Listen to Sam Altman's 17 startup principles, including 'take risks on high-potential candidates.'

Stanford’s archive of lectures about creating a startup includes advice from Y Combinator notables such as former YC president and OpenAI CEO Sam Altman and YC Cofounder Paul Graham.

Before becoming the head of OpenAI, Sam Altman was the president of Y Combinator—a startup accelerator company that supported companies like Airbnb, DoorDash, and Coinbase. In 2016, Altman interviewed Zuckerberg about creating Facebook and its growth over time. Zuckerberg said that, unlike other companies (think: CourseMatch), Facebook kept growing and adding new features, which prevented the app from becoming obsolete.

Led by CEO Sam Altman, OpenAI's mission is to "ensure artificial general intelligence benefits all of humanity" by making its products open to all users. In 2023, the $86B company behind the chatbot ChatGPT consisted of a for-profit arm under its nonprofit governing board.

Many of the philosophies that the leaders of Y Combinator have infused into the program’s portfolio companies have become the playbook for building the next big thing, such as its focus on founder personality and more.

Some argue that ideal startup employees have to be better than the average worker at managing uncertainty, acting with an "ownership" mindset rather than being a cog in the machine, and pushing limits.

Daniel Ha is a venture capitalist who built a suite of AI agents to boost his productivity, both professionally and personally. At his VC firm, a troupe of agents gathers data on startups and analyzes it from competing perspectives to produce a confidence score. When his dad was diagnosed with cancer, Ha used an oncology-trained AI to help him understand the condition.

Hear YC President and CEO Garry Tan talk about why he values earnesty and excellent communication skills in YC founders, his thoughts on AI, and more in this unexpectedly deep and in-depth interview.

In 2024, Y Combinator cofounder Paul Graham popularized the idea of "founder mode" when he wrote a viral manifesto in response to a talk that Airbnb CEO Brian Chesky gave about leadership styles. Graham positioned the concept of founder mode as the opposite of manager mode—when founders hire executives and middle managers to run their companies and make decisions that Graham says are better left to founders.

In 2024, Y Combinator Cofounder Paul Graham wrote a viral manifesto of sorts about a strategy he calls "founder mode." It's the opposite of what Graham calls "manager mode," which allows founders to hire executives who he says ultimately run the company into the ground.

That's according to a new study from Wharton. Y-Combinator, perhaps the most famous startup accelerator, currently has 16 alumni companies trading on the public market. But not every entrepreneur who joins a startup accelerator makes it big.

Tesla and X CEO Elon Musk, OpenAI CEO Sam Altman, LinkedIn founder Reid Hoffman, and others are getting into politics. From Musk’s role in President Trump’s second term to Hoffman’s spending on former Vice President Harris’ presidential campaign, more tech CEOs are expanding into politics. This podcast episode by WBUR and American Public Media discusses what the impact could be with so many tech figures engaging in American politics. Listen here.

An interview with Alphabet CEO Sundar Pichai warns that the trillion-dollar surge in AI valuations may contain clear signs of irrationality, echoing past tech bubbles. He says no firm—including Google—would be immune if the boom cools or bursts.

Y Combinator also recently increased its number of cohorts or “batches” per year from two to four. Its leaders cited artificial intelligence’s rise as a reason for the increase.

The short-term rental CEO learned hard lessons through the pandemic, specifically around a culture focused on management and not building products. In the fall of 2024, Chesky gave a well-received speech at a startup conference that prompted debate in the startup world. He summarizes the talk here.

Radically reducing the cost of rockets and innovating totally new space vehicles originated in the singular force of Elon Musk's vision. In this podcast, Founders creator David Senra shares what he learned reading a book about SpaceX's beginnings, highlighting Musk's audacious refusal to follow industry conventions and promotion of a culture of action and speed. Learn more insights from the founder here.

- Microsoft cofounder Paul Allen (1953–2018)

Those programs, such as Y Combinator and Techstars, not only offer expert advice to founders, but also seed funding in exchange for equity. The goal is to help young startups learn from successful companies, making it more likely they attract venture capital.

Prior to Palantir's public listing in 2020, CEO Alex Karp did not give many interviews. In a rare interview from 2009, Karp discussed the dominance of American technology, his academic background, and the founding idea of Silicon Valley entrepreneurs as key players in aiding the fight against terrorism.

Author, editor, and thinker Kevin Kelly makes an argument for optimism. Not only as a personal philosophy, but as a moral obligation, focusing on the need for optimism in overcoming challenges. Drawing examples ranging back to the Wright brothers,...

As Anthropic is a public benefit corporation, its board is tasked with making sure that AI tools are developed to help people and society thrive. Members of its Long Term Benefit Trust hold no equity in the company, but make up a majority of the board and can act to maintain Anthropic's public benefit purpose.

Palantir has been criticized for its close proximity to conservative politics, including the company's partnership with ICE, cofounder Peter Thiel's long track record of large donations to Donald Trump's campaigns, and the company's support for Israel. But its leader, Alex Karp, is a self-proclaimed progressive with a PhD in social theory. For many, Karp's background and leadership are a paradox for Palantir.

Also known as a16z, the firm has invested in companies such as Airbnb, Facebook, and Lyft since its founding in 2009. A podcast episode offers a deep dive into how the firm got started and became the industry disruptor it is today.

The tech company founder and CEO has a wide variety of leadership principles he has kept consistent while building multiple different companies, including eschewing middle management and using the "idiot index," a formula he uses to identify manufacturing inefficiencies.

Mark Zuckerberg became the youngest self-made billionaire in 2006 at 23 years old when Facebook held its initial public offering. In January of 2026, three AI startup founders—Brendan Foody, Adarsh Hiremath, and Surya Midha—broke Zuckerberg's record and became billionaires at 22 years old.

That’s lower than the most elite universities and colleges in the world—but insiders have some tips about how applicants can have the best shot of being accepted to the selective startup accelerator.

In addition to cofounding Y Combinator and other companies before it, Paul Graham is a prolific writer and artist. He chronicled many of his thoughts while building Y Combinator in a series of dozens of candid essays, all of which you can read in an online archive.

With Peter Thiel's "Monopoly Theory," the Founders Fund partner argued that investing in companies that create new categories, rather than those that compete with other businesses in existing ones, is a best practice in venture capital.

In 2017, Dalio gave a TED Talk called "How to Build a Company Where the Best Ideas Win," which largely focused on Bridgewater's highly documented company culture and leadership principles. Dalio's TED Talk focused on one of his most well-known principles, "radical transparency," as a way to create an idea meritocracy.