Sam Altman was shocked that people still went to Blockbuster after Netflix started shipping DVDs, unlocking an insight about human reluctance to change behavior.

AI, as a concept, has been around since at least the 1950s, but it's only in the last year or so that the technology has been able to equal humans at many tasks -- and in many cases surpass humans. In this podcast, mathematician and computer scientist Stephen Wolfram provides an AI 101, explaining how we got here, how highly advanced chatbots like ChatGPT work, and what our world is in store for next.

As AI becomes a bigger part of our lives, what does that mean for the future of humanity? The podcast Entanglements hosts a pessimistic former OpenAI employee and an optimistic Princeton professor to discuss whether AI brings dystopia or a brighter future.

Before becoming the head of OpenAI, Sam Altman was the president of Y Combinator—a startup accelerator company that supported companies like Airbnb, DoorDash, and Coinbase. In 2016, Altman interviewed Zuckerberg about creating Facebook and its growth over time. Zuckerberg said that, unlike other companies (think: CourseMatch), Facebook kept growing and adding new features, which prevented the app from becoming obsolete.

An interview with Alphabet CEO Sundar Pichai warns that the trillion-dollar surge in AI valuations may contain clear signs of irrationality, echoing past tech bubbles. He says no firm—including Google—would be immune if the boom cools or bursts.

From ChatGPT to DALL-E, 2022 saw the mainstream emergence of artificial intelligence for consumer use. Here's how these platforms will disrupt today's five biggest tech companies—Apple, Amazon, Meta, Google, and Microsoft.

For years, Google was the cutting-edge of the AI world, including the development of the Transformer—the basis of contemporary AI chatbots. But since OpenAI debuted ChatGPT in 2022, the company was had to play catch-up. This is a four-hour deep dive into Google's AI history.

The short-term rental CEO learned hard lessons through the pandemic, specifically around a culture focused on management and not building products. In the fall of 2024, Chesky gave a well-received speech at a startup conference that prompted debate in the startup world. He summarizes the talk here.

Led by CEO Sam Altman, OpenAI's mission is to "ensure artificial general intelligence benefits all of humanity" by making its products open to all users. In 2023, the $86B company behind the chatbot ChatGPT consisted of a for-profit arm under its nonprofit governing board.

Berkshire Hathaway chairman Warren Buffett is one of the many people who’ve come face-to-face with the downside effects of AI, and in particular, deepfakes. He was recently shown a deepfake of himself in a video, which caused him to worry about how bad actors will take advantage of the technology.

2022 was the year AI broke onto the scene, with applications like ChatGPT amazing users with its ability to generate realistic-sounding answers. Technologist Arvind Narayanan presents a clear-eyed view of what the technologies can (and can't) do.

Most AI systems are so-called "black box" models, where we only see inputs and outputs while the inner workings remain obscure. This piece, written prior to the launch of ChatGPT, cautions developers to know why and how a system produces its results, and not to sacrifice explainability for accuracy.

- Apple CEO Tim Cook (1960 - present)

Tesla and X CEO Elon Musk, OpenAI CEO Sam Altman, LinkedIn founder Reid Hoffman, and others are getting into politics. From Musk’s role in President Trump’s second term to Hoffman’s spending on former Vice President Harris’ presidential campaign, more tech CEOs are expanding into politics. This podcast episode by WBUR and American Public Media discusses what the impact could be with so many tech figures engaging in American politics. Listen here.

Workers, particularly in marketing, are experiencing mental fatigue in the workplace due to expectations—often unspoken—that they should use AI to multitask beyond their comfort levels. Many feel they are underperforming if they don't embrace this technology. This situation differs from typical burnout. This podcast discussion suggests that this "brain fry" tends to intensify when employees are required to use more than three AI tools.

Stanford’s archive of lectures about creating a startup includes advice from Y Combinator notables such as former YC president and OpenAI CEO Sam Altman and YC Cofounder Paul Graham.

Dalio argues that there aren't new events in history, per se, and that people are taken by surprise by events because they just haven't happened in their lifetimes—not because they are actually novel.

The most consequential business stories involve intense rivalries. The story of Netflix versus Blockbuster is one of those: an agile upstart versus an entrenched incumbent. This nine-part podcast explores the key strategies and pivotal moments in the rivalry that upended the entertainment business, setting the stage for the streaming wars.

Rodney Brooks wrote several decades ago about the boom and bust cycles of artificial intelligence. Starting from the 1950s excitement over ENIAC's multiplication through the second launch of then-novel neural networks, Brooks suggests AI progresses incrementally despite the hype.

In a 1999 shareholder letter, Bezos wrote, "I constantly remind our employees to be afraid, to wake up every morning terrified. Our customers have made our business what it is, and we consider them to be loyal to us – right up until the second that someone else offers them a better service." Motivated by fear, the entrepreneur advocates consistent innovation, experimentation, and improvement to create a better customer experience.

Daniel Ha is a venture capitalist who built a suite of AI agents to boost his productivity, both professionally and personally. At his VC firm, a troupe of agents gathers data on startups and analyzes it from competing perspectives to produce a confidence score. When his dad was diagnosed with cancer, Ha used an oncology-trained AI to help him understand the condition.

Radically reducing the cost of rockets and innovating totally new space vehicles originated in the singular force of Elon Musk's vision. In this podcast, Founders creator David Senra shares what he learned reading a book about SpaceX's beginnings, highlighting Musk's audacious refusal to follow industry conventions and promotion of a culture of action and speed. Learn more insights from the founder here.

The ongoing development and refinement of new AI models requires larger datasets and processing more parameters between words and subwords to improve the accuracy of generated content. New startups are expected to harness this technology to provide unthought-of products and services.

Palantir cofounder Joe Lonsdale was an editor of the Stanford Review (which Peter Thiel founded), and Thiel became a mentor to Lonsdale. The two discussed shared sentiments about the importance of developing Palantir to maintain a largely American global order, as well as cultural revolutions.

One of Ray Dalio's principles is to constantly be challenged by smart people. He says thoughtful disagreement is key to becoming smarter and making better, more thorough decisions.

Generative AI is the latest entry in a recurring cycle where emerging tools start as "AI" until they become common software, like databases or machine learning. Generative AI and large language models may be the next platform shift after smartphones and the Web.

Space has been called the final frontier of innovation and investment for decades. Many innovators say the ocean is the new space, the vast majority of whose hidden depths remain obscure. In this podcast episode, business-minded experts discuss the opportunities founders see in the ocean, including seagrass restoration, underwater cable networks, and more.

In a conversation with Bloomberg, YouTube CEO Neal Mohan maps out how the company is taking what it’s learned thus far and embedding itself into the “lean-back” TV viewing experience.

AlexNet is a neural network created in 2012 that laid the groundwork for modern AI models. Before AlexNet, the ideas behind neural networks existed, but the computational power to run them didn’t.

Since his success shorting subprime mortgage-backed securities in 2008, Burry's positions have often become influential, sparking conversations on platforms like X. In 2025, Burry drew attention for betting against Nvidia and Palantir for being overvalued companies.

Many of the philosophies that the leaders of Y Combinator have infused into the program’s portfolio companies have become the playbook for building the next big thing, such as its focus on founder personality and more.

Prior to Palantir's public listing in 2020, CEO Alex Karp did not give many interviews. In a rare interview from 2009, Karp discussed the dominance of American technology, his academic background, and the founding idea of Silicon Valley entrepreneurs as key players in aiding the fight against terrorism.