaners and foster diverse microbes in space habitats.

Drugs in space: the pharmacy orbiting the Earth

Researchers are developing pharmaceutical solutions for astronauts, whose bodies may not respond the same way in space as they would on Earth. Similar to how microgravity causes changes to astronaut physiology, the environmental shift enables new...

Astronauts follow strict schedules to mimic Earth days and stay healthy in space

Experiencing 15 sunrises and sunsets a day while aboard the International Space Station, visitors preserve their circadian rhythms and mental health with fixed timetables. Astronauts have described sleep as living in a vacuum cleaner due to ongoing air filtration.

Astronauts exercise on the International Space Station

Astronauts maintain bone, muscle, and cardiovascular health with physical activity. It's crucial astronauts make time to exercise for approximately two hours per day. This resource offers a behind-the-scenes look at how high-intensity workouts help prevent muscle atrophy, bone density loss, and aerobic decline during months-long space missions.

Has anyone had sex in space?

Reproduction is a basic human function, and while we've spent decades in space, no research has been done into the process. With many discussing the possibility of human-occupied bases on the moon, Mars, and more, understanding how sex works outside...

Stephen Hawking on the need to explore space

Should we be content with being cosmic couch potatoes? In this interview, the late Professor Stephen Hawking lays out the case for continued and increased human space exploration, despite its cost and challenges.

Why haven’t humans reached Mars?

Mars remains the most viable interplanetary destination due to its relatively habitable orbit. There are many challenges, however, including the huge distance to Mars, the need for advanced propulsion systems, uncertainty over the impacts of long-duration space travel on astronauts, and the need for safe landing techniques and equipment to handle Martian conditions. Human-manned missions to Mars are not likely to occur until the 2030s at the earliest.

Microgravity can alter the evolution of viruses and bacteria

Experiments conducted on the International Space Station have shown that microgravity environments can delay viral and bacterial infections and induce mutations not seen on Earth. These mutations could have implications for long-term space missions and human health and suggest space can serve as a testing ground for developing new therapeutic approaches.

Space trash is making low Earth orbit increasingly dangerous for spacecraft

Millions of fragments from satellites, rockets, and other spacecraft that are no longer operational move thousands of meters per second as they circle Earth. Even a piece of debris a centimeter in size can cause mission-ending damage to space stations, telescopes, and astronauts.

What is space sickness?

Mix motion sickness minus gravity with a host of other variables, and you’ve got a recipe for space adaptation syndrome. It can hit anyone, even astronauts who escaped the issue previously. This article details the history and science behind space sickness.

Who owns outer space?

More and more material ends up in Earth's orbit, posing threats to orbiting space stations and satellites. A 1960s treaty technically made space the common property of humankind, but with increasing chances of conflict in space, things can seem anarchic. This video breaks down the brewing tensions in space.

The inhabitability of the Martian environment presents significant colonization risks

Terraforming the thin atmosphere, toxic dust, extreme cold, and lack of magnetic field is infeasible, given limitations to the size of what can be sent to Mars. NASA and SpaceX are instead exploring creating underground shelters.

Who’s in space right now?

Hundreds of people (and a few animals) have been to space since the first creatures flew past the Kármán line in 1947. There are a handful of astronauts aboard the International Space Station at any time, while others may be cresting space in...

Tardigrades have not been shown to survive all space conditions at once

A 2007 mission launched several species into low-Earth orbit, exposing them to microgravity in temperature-controlled modules. Survivability rates were high for microgravity exposure alone, but plummeted when combined with exposure to the full UV spectrum and the vacuum of space.

In 2013, an astronaut's helmet began filling with water during a spacewalk

A leak in the cooling system of Luca Parmitano's spacesuit caused water to obscure his vision and silence his radio as the International Space Station entered Earth's shadow, forcing him to feel his way back to the airlock in darkness.

