Miracle berries make things that normally taste acidic or sour, such as lemons, taste sweet, like sugar-coated candy, by binding a special protein called miraculin to your taste buds.

How bitter taste receptors help guard against infection

Receptors for "bitter" tastes evolved to detect potentially harmful plant chemicals, such as nicotine. The receptors also trigger bacteria-fighting responses, including waving hairlike projections to bat away bacteria, ordering the release of bacteria-killing nitric oxide, and calling for antimicrobial protein reinforcements.

The research that led to sour

Scientists are trying to figure out if there are unique receptors that respond to the molecules that make up flavors we associate with calcium, blood, batteries, and other items that often escape dinner menus. Taste researcher Dr. Danielle Reed says the minimum evidence for a taste category typically involves identifying dedicated receptors and then removing them to show the taste vanishes.

Umami synergy—combining glutamates and nucleotides—can amplify a meal

While glutamates are known for triggering the umami taste through specific taste receptors, nucleotides like IMP and GMP can bind alongside glutamates to enhance the receptor's response. This union explains why certain classic food combinations like bacon and eggs taste exceptionally savory.

Taste buds have evolved to fill a wide variety of functions

Taste buds do more than let you experience your favorite food. These peripheral organs can sense the chemical makeup, potential toxicity, and fleeting experience of flavor, giving the body a chance to respond to undesirable chemicals or tell the brain that you should reach for another scoop.

How fermentation enables the pickling of food and the production of beer

This process occurs when microbes produce lactic acid, ethanol, or carbon dioxide after consuming sugars. The acid helps preserve vegetables in a brine solution during pickling and gives them a sour taste, while ethanol serves as the inebriant in alcoholic beverages. The acid and carbon dioxide give sourdough bread its taste and texture.

Artificial sweeteners are considered safe for most people, but researchers are investigating their effects on gut microbiome health.

Cats have a mutation that prevents them from tasting sweetness, but goldfish are covered in taste buds and are ranked among the world's supertasters. (Paywall may apply.)

Artificial sweeteners may disrupt gut health, throwing off the balance of beneficial bacteria in the gut and shifting the composition of the microbiome.

Fake sugars may disrupt metabolic health. (Paywall may apply.)

How our sense of taste evolves as we age

Kids are hardwired to prefer sweets over greens, with sweetness a shorthand for calorie-rich and bitter flavor warning of potentially noxious plants. This holds true even in the womb, where fetuses have been seen via ultrasound scans grimacing as their hosts consume kale capsules. As they age into double digits and beyond, their taste cells and sense of smell diminish, leading to broader and less sensitive palates.

Multiple sugar substitutes were accidental discoveries when lab workers didn't wash their hands.

Aspartame was a surprise discovery from a lab working on gastric ulcers

As with saccharin and cyclamate, the aspartame discovery arose from its discoverer tasting something sweet from his workplace. In 1965, American chemist James Schlatter licked a white powder off his finger as he picked up a piece of paper and was startled to discover it tasted sweet. He applied for a patent for the substance, and received it in 1970. It is now one of the most popular artificial sweeteners. (Some users may experience a paywall.)

These cells 'taste' danger, trigger immune responses

Taste receptor-coated tuft cells are found throughout the body, where they communicate with and take part in a growing list of biological processes. In the intestines, these taste receptor-studded cells can sense byproducts of parasite metabolisms. This causes the taste receptors to release chemicals that alert the immune system, order nearby goblet cells to produce mucus, and trigger muscle contractions in attempts to launch the parasites from the intestines.

Many parts of the body, including the testicles, have bitter, sweet, and umami receptors

Taste receptors—the tiny cells that report the chemical makeup of external stimuli to the brain—in the testicles don't "taste" in the same way as the gustatory ones you use to determine if there's enough sugar in your tea. Research suggests that these "teste" receptors can sense bitter, sweet, and umami compounds and use that chemical input to control physiological processes or (literally) change direction. (Some users may experience a paywall.)

See how sugar stacks up against the sweetness of sugar alternatives, which can sometimes be hundreds of times sweeter than their sugar counterparts.

Neural replays in mice help explain food aversions

Princeton University scientists published research in 2025 analyzing how mice learn to associate certain foods or flavors with feeling ill—even when there’s a time gap between eating something and feeling sick. The work, performed with grape Kool-Aid and injections of a substance that made mice sick, traced the literal “gut reaction” of how gut distress signals are linked to neural replays of what the mouse ate.

How science came to understand umami

Before Dr. Kikunae Ikeda sat down in 1907 and pondered the taste of dashi, scientists typically agreed upon four types of taste: sweet, salty, bitter, and sour. He boiled 90 pounds of kelp into a resin that he then stripped of different compounds until he was left with a single ounce of brown crystals. Testing later revealed these crystals were glutamate, an amino acid and one of the protein's building blocks.

