A massive stockpile of 2.3 million doses of penicillin was readied by a coalition of pharmaceutical and chemical companies ahead of D-Day to treat soldiers who might be wounded on the battlefield.

By June 1944, Allied stockpiles included 2.3 million doses of penicillin—enough to ensure that every soldier wounded during the pivotal Normandy landings could receive treatment.

By 1943, the US War Department made penicillin its second-highest priority—just after the Manhattan Project. Producing enough of the antibiotic for the D-Day invasion became a central mission of Allied science and industry.

Despite its promise, US production of penicillin remained minimal in 1942—enough to treat fewer than 100 patients nationwide. Within two years, output expanded into millions of doses to supply troops for D-Day.

When penicillin became widely available in the 1940s, newspapers and doctors alike celebrated it as a “wonder drug” that could cure infections once considered fatal.

Alexander Fleming, Howard Florey, and Ernst Chain received the 1945 Nobel Prize in Physiology or Medicine for discovering and developing penicillin.

In 1939, a team at Oxford—including Howard Florey, Ernst Chain, and Norman Heatley—revived Fleming’s forgotten discovery. Using makeshift equipment like bedpans and milk churns, they purified enough penicillin to prove it could treat deadly infections.

Experts widely rank penicillin’s discovery among the most important advances in medicine. It launched the antibiotic era, transformed once-deadly infections into treatable illnesses.

Fleming is credited with the discovery, but since he was not a chemist, he was unable to purify and scale the highly unstable compound's production. This task would fall to Florey and Chain, who crucially developed the antibiotic into its scalable form.

On D‑Day, over 156,000 American, British, and Canadian troops assaulted five heavily defended beaches along a 50‑mile stretch of northern France. Supported by nearly 3 million men, 1,200 warships, and 13,000 aircraft, the successful landings paved the way for the liberation of Western Europe and decisively shifted momentum against Nazi Germany.

Anna Dumitriu's bioart piece was created to commemorate the 75th anniversary of the first use of penicillin in a human patient and intends to raise awareness about the rapid development of antibiotic-resistant pathogens by using bacteria that have essentially been transformed into their pre-antibiotic era state.

Alexander Fleming’s discovery of penicillin revolutionized modern medicine. But the same man who pioneered the development of antibiotics also recognized that bacteria could make sntibiotics obsolete if they were used irresponsibly. This story sheds light on Fleming’s discovery—and on his prophetic warning about antibiotic resistance.

Processed foods had existed since the 19th century, but they began infiltrating the mainstream during World War II, with foods designed to last on the battlefield for days. After the war, food companies saw great potential in the relatively cheap foods aimed at busy households.

Research projects funded or sponsored by the military led to the development of active dry yeast to make bread easier to bake and an improved version of dehydrated cheese, which would be used in powdered cheese snacks. Freeze-drying, which had been used to ease the transport of blood plasma to battlefields, where it would be reconstituted with water, was later used on fruit for cereals.

The vast majority of bacterial treatments were developed during the "Golden Age of Antibiotics," an era of rapid innovation and drug discovery that led to the reduction of millions of deaths worldwide. Since 1970, only eight new antibiotic classes have been discovered.

While it was indeed the first industrialized war, medical science had yet to catch up on the battlefield. This nearly eight-minute video sorts through the contents of a World War I stretcher-bearer's satchel. A modern doctor and ex-officer assesses the bag's various medical tools for performing first aid on the battlefield.

The 1942 Victory Book Campaign—sponsored by the American Library Association, the Red Cross, and the USO—asked the public to donate books to both train and entertain troops. The national campaign exceeded its goal, collecting more than 10.2 million books.

In the early 20th century, pneumonia was a top cause of death worldwide, often fatal without effective treatment. Penicillin turned a once deadly infection into one of the most treatable bacterial diseases.

Between May  26 and June 4, 1940, Operation Dynamo evacuated roughly 338,000 Allied soldiers from Dunkirk, France. Crucially, over 700 civilian “little ships”—yachts, fishing boats, pleasure craft—ferried troops from the shallow beaches to larger vessels, embodying a national rescue effort and preserving the core of Britain’s army for the war ahead.

Between 1840 and 1883, scarlet fever was among the leading causes of childhood death in the United States, with case fatality rates ranging from 15% to 30%. Today, thanks to antibiotics like penicillin, the mortality rate is below 1%.

The US launched Project Paperclip in 1946, covertly recruiting over 1,500 German scientists to advance American military and space programs. Among them was Wernher von Braun, a key architect of the V-2 rocket who later became instrumental in NASA’s Apollo missions. While these scientists accelerated technological breakthroughs, their recruitment raised moral debates about overlooking wartime affiliations in the name of progress—questions that remain unresolved today.

