Volcanoes in the 1340s likely helped trigger the Black Death

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

The list of historic volcanic eruptions includes the 1883 blast from Krakatau, which killed more than 36,000 and was the first such event to be documented in real time, thanks to the telegraph.

The bubonic plague spread in three waves over 600 years

The Black Death refers to the first wave of the plague, which swept through Europe in the 14th century and killed 25 to 50 million people. Caused by the bacterium Yersinia pestis carried by fleas (often on rats), the human toll was roughly one-third of Europe's population at the time.

Hear how the Black Death reshaped Europe's economy

The Black Death killed tens of millions across Europe, but the labor shortages that followed shifted economic power. With fewer workers available, survivors demanded higher wages and better conditions—sparking what historians call a medieval “Golden Age of Labor.”

Europe’s first recorded influenza pandemic swept the continent in 1580

The 1580 influenza pandemic, traced from Asia to Africa and into Europe, became the first flu outbreak clearly documented across the continent—killing tens of thousands and highlighting influenza’s potential for rapid global spread.

Measles reached global transmission during the 15th- and 16th-century Columbian exchange

Devastating diseases like smallpox, influenza, measles, and other viruses were largely introduced into the Western Hemisphere beginning with the 1492 arrival of Christopher Columbus and the ensuing age of exploration.

Mount Vesuvius' ancient Roman eruption may have literally boiled blood

Mount Vesuvius erupted in 79 CE, sending ash and debris far and wide, burying several cities and the people inside them. This article details the various ways the blast killed those in Herculaneum. This seaside town was hit with the same ash and debris as Pompeii, and it was also hit by a wave of volcanic gases estimated to be more than 500° Fahrenheit, about 260° Celcius.

Cholera went global thanks to global trade

The first cholera pandemic grew from an outbreak in India, in 1817. Scientists suggest it spread from there throughout the continent and onward to Africa, Russia and Europe through the poop of traders.

View the 10 biggest volcanic eruptions in recorded history

The Mount Tambora eruption in 1815 was the deadliest and released so much sun-blocking ash and gas that 1816 became known as “the year without summer.” The resulting global food shortages are estimated to have killed over 71,000 people.

Human records of influenza stretch back more than two millennia

Accounts of flu-like illness appear as early as 412 BCE, when Hippocrates described a sudden wave of cough and fever. Centuries of recurring outbreaks culminated in the first clearly documented pandemic in 1580, spreading from Asia into Europe and Africa.

Human records of influenza stretch back more than two millennia

Accounts of flu-like illness appear as early as 412 BCE, when Hippocrates described a sudden wave of cough and fever. Centuries of recurring outbreaks culminated in the first clearly documented pandemic in 1580, spreading from Asia into Europe and Africa.

Supervolcanoes can eject enough material to fill one-fourth of the Grand Canyon

Although extremely rare, their released material can trigger winters by blocking the sun and cooling the Earth’s surface for years. The Toba supereruption 74,000 years ago disrupted food chains and reduced the human population to a few thousand.

New evidence suggests the eruption's victims died as their blood boiled

While most Pompeii victims suffocated or were crushed, spectroscopic analysis of bones from a nearby town indicates something more extreme: exposure to superheated gas that instantly boiled blood and caused deadly internal trauma.

Europeans' arrival to America brought disease to Indigenous populations

Indigenous people lived in the Americas for centuries before the arrival of the first Europeans in the 15th century. Their arrival was disastrous for Native tribes; in addition to being enslaved and losing their land, they had no natural immunity to the diseases brought by colonists. Eventually, up to 95% of the Native American population was killed by illnesses including typhus, chickenpox, and cholera, an event now known as the Great Dying.

How powerful was the volcanic blast that destroyed parts of ancient Rome?

This article details how strong Mt. Vesuvius' powerful 79 CE blast may have been. Pompeii lay a bit further from the volcano's slopes than Herculaneum, a smaller seaside city. While Pompeii was mainly destroyed by ash and lapilli—glassy fragments of lava ejected during volcanic eruptions—Herculaneum was first hit by a scorching pyroclastic cloud of volcanic gas and other matter.

Measles evolved from an ancient cattle disease, branching off as recently as 3,000 years ago.

Underwater volcanoes significantly contributes to marine extinctions during the Triassic period

An analysis of ocean basins in the Tibetan Plateau helped identify three major periods of volcanism—250-248, 233-231, and 210-208 million years ago—which released significant amounts of greenhouse gases, altering ocean chemistry. The low-oxygen conditions may help explain half of Earth's Triassic extinctions.

Humans were forced to adapt to survive a supervolcano eruption 74,000 years ago

The Toba supereruption ejected 2800 cubic kilometers of ash, resulting in global cooling from blocked sunlight and acid rain. Archaeological sites show that humans developed bow-and-arrow technology to survive in arid conditions by fishing in seasonal waterholes.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

Vector-borne diseases kill more than 700,000 people globally each year—and are growing

The diseases with the greatest potential to spread widely aren't the ones that quickly kill human hosts. Instead, the best hosts or reservoirs for vector-borne diseases would be chronically ill over the long term, increasing the likelihood that the pathogen could be transmitted to others.

