Scientists analyzing donated wisdom teeth have created tooth organoids that can secrete essential tooth protein—an important step toward self-filling cavities or lab-grown tooth replacements.

Analysis of Maya dental sealants shows they used plant resins and gums—some derived from pine with antibacterial properties—suggesting gemstone tooth inlays may have helped reduce infection while serving ritual and symbolic purposes.

The ancient human fossil record is filled with specimens with pretty nice teeth. So why do modern humans have dental problems? Scientists can't be certain, but one hypothesis suggests the evolutionary shrinking of the human jaw crowded our mouths,...

Advancements such as 3D printing muscles, performing vaginal reconstruction with colon tissue, and growing organs in a lab have shown promise, but artificial options and transplanting substitutions continue to exhibit functional and performance limitations compared to their natural equivalents.

In November 2025, researchers studying how a brain-dead donor’s body responded to the transplantation of a genetically engineered pig kidney, published that they’ve identified immune system reactions that may explain why these pig organs get rejected. What’s more, they were able to reverse the rejections with an already available drug combination and the kidney functioned well. They also pinpointed a way to detect a potential rejection up to five days sooner.

In 2026, scientists in Slovenia developed a method to 3D print a small elephant, several microscopic geometric objects, and barcodes for cell labeling within living human cells, which continued to grow and divide thereafter. The experiment opens the door to fabricating devices within cells to study and manipulate cellular functions.

What if the thing that restored your vision… was your own tooth? That’s exactly what happened to Brent Chapman. After 20 years without sight, a bizarre surgery using his tooth as a lens restored his vision.

An organoid is a three-dimensional construct composed of multiple cell types that originate from stem cells that can simulate the architecture and functionality of native organs. One big benefit of these lab-grown organs is that drug candidates can be tested in model systems without needing live patients.

The 68-year-old New Hampshire man told USA Today that a motivator for the experimental surgery was his belief that he was going to die anyway, and other people suffering from kidney disease could gain valuable insights. Yet the surgery bought him time—he lived 271 days with a pig organ and later received a human kidney transplant. Clinical trials began in 2026 to test the pig xenotransplants in more people.

Shells for hermit crabs, wheelchairs for guinea pigs and dogs, and horseshoes for improved running performance have been created using 3D printers. Other artificial body parts made using this technology include a jaw for a loggerhead turtle, a beak for a toucan, and a tail for an American alligator.

With imaging data on a person's anatomy, external prostheses and implants, such as cranial plates or hip joints, can be custom-printed to better match a patient's body. Fabrication of porous structures can promote bone growth, leading to longer-lasting implants.

About 4,000 years ago, several goats with terrible teeth managed to outlive their better-teethed brethren. With such intense dental damage, the goats were likely fed higher-quality feed than the more dentally gifted herd members, a dietary shift that would've contributed to the difference in life span. These goat teeth underscore the hard truth that humans may inflict harm on the animals they care about most, regardless of intention.

Science writer Mary Roach speaks with journalist Terry Gross about her latest book, “Replaceable You: Adventures in Human Anatomy” and discusses topics including why pig organs have become of such interest and what religious leaders have told her about pig organs and compliance with Jewish dietary law.

Nicknamed the "unicorn of the sea," narwhals have no teeth aside from two canines that grow directly forward as tusks. For roughly 85% of females, they stay embedded in the bone. For males, they grow into large, spirally tusks that are full of nerve endings and blood vessels. Scientists today believe that tusks likely formed for sexual selection purposes and eventually evolved to assist in other processes, such as hunting.

Yale University scientists restored basic cellular activity and circulatory function in pig brains about four hours after death with a synthetic cocktail of preservatives and nutrients. This work— which didn't restart electricity activity in the brain or consciousness—could help advance future human stroke and brain injury treatments.

At companies like Ginkgo Bioworks, researchers are reprogramming cells to act as workshops that can create custom molecules, such as medicines and fertilizers, by stitching together DNA sequences—often in novel combinations—before inserting them into an organism's genome.

