Biohacking to boost personal health has become a concept that encompasses everything from vitamin regimens and cryochambers to brain implants and red light therapy.

Biohacking: The effort to optimize health and extend life through technology

Biohacking seeks to optimize human health and performance through everything from simple lifestyle adjustments to more radical interventions like body modifications and experimental technology. At its core, biohacking covers a wide spectrum—ranging from improving sleep and focus to implanting devices that integrate technology with the human body.

What is biohacking? An overview

Biohacking is a broad collection of self-improvement techniques meant to enhance a human's health, lifespan, or ability. There are basic biohacks, like the use of caffeine, and more extreme ones, like under-the-skin implants. The difference between biohacking and standard medicine is that biohacking is primarily a do-it-yourself approach and is mostly unregulated.

My experience with biohacking

A general approach that employs technology to enhance the functioning of the human body, biohacking enthusiasts are continuously seeking new ways to optimize their performance. Martin Kremmer, an entrepreneur who became interested in the topic after experiencing burnout, explores his own experiences in biohacking his own diet and lifestyle in pursuit of a longer, healthier life.

Hacking the body for a future that didn't happen

Journalist Adi Robertson experimented with one of the most accessible biohacks: magnets. Having a tiny magnet in their right ring finger meant they could sense magnetic fields, attract small metal objects, and more. But magnets weaken over time, eroding this new sense. Such implants do more than offer a new way of interacting with the world, they also pose new complications, such as the inability to get an MRI.

Dave Asprey is considered one of the fathers of modern biohacking

Entrepreneur Dave Asprey wants to live longer than anyone else, a desire that's led him to biohacking. Asprey relies on supplements, stem cell treatments, rigid dieting, exercise, and more. The inventor of Bulletproof Coffee has no medical or nutritional training, though that's not unusual among biohacking's DIY experimenters.

Tech entrepreneur Bryan Johnson's mission to live forever

Johnson has invested millions of dollars into developing a biohacking program he believes will extend his life beyond typical expectations, relying on medical professionals to reduce his "biological age." Most notably, he drew significant public attention with reports of blood-swapping with his teenage son.

The crypto city home to biohacking experiments

The DIY nature of biohacking gives the work an entrepreneurial feel, as seen by the emergence of community labs, at-home testing kits, and corporation-backed cities that don't necessarily require government-approved testing standards. Próspera, Honduras, created by a business of the same (first) name, was born from legislation that allowed international businesses to shave off a slice of the country to establish their own micronations.

The quest to find natural ways to extend lifespan

Tales of searching for the Fountain of Youth persist. Our modern-day version is marked by promises of pharmaceutical miracles and a proliferation of viral "biohacking" routines. One doctor’s quest to unlock the keys to longevity stimulated much of this renewed fervor, though his ideas are often taken out of context.

Inside the community movement behind DIY synthetic biology

Margaret Talbot spotlights the rise of DIY biology in community labs, where amateur scientists—often outside formal institutions—create everything from insulin to prosthetic prototypes. These grassroots biohackers challenge traditional science by pursuing open, accessible innovation, raising questions about credibility, ethical oversight, and acceptance by mainstream researchers.

A comic book-style review of attending a biohacking conference

When Andrew Greenstone attended a biohacking conference in Austin, Texas, he didn't expect to walk away a newly implanted member of the techy cadre. Partway through the event, he paid $150 to have an NFC chip inserted into his right hand.

What is cancer bioengineering?

While new treatments for cancer are under continuous development, researchers are increasingly using engineering principles to find wholly new strategies to combat the disease. Directions include nanoparticle drug delivery, advanced imaging tools, developing new materials to interact with cells, tissue engineering, robotic surgeries, and more. Such interdisciplinary efforts are expected to unlock new tools and therapies beyond traditional drug formulation.

The scientist that biohacked a buff frog

If a tree frog was injected with a DNA mixture containing follistatin, a gene that may influence muscle growth, would it become buff? Josiah Zayner hopes so. By learning how to biohack animals, he hopes people are one step closer to feeling more comfortable "whipping up DIY gene therapy."

How to think yourself into health

Can the right thoughts lead to a stronger immune system? Neuroimmunologists like Hai Qi study how drugs targeting the brain, as well as thought exercises, can prompt stronger immune responses to infection. This six-minute video investigates the radical claims.

Brain implants are restoring movement and communication in early human trials

Several companies developing brain-computer interfaces have begun testing on humans with promising results. These implants have helped reanimate paralyzed limbs and enable communication, though ethical concerns remain about data privacy.

Neural interfaces offer major medical potential but raise serious ethical concerns

Although brain-computer interfaces can help people recover lost functions and allow direct brain-to-computer communication in the future, surveys have shown little public support for using them to boost abilities like memory or focus in healthy people.

The man who turned his leg into a hotspot

Biohacker Michael Laufer recently had a 512GB drive implanted in his leg, which can store data, stream music or movies, and power a hot spot and mesh network. It's called the PegLeg, and WIRED's Daniel Oberhaus spoke with Laufer about the device and the field of biohacking.

Genetic engineering will change everything forever

Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming reality. As scientists increasingly understand how specific genes cause disease, the possibility of engineering our genes to not only "fix" problems but enhance our natural ability grows.