In America, life was transformed by total war: sixteen million service members left civilian life, while massive industrial production demanded labor. Women, minorities, and teens filled factories, fueling boomtown growth and breaking social barriers. Simultaneously, rationing, recycling drives, Victory Gardens, ration stamps, blackout drills, and war bond campaigns permeated daily routines.

Antibiotics have long been used in agriculture to treat diseases in animals and plants. However, antibiotics are also often misused, to treat non-bacterial diseases, to encourage growth in animals, and more. This expansive use of antibiotics has become one of the primary sources of the emergence of new superbugs.

See how US comic books, alongside international counterparts, served as powerful wartime propaganda tools from 1941 to 1945—boosting morale, promoting war bonds, and demonizing Axis powers through the use of iconic heroes and patriotic messaging.

During World War I, the United States government commissioned eight artists to accompany American Expeditionary Forces to Europe to sketch and document what they saw. Drawing tanks, soldiers, shattered villages, and even German prisoners of war, the artists preserved much of the war as a matter of historical record and to rally support back home.

Chef Boyardee wasn’t just a grocery store staple—it was once a key supplier for US troops in WWII. Founded by Italian immigrant Hector Boiardi, the company produced thousands of canned pasta rations daily.

Creating the first atomic bombs demanded breakthroughs in physics, engineering, and logistics—uniting elite scientists with tens of thousands of workers across the US. This in-depth history explains how the Manhattan Project overcame those challenges.

Soldiers settled into trenches to defend themselves against shrapnel and bullets, but weapons such as mustard gas crawled along the ground and settled in these low-lying areas. Here are 10 items that could have helped you survive the trenches, according to this article.

The increased use of antibiotics combined with an aging population, is projected to result in an almost 50% increase in global deaths from antimicrobial resistance each year. At the same time, antibiotic use for livestock is expected to increase by 30% over the same time frame.

During World War II, German submarines (also known as U-boats) prowled the Southern coast of the US in 1942 and 1943, sinking more than 60 ships and killing 600 Allied soldiers. The campaign is less well-known, since the major battles in Stalingrad and Midway happened at the time. Several of these submarines and the ships they sank are now popular diving spots.

Industrialization brought massive changes to warfare during the Great War. Newly-invented killing machines begat novel defense mechanisms, which, in turn spurred the development of even deadlier technologies. Nearly every aspect of what we would consider modern warfare debuted on World War I battlefields. Starting with soldiers on horseback carrying lances and ending in poison gas, machine guns, and aerial battles, this gallery shows the first tools of modern warfare.

Rockwell initially pitched the "Four Freedoms" project to the US Ordnance Department, but was rejected. Rockwell's editor at the Saturday Evening Post, however, loved the idea and published the images across four consecutive issues. After they became a sensation, the Saturday Evening Post partnered with the US Department of the Treasury to send the paintings on a 16-date national tour, which raised $133M in war bonds and stamps. Meanwhile, the Office of War Information printed four million sets of the posters with "Buy War Bonds" emblazoned on them.

In 18th- and 19th-century outbreaks, some New England families lost as many as eight children to diphtheria, and fatality rates in hospitals often topped 60%. The invention of antitoxins, penicillin, and vaccines dramatically reduced deaths.

In 1856, a chemist accidentally discovered mauveine, the world's first synthetic dye, while trying to make quinine to treat malaria. The synthetic dyes that followed helped reveal germs under microscopes, paving the way for modern imaging techniques and breakthrough treatments, such as antibiotics.

Slimy, squishy, slow-moving, and heroic? Slugs are land-dwelling mollusks known mostly for causing havoc in our gardens. But during World War I, slugs saved numerous soldier's lives as poison gas detectors. Learn how the unpleasant creatures earned their stripes in the battle to protect soldiers from chlorine, phosgene, and mustard gas as organic detectors.

Why don't we just develop new antibiotics? In part, it's a complex scientific challenge, but market incentives also play a significant role. It can be time consuming, expensive, and most notably, we should use as little as possible to avoid driving further antibiotic resistance.

To boost his squad’s morale during World War II, squadron commander J. Hunter Reinburg developed a method for making ice cream on the fly: Empty ammo cans filled with ingredients were flown at altitudes high enough for them to freeze.

The “petites Curies” allowed medical professionals to identify the severity of wounds without transporting soldiers to medical facilities, expediting treatment and saving lives. The efforts of Curie and other women led to expansions in their rights after the war.