Using stem cells from skin and mouth cells could save hopeful parents time and money and spare egg donors from significant amounts of discomfort throughout the process. There are potential consequences, not just for infertility treatment, but for the ability to create customized cells of any type.

Somitogenesis is the process by which segmented body structures like vertebrae form in embryos. While the process is well understood in animals like mice or zebrafish it is difficult to study in humans. But now, researchers have created a model of somitogenesis, using pluripotent stem cells, called an axioloid.

Mayo Clinic transplant experts suggest that artificial intelligence could potentially improve organ donation systems in several ways, including better identifying patients most at risk for organ rejection, enhancing donor-recipient matching, and helping to avoid organ transplant needs by identifying health issues earlier.

Researchers at a hospital in the US have successfully used artificial wombs to care for preterm lambs and are now looking at the possibility of human trials. This nine-minute video includes interviews with the researchers and explains the reasoning...

In 2015, US policymakers put a halt to any government-funded work that would insert human stem cells into animals. The reasoning was that human cells might spread through the animal's body and perhaps to its brain, blurring the line between humans and nonhumans. The ban remains in place today even as gene-edited pig parts are being placed in humans.

In recent years, a number of companies have debuted meatless alternatives to traditional burgers, chicken, and more. Some are made from soy, while others use molecular formulations to recreate the flavor profile and texture of meat. Now, actual meat...

The Synthetic Human Genome Project aims to one day construct human DNA, molecule by molecule, in the hopes of creating disease-resistant cells and synthetic chromosomes for study. However, critics warn it may be misused to create enhanced or modified humans.

AI-based anatomy tools and digital cadavers are increasingly used to teach students, bypassing the ethical and consent concerns around the use of real bodies. Digital cadavers have also become less expensive than real ones, though the tactile and sensory experiences of real dissection may be irreplaceable.

Some species are used to quickly study the effects of human diseases and treatments because they are short-lived and have similar systems to those found in humans. Bacteria, like E. coli, have been used as human proxies given their rapid growth and ease of genetic manipulability.

Lab-grown meat companies promise to remove animal slaughter from the production process. But they have run into a few road bumps along the way.

Creatures like fish rely on suction to consume food, flexing their gills to create water currents that vacuum up their meals. The evolution of the tongue enabled vertebrates to completely cut ties with the sea, moving onto land where they could sample new foods and ways to eat them.

Without recourse to ancient menus, how can historians know what our ancient human ancestors—as far as 3 million years ago—ate on a daily basis? Researchers evaluate several factors, including the type of teeth the species had evolved, chemical analysis of the teeth, patterns of wear and tear on teeth, as well as food scraps found in the vicinity of ancient remains. Learn the approach to discovering ancient hominin diets.

Australian start-up Cortical Labs unveiled CL1, a hybrid chip designed to help scientists study brain function in real-time. The 800,000 lab-grown neurons on the chip are kept viable for six months via a built-in life support system.

Brain organoid research is enabling researchers to study distinct electrical firing patterns associated with schizophrenia. These "mini-brains" that are constructed in the lab from patients' cells could lead to better diagnosis approaches and drug development.

Through gene editing and the deployment of artificial cells, scientists can leverage learnings from the genetic sequencing of animals with known resistances to protect endangered species. Gene editing of certain species, such as mosquitoes, can also reduce their ability to spread diseases like malaria between humans.

In 2024, scientists developed a groundbreaking method to create diamonds at normal room temperature and pressure. This efficient and simple process contrasts with the traditional high-pressure, high-temperature method. While limitations still exist, such as minuscule sizes, this discovery moves us toward an exciting new era in diamond synthesis. Check out the article for further information about how diamonds are made.

Scientists have successfully implanted false memories in mice after studying how the editing process works in the brain. Beyond potentially deleting memories in those with PTSD, upcoming research may allow clinicians to forecast the onset of neurodegenerative diseases.