Mold growth in space raises the hypothesis of life being brought to Earth

Panspermia suggests that life could be carried throughout the cosmos by asteroids, comets, and other objects, but it requires organisms that can withstand the extreme cold of space travel, stellar radiation, lack of water, and intense heat of planetary impacts. The discovery of mold on the International Space Station and experiments showing it can withstand radiation in outer space-like conditions increase the plausibility of the hypothesis.

The 1978 prediction of the Kessler syndrome popularized the risks of space trash

A paper published by NASA scientists Don Kessler and Burton Cour-Palais described a scenario where the density of objects in orbit becomes so high that collisions between them create a cascading effect of runaway debris, preventing future space travel. The risks were confirmed from returned telescope parts showing debris impacts.

Increasing space tourism may require changing the definition of astronaut

Though astronaut has been used to describe any crew member in space, civilian explorers who lack formal training have instead been dubbed "space travelers" by some. The term astronaut may one day fall out of use or be modified by ongoing media and social perceptions as the space tourism industry continues to evolve.

Eleven deaf men played a pivotal role in America's human spaceflight program

In the mid-20th century, 11 deaf men volunteered for a series of experiments that offered unprecedented insights into the effects of weightlessness on the human body. Most of the men had become deaf in early childhood as a result of spinal meningitis, a condition known to damage the vestibular system and make them less susceptible to motion sickness. For a decade, these men participated in extreme motion sickness situations, including living in a slowly spinning room, spending time in centrifuge pods designed to simulate hypergravity, and flying in parabolic flights sometimes referred to as the "Vomit Comet." (Some users may experience a paywall.)

Hear the story of a cosmonaut stranded in space after the Soviet Union collapsed

When the USSR dissolved in 1991, cosmonaut Sergei Krikalev was still aboard a space station—forcing him to remain in orbit for months longer than planned. This limited podcast series recounts the event, hosted by astronaut and pop star Lance Bass.

Space tourism rockets emit up to 100 times more CO₂ per passenger than airplanes

Rocket launches release significant amounts of water vapor, nitrous oxide, and rocket propellants, which generate greenhouse gases and air pollutants. High-altitude emissions can persist for years, affecting the ozone layer.

We don't know why astronauts get motion sick

Between 60% and 90% of astronauts get motion sick in space—and many also get motion sick during the first few days upon return. Motion sickness on Earth does not seem to correlate with whether or not astronauts get motion sick in space, so it's not possible to predict who will get ill.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

As an experiment, the first B2 mission highlighted the challenges of isolated systems

Some argue that isolation from the outside world was compromised—making the experiment a failure—when a crew member was taken from Biosphere 2 for surgery and returned hours later. This position was strengthened when it was revealed that oxygen had been pumped into the facility.

By 2030, experts estimate a 1 in 1000 chance of a plane being hit by space debris

As more satellites and spacecraft are launched, the rate of space debris re-entering Earth's atmosphere, including those that do not burn up completely, increases. International space agencies and air traffic control systems will need to coordinate to develop standardized methods and technical solutions to prevent and minimize future crisis scenarios.

Space tourism opportunities have been explored since the end of the Apollo era

In the 1970s, Rockwell International, a NASA contractor, and others investigated manufacturing passenger modules that could fit into the Space Shuttle's payload bay. NASA also opened spaceflights to nongovernment professionals, but many such programs were ended after the Challenger disaster, which killed the first Teacher in Space participant.

An unedited interview with the first person to float freely in space

Astronaut Bruce McCandless was the first person to ever float freely in space, completely untethered from a shuttle. How did he enter the field? What are his thoughts on current space travel? Listen to his experience and opinion firsthand in this 19-minute video.

You are 65,000 times more likely to be struck by lightning than to be hit by space trash

In 2023, about 1,500 pieces of space junk fell to Earth, with most consisting of payload fragmentation debris. The vast majority that falls back to Earth burns up before reaching the surface, making it three times less likely to be struck by space trash than by a meteorite.

Microgravity environments reduce muscle mass and bone density

Muscles that assist with balance and resistance to gravity are not subjected to their usual workload on the International Space Station. See the type of exercises that astronauts must complete for roughly two hours daily and learn why these movements are necessary to preserve astronauts' muscles, bones, and cardiovascular health.