The Middle Ages produced inventions that still affect our lives today, like coffee houses and improved agricultural techniques.

Variola: the second-deadliest virus on Earth

Because it was declared eradicated in 1980, many forget smallpox is one of history's deadliest diseases—in its final century, it's estimated to have claimed 500 million lives. This 11-minute video from production studio Kurzgesagt takes a look at...

When exactly did Mount Vesuvius erupt in ancient Rome?

Historians used to point to the summer of 79 CE when talking about the volcano that destroyed part of ancient Rome, claiming it occurred August 24, per the sole eyewitness account. This version of Pliny the Younger's letters survived via medieval manuscripts, and other versions don't mention a date at all or give a different one: October 24. This article explores new evidence that possibly shifts the deadly disaster to that fall.

How the 1918 pandemic spurred developments in virology and vaccines

This article provides an in-depth historical account of the 1918 Spanish Flu pandemic, including its impact on the global population and how its occurrence spurred significant advancements in the study of viruses—laying the groundwork for the...

The history of germ theory, which explains that illnesses are caused by microorganisms

For centuries, the miasma theory, which held that illnesses were caused by clouds of "bad air" produced by decaying organic matter, was the accepted explanation for the spread of disease. The development of microscopes and the subsequent technology to isolate bacteria and test disease spread in mice greatly contributed to contagionists overturning miasmatists.

The deadliest aspect of volcanic eruptions is often not lava, but pyroclastic flows—avalanches of ash, gas, and rock that can move more than half the speed of sound.

A timeline of major pandemics from 1899–2025

Modern pandemics have been defined by the race between globalization (which increases risk) and the development of new medicines. The Great Influenza epidemic claimed some 50 million lives, and the COVID-19 pandemic killed more than 7 million. In between, diseases like Ebola, cholera, AIDS, and more have devastated communities.

Treating black fever can result in a complication that spreads the deadly disease

Black fever, a deadly parasitic disease second only to malaria, threatens more than 1 billion people across more than 83 countries. Also known as kala-azar or visceral leishmaniasis, the disease is caused by parasites that spread through sandfly...

Volcanic activity can lead to the formation of fertile soils

Ejected rock can introduce key minerals found in fertilizers, including iron, magnesium, and potassium, to improve soil quality. Ash and basalt crystals can be easily absorbed into soils, infusing them with sulfur, oxygen, chlorine, phosphorus, calcium, and other critical elements.

How did people survive the eruption in Pompeii?

In 79 CE, Mount Vesuvius erupted and buried Pompeii under roughly 20 feet of volcanic ash. This deadly eruption killed much of the city’s population, but archaeologists recently discovered evidence of survivors. In this podcast episode, classicist Steven Tuck challenges the popular belief of total annihilation and explains how people may have survived, and how they continued to live after the disaster.

Invasive species can harm infrastructure and threaten human health

The wildfires in Hawaii in 2022 were made worse by flammable invasive grasses introduced from Africa as livestock pasture, and Zebra mussels native to the Caspian and Black Seas have spread across Europe and the US, where they can clog power plant pipes. Invasive mosquitoes can carry diseases, such as dengue and malaria.

The word 'influenza' comes from a 15th-century Italian belief in the stars

In Renaissance Italy, epidemics were thought to result from the influence of natural disasters or celestial bodies. The illness was named "influenza", meaning “influence” in Italian.

Play 17th-century death roulette

Before modern science and medicine, death was much harder to escape. Using real mortality records from London's Dreadful Visitation–a collection of all the Bills of Mortality from 1665–this interactive game gives you an idea of what may have possibly killed you during the Great Plague. Grow your appreciation for life today as you stumble upon causes of death like “livergrown” and “drowned at St. Katharine’s by the Tower”.

When Mount Vesuvius erupted in 79 CE, it buried the Roman city of Pompeii under 20 feet of ash, which preserved it for nearly 1,700 years.

The 1957 and 1968 influenza pandemics caused millions of deaths worldwide

The 1957 H2N2 pandemic spread from East Asia, killing more than 1M globally, while the 1968 H3N2 pandemic began in Hong Kong and caused a similar toll, with both strains rapidly moving across continents.

Climate change is influencing the spread of disease

Rising temperatures and water levels are forcing animals and pathogens beyond their typical boundaries. This article and its data visualizations explore the proliferation of climate-driven diseases.

How royal panic led to Europe's deadliest witch hunts

This article delves into the witch "panics" and hunts that roiled across Scotland between 1590 and 1662. The witch hunts in Scotland were unusually deadly, with the country having five times the average European execution rate per capita. Their...

Marburg virus, related to Ebola, is also extremely deadly, and has no available vaccine.