Sugar alcohols, a type of carbohydrate used as a sweetener, may elevate risk of heart attacks and strokes.

Artificial sweeteners aren't very helpful for weight loss.

Watermelons were once neither red nor sweet

The gargantuan summer picnic staple has a fascinating story: 100 million tons are produced worldwide and they take up the most space of any vegetable crop in the world. But not long ago, the flesh of the melon was white and it had a bitter taste.

Explaining concentrate and how concentrate-derived juice differs from its source

Developed to reduce the volume of goods—thus lowering storage and shipping costs—the concentration process uses pressure and heat to remove water, pulp, and skin from fruits. Concentrates provide significant flavor, sugar, and calories to foods in small quantities, but do not retain most of the fiber, vitamins, and other nutrients from the source fruit.

Gummy vitamins have candy-level sugar—and that sweetness is linked to overdoses

A typical gummy vitamin contains about the same amount of sugar in a single serving as one Sour Patch candy. It's linked to the increase in pediatric overdoses for products including multivitamins and melatonin. Gummy formulations also degrade quickly, so they often include much higher levels of the product in each serving than the label advertises—boosting overdose risks due to this unchecked variability. (Some users may experience a paywall.)

Xylitol, a sugar alcohol, is sometimes added to foods at 1,000 times the level seen naturally in foods

This article covers the latest research in sugar alcohols and heart health. Some work indicates that after consuming sugar alcohols erythritol or xylitol people are at an elevated risk of developing blood clots, which can cause heart attacks and strokes. Both substances occur in low levels naturally in fruits and vegetables and are also produced by the human body, but as sweeteners in foods they are present at exponentially higher levels.

A collection of molecular gastronomy techniques, from flavored air to turning oils into powder

Soy lecithin can be blended with flavored mixtures, such as herbs and Parmesan, to produce edible bubbles, which can be frozen into a solid foam. Maltodextrin can be combined with liquid fats in a food processor to create light, flavorful powders.

In June 2026, EU food safety regulators approved sales of a GLP-1-inducing food additive, a change which may lead to 'supercharged' cereals and breads in Europe within a year. (Free w/email.)

How texture affects taste

Texture is the brain's interpretation of several sensations, including pressure, as registered by our teeth, tongue, and finger tips, and sound, as recorded by our ears. Texture also speaks to food particle sizes—smaller than 35 microns contributes to the sensation of creamy—and the balance between flavor and mouth time, such as the crunch of a crispy chip or the bounce of a chewy caramel.

Breaking down various tongue disorders, from infections to genetics

Taste is one of our fundamental senses, but can be impeded by a wide variety of conditions including glossitis, angioedema, and black hairy tongue. Most are characterized by their color, shape, and sometimes change in function. Causes range from vitamin or mineral deficiencies to fluid accumulation, fungal infection, or more.

The dark side of modern sugar production

Humanity's ancestors evolved to wring more calories from sugary fruits by storing excess sugar as fat, an adaption that's culminated in many peoples' palettes preferring calorie-rich sweet. Now, the desire for sugar has both contributed to a widespread health crisis and been at the center of atrocities around the world.

Understanding the biochemistry of ingredients and taste can improve flavor and texture

Keeping eggs at room temperature produces smoother batters when baking, and doing the same with tomatoes helps prevent a mealy, granular mouthfeel. Salting meat a day before gives more time for proteins to break down, improving flavor and tenderness, while cooking vegetables in well-salted water can lock in nutrients and color.

Honeybees vomit nectar into one another's mouths to transform it into honey

Digestive enzymes break down long chains of complex sugars into simple monosaccharides, while the fanning of their wings helps honeybees evaporate water away. This process increases the acidity of the resulting honey, increasing its shelf life when sealed in beeswax.

Our love of chocolate may have to do with how it ferments than previously realized—with specific microbes associated with more fruity or acetic tastes.

Stevia has been used to treat burns and indigestion

The substance, which is roughly 300 times sweeter than sugar and scientifically known as Stevia rebaudiana, comes from a plant that grows in Paraguay and Brazil. It has long been used medicinally and as a sweetener by indigenous communities in those locations.

The ancient Romans invented the first known artificial sweetener—it involved lead. (Paywall may apply.)

Babies taste food in the womb via amniotic fluid, and it may influence future taste buds

Some estimates suggest that around Week 16 during pregnancy, a growing fetus can begin to taste amniotic fluid that contains flavors in the food that their mother consumed, due to taste bud formation. Scientists think those early flavor experiences may influence future taste preferences. Other scientific resources put that time much later, however—around Week 30.

Learn the history of food science breakthroughs from the 20th century

Long after humans developed the means to produce sufficient food to feed civilizations, scientific research focused on a wide variety of objectives, such as developing methods to preserve food quality (accomplished via frozen food), speeding up cooking (leading to the microwave), and lowering the cost of sweetening food, which high fructose corn syrup provides.