Watch a documentary on what the first 10,000 days of colonizing the moon look like

Alongside the construction of the first lunar base with help from SpaceX's Starship Human Landing System, transported astronauts would establish a sustainable human presence through the construction of lunar dust shields, light-bending towers, and 3D-printed habitats.

Technologies developed for the ISS have brought benefits to people on Earth

About 93% of water used onboard the International Space Station is recycled through filtration and purification systems that have since been used in regions lacking access to clean water. Treatments to mitigate bone loss and muscle atrophy in astronauts can also help aging adults.

Visualize the impact of approximately 9,000 metric tons of satellites and space debris orbiting Earth—70% of which, including the International Space Station and the Hubble Space Telescope, do so in low Earth orbit.

Emulating Earth’s light-dark cycle is important for astronaut health and safety

Astronauts aboard the International Space Station experience 16 daily sunrises, but scientists have learned to try to promote circadian rhythms by phasing through several light settings aboard the ISS to improve astronauts’ sleep and productivity.

The science of fear

The Hidden Brain podcast team explores the science of fear by traveling to a haunted house curated by a scientist to investigate what scares us, and why some people enjoy this sensation more than others.

Five potential ways to achieve time travel

While the author discounts the possibility of traveling to the past, it lays out five hypothetical modes of catapulting into the future: speed, gravity, suspended animation, wormholes, and light. Each has some scientific basis, but none are realistic for humans. Read the article to learn where they offer promise and where they fall short.

How a deadly antarctic expedition turned poisonous

A deadly 1912 scientific expedition to the Antarctic took a turn for the worse when the expedition team's leader turned to man's best friend to fuel their journey. This 21-minute podcast episode provides a glimpse into the real-life dangers of...

Learn about ionizing radiation and see the most radioactive places on Earth

The average person is exposed to radiation every day, though most of it is either harmless non-ionizing radiation or ionizing radiation at doses too small to significantly affect an individual. The highest doses of ionizing radiation are received by smokers due to the radioactive polonium and radioactive lead in tobacco products.

Are smart cities a dumb idea?

Smart cities require vast troves of data to run, making their systems attractive to hackers. Listen to this one hour podcast to learn about the risks and what is being done to mitigate them.

Particles found in Martian air pose significant risks to human lungs

Ultrafine dust, just 3 micrometers wide, is small enough to bypass lung defenses and enter the bloodstream, where its highly reactive chemicals can cause thyroid disease. Silica in the dust can also cause silicosis, a chronic and incurable lung disease.

Listen to why extensive ear rinsing can create problems

The clinician who hosts this podcast discusses how his patient developed swimmer's ear after he flooded his ears with water during his daily showers, ostensibly to clean them. The resulting itchy, painful ears were the result of removing protective earwax in the ear and also altering the typical pH of the ear.

Watch an expert's take on the rare disease hantavirus—and why it's not of great concern to the general population

This rare zoonotic disease, transmitted to humans primarily through infected rodent droppings, urine, or saliva, is rarely spread between people. The disease was of particular concern in spring 2026, when an outbreak occurred on a 150-person cruise ship, prompting a flurry of action, including contact tracing for passengers in their home countries. The disease can be fatal. But early care—primarily oxygen support—can help patients survive.

Take a virtual tour of the International Space Station

The ISS is the largest human-made object in space. Its modules were meticulously connected by robotic arms and astronauts during slow, careful spacewalks, creating a structure with over eight miles of electrical wire.

Watch 'Last Week Tonight' explore the risks of 'forever chemicals,' a group of human-made chemicals used in everyday products to make them resistant to water, stains, grease, and heat. (Warning: language.)

Per- and polyfluoroalkyl substances (PFAS) are a group of human-made chemicals used in a wide range of products due to their unique properties. However, because they can persist in the body and environment for thousands of years, they've earned the moniker "forever chemicals"—and have been linked with numerous health risks.