Autism Spectrum Disorder, defined in 2013, was previously categorized as numerous disorders.

Roughly 1 in 125 people have autism spectrum disorder globally

The disorder has been increasingly diagnosed as its definition has grown broader and as clinicians have become more adept at identifying it—with some estimates suggesting the figures are much higher. These figures include people across the spectrum, some of whom live mostly independent lives, while others require life-long care and assistance.

Autism rate increases are mostly among those with milder symptoms, not individuals with severe symptoms

Broader case definitions and better screening are typically now detecting more milder cases of autism rather than individuals who have severe impairments (who could be categorized as having profound autism). Profound autism rates, an autism researcher says in this article, have stayed proportionately steady.

A growing number of autism researchers with the disorder are reshaping the field.

1 in 31 kids in the US has autism

That figure comes from an analysis published by the US Centers for Disease Control and Prevention based on data gathered on eight-year-olds in 2022. Its figures mark a significant increase from 2000, when the estimated autism figure was one in 150, but improvements in diagnosis and changes to the disease criteria that broadened the diagnostic criteria are widely believed to be driving that increase.

Autism occurs among women, too

Males have higher rates of diagnosed autism than females, but recently scientists and people with autism have been exploring if females have been disproportionately missed in screening and if girls are perhaps masking their symptoms better, leading to missed diagnoses.

Autism and ADHD may have overlapping symptoms and someone can have both disorders

This video explores similarities and differences between these two disorders, which both have genetic causes. Challenges with attention, hyperactivity, and impulsivity are typical of ADHD. Fidgeting, problems picking up on social cues, emotional dysregulation, and being oblivious to time may occur with both disorders—though the impetus for these behaviors may differ.

Diagnosis as an adult can have huge benefits, including helping someone with ASD to feel real

This first-person account of a woman diagnosed with autism at age 31 covers her experience of why it was useful for her to receive her diagnosis as an adult and how it helped her to understand her life and her feelings of 'being an imposter.'

The sibling of someone with autism has a 20% chance of developing ASD

The disorder is strongly linked with inheritance, and research suggests that if one child has ASD, there's a one in 5 chance the next child will develop autism, which is seven times more likely than the general population.

Risk factors linked with ASD include older parents, preterm births, and toxic prenatal exposures

Though researchers agree that there is a strong genetic component to ASD development, certain environmental factors heighten that risk, with studies suggesting older parents, premature birth, maternal obesity, and air pollution exposure in utero all elevate risks of ASD development. There is no connection between receiving vaccines and ASD development.

Autism research has faced significant cuts under Trump

One of the largest areas of halted research was at the Department of Education where its Institute of Education Sciences had studies underway focused on developing and evaluating school-based interventions for students with autism. DOE was significantly cut back as part of federal government layoffs.

Gene expression patterns are similar between ASD, schizophrenia, and bipolar disorder

Postmortem brain tissue analysis suggests there are genetic and epigenetic similarities between individuals with autism, schizophrenia and bipolar disorder. All three conditions appeared to have activation of genes in astrocytes and suppression of specific genes that function at the junction between neurons, called synapses. (Some users may encounter a paywall.)

Even if you have some ASD-linked gene variations you may not develop ASD

Individual environment and life experiences affect how genes perform in the body, potentially adding methyl groups to DNA that affect their function and turning genes on and off—which may heighten or reduce disease risk.

Researchers are exploring neural links between Alzheimer's and autism

Recent DNA sequencing and molecular biology studies suggest that similarities in genes, neural circuitry and patterns of disease warrant further exploration to potentially better understand both conditions and how to treat them. (Some users may encounter a paywall.)

Watch this behind-the-scenes interview about the first person ever diagnosed with autism

Two reporters from The Atlantic tell the story behind their effort to track down the first diagnosed autism patient, Donald Gray Triplett, in Forest, Mississippi, and how his life turned out decades later.

Roughly 10% of the world has SSAD—SAD’s milder, nonclinical cousin

Subsyndromal affective disorder is diagnosed when someone exhibits two of the nine major criteria for depression (but not more than five) as a result of seasonal changes. While it is milder than primary SAD, SSAD is still significant and impacts millions.

Some UK doctors pushed for broad 'do not resuscitate' orders for autistic adults during COVID

The controversial push was to create such orders without individuals' or their families' consent, underscoring modern-day prejudice against people on the spectrum.

American medical organizations rescind recognition of diagnosis cited in police custody deaths

American medical organizations have rescinded their recognition of a syndrome whose theory stemmed from discredited research. This article explores the history and implications of "excited delirium syndrome," a medical condition that can reportedly...

'Love on the Spectrum,' a popular Netflix reality show, is following people on the autism spectrum as they navigate romantic relationships

This is one of Netflix's biggest shows, something this podcast says is due partly to the fact that the series both scratches the itch for people who enjoy reality dating viewing and the program is conducted in a nonexploitative, sensitive way that makes viewers truly want the best for the people navigating these situations.

SAD uniquely affects people with attention-deficit hyperactivity disorder

Those with ADHD—chronic issues with attention and executive function—are primed for SAD. Many are disproportionately evening chronotypes (more awake in the evening), have a delayed sleep phase, and have low sensitivity to light in the morning. This podcast explores the overlap between these two groups.

Common genetic disorders

As research continues, it's clear that disease and genetics go hand in hand. Here's a selection of 50 National Human Genome Research Institute (NHGRI) articles providing basic information on genetic, orphan, and rare diseases caused by mutations in DNA sequences, whether inherited from parents or brought about by outside factors.

Learn about the more than 100 known autoimmune diseases

Explore this resource with summaries and related resources for the dozens of autoimmune diseases defined in the medical literature. Many of these disease write-ups also have interviews with a patient with the disorder—offering a personal take about challenges, advice, and lifestyle effects.

SAD 101 from the folks at NIMH—where the condition was first identified

Norman Rosenthal led the team at the National Institute of Mental Health that first identified and described seasonal affective disorder in 1984. This 101 from NIMH explores the basics of the condition, from who develops it to how it is treated.

Read Norman Rosenthal’s original 1984 paper describing SAD

The study helped formalize research and diagnosis of seasonal affective disorder, catalyzing the development of therapies (like bright light) and leading to broader adoption of effective treatments. It also helped connect the influence of light and seasons on biological mechanisms in the human body, spurring exploration of circadian rhythms.

Could all mental health disorders have a unifying 'p-factor'?

Some researchers have argued in the past couple decades that all mental health disorders may have a unifying dimension—a theoretical "p-factor" that is common across mental illness, but life experiences and behaviors influence if and how illness manifests. Proponents point to similarities across different disorders, while detractors argue that such connections are largely exaggerated.

Schizophrenia is challenging to diagnose and treat

The disorder is diagnosed by a clinician who observes behaviors and medical history and may run additional tests to rule out other explanations for symptoms including physical injury or other mental health disorders. But, ultimately, it's largely a diagnosis of exclusion—since there is no definitive test for the disease. Antipsychotic medications can help control its symptoms for some patients, but there is no cure for schizophrenia.

Scientists identify hundreds of genes responsible for OCD

Researchers analyzed the DNA of more than 53,000 people with OCD and identified 30 areas in the genome linked to the disease, containing 249 genes of interest. Of those, several were linked to other brain disorders, paving the way for genetic treatments of various mental illnesses.

Here’s how different genetic disorders get passed on

The human genome is complex, as identified by the Human Genome Project. This article digs in to genetic disorders, the most common ones, and how they are diagnosed.

Having five of nine key symptoms constitutes a major depression

Before professional standards were adopted, practitioners used varying criteria to diagnose mental health disorders. By the 1970s, more objective lists were organized, culminating in this list of polythetic criteria—a list of symptoms where no single criterion is required, but a minimum number must be present.

There are multiple types of multiple sclerosis—they differ by attack patterns

When your immune system targets the nervous system, this can cause new or worsening symptoms and the development of scarring or damage within the central nervous system. Relapsing-remitting MS is the most common type of the disease—it includes progressive bouts of attacks that occur months or years apart.

Social media addiction, though not a clinical diagnosis, refers to the idea that infinite scroll, notifications, and algorithms override one's ability to stop using them.

In 2019, videos on TikTok convinced children they had Tourette syndrome

Right before the COVID-19 pandemic, an "outbreak" of Tourette syndrome was attributed to videos from a German TikToker who documented his life with the condition. The children experiencing the symptoms all had the same tics, which experts say was a case of mass sociogenic illness, also referred to as mass hysteria.

The term schizophrenia was coined by Swiss psychiatrist Eugen Bleuler in 1908

He launched the word during a lecture at the German Psychiatric Association in Berlin. In his talk he focused on the splitting of psychic functioning as a defining feature of the disease and noted it wasn't associated with dementia or factors like early puberty onset.

The Individuals with Disabilities Education Act improved the lives of many children with disabilities

Before the IDEA, many individuals lived in state institutions and received little education—only one in five attended public schools. Today, US public schools now educate over two-thirds of children with disabilities in general education classrooms.