Doctors shift focus from extending lifespan to lengthening health span

As scientific advances extend the average human lifespan, many are turning their attention toward extending "health span." Health span refers to the number of years one is active and disease-free. The ultimate goal is to extend one’s health span to match one’s lifespan.

Health span: The number of years one is active and disease-free

As scientific advances continue to extend the average human lifespan, many are now turning their attention toward extending "health span." The ultimate goal would be to extend one's health span to match one's lifespan, which would necessitate a shift in focus toward the pursuit of healthy aging. (Some users may experience a paywall.)

Precision medicine, offering the right treatment at the right time for individuals, integrates genomics, data analytics, and AI to predict risks, personalize treatments, and improve patient outcomes.

An essay exploring how living day-to-day with a brain implant helps restore a sense of identity

Companies like Neuralink are experimenting with volunteers who have lost control over their bodies. Many of the program's participants claim the most significant benefit from the tool is the ability to perform simple, mundane tasks, such as playing video games or shaking hands, rather than more obvious milestones like walking or eating. This essay explores what it's like, day to day, to use a brain implant.

Is synbio really cool, really scary, or both?

There's always been a divide between technology, the inanimate stuff that we build, and biology, the living stuff that nature builds. Synthetic biologists are trying to figure out how to close the gap by building living things.

Multiple new research paths may lead to slowing (or even reversing) aging

Aging has always been inevitable, but fasting, epigenetic reprogramming, and parabiosis seem to help people stay young. By studying centenarians, memory, and even the humble roundworm, scientists are looking for the genetic basis to live not just a long life, but a healthy one.

Moving your body every day is key to longevity

In an era of biohacking, where millionaires subject themselves to draconian routines and tests to de-age themselves, one study suggests a super simple key predictor of mortality: more than any other trait, how much subjects moved determined how long they'd live. Movement mattered even more than age in predicting overall life longevity. Researchers suggest this means we should all simply get outside a bit more. Read more about the study here.

Inside entrepreneur Bryan Johnson's race to live forever

Created by entrepreneur Bryan Johnson in 2022, the Rejuvenation Olympics asks participants to find ways, including exercise and dietary supplements, to slow their biological aging. But some of these tactics are extreme in cost or nature—such as Johnson's regular injections of blood from his teenage son.

The origin of cyborgs

The term "cyborg" was coined in a 1960 academic paper discussing what alterations humans would need to undergo to survive in extraterrestrial environments, a venture far "more logical than providing an earthly environment" in space. According to authors Manfred E. Clynes and Nathan S. Kline, Cyborgs with a capital C have incorporated exogenous components that extend their ability to adapt to new environments. Read the paper here.

On average, the human body produces about 100 watts of electricity—enough to power a light bulb—but some people can produce over 2,000 watts in short bursts, such as when sprinting.

Activity trackers promise to improve health by forcing us to examine the facts

Explore how modern fitness culture, rooted in capitalist ideals of productivity and control, shapes our perception of health and self-worth. The author blends cultural criticism with personal insight to examine the contradictions of the wellness industry, the rise of wearable tech, and what it means to "optimize" a body.

Using brain implants to restore vision

Several companies are attempting to create brain-computer interfaces that skip over retinas and optic nerves to allow visual input to go straight to the brain, potentially restoring some sight to the blind. Clinical trial findings suggest restored sight is sparse and manifests differently than a sighted person might expect, appearing as specks of "light" clusters called phosphenes to help differentiate one's surroundings.

This scientist treated her own cancer

Virologist Beata Halassy treated her own breast cancer by injecting the tumor with lab-grown viruses. Though this self-treatment worked, it has not been approved for widespread use. Read to learn more about her fascinating experience, and how it has led to conversations about safety and ethics.

'Endoevolution' refers to the Darwinian selection happening continually inside us

The term, coined by Roxanne Khamsi in her 2026 book "Beyond Inheritance: Our Ever-Mutating Cells and a New Understanding of Health" describes the idea that evolution does not just occur across generations of humans. Instead, mutated cells continuously compete with healthy ones in our bodies, with implications for our tissues and health. Khamsi says these autocorrections are essentially natural gene therapy. 

Biotech is trying to boost drug production efficiency—using chicken eggs

A company called Neion Bio is genetically engineering birds in a bid to produce medical compounds, a herculean task that scientists have struggled with for decades. The US FDA has approved only one chicken-derived drug in the past—an expensive treatment for a rare liver disorder. (Some users may encounter a paywall.)

Neural implants blur the line between personal intention and machine execution

A key ethical dilemma—the contemplation conundrum—explores whether implants might misinterpret mere imagination as intent to act. Neuroscientists have found no brain signal that clearly marks when someone decides to act, making intent hard to detect in neurotechnological systems.

Can humans delay or reverse old age?

We're not sure yet. Researchers at the University of California San Francisco are studying why some conditions and behaviors, such as low-oxygen environments and exercise, benefit the aging process, hoping to reveal potential health applications. Some of this research focuses on klotho, a naturally occurring age-regulating hormone named after the Greek Fate Clotho. Animal studies on klotho brain injections found subjects had improved memory recall and age-related degeneration resistance.

Synthetic biology transforms cells into custom DNA foundries

At companies like Ginkgo Bioworks, researchers are reprogramming cells to act as workshops that can create custom molecules, such as medicines and fertilizers, by stitching together DNA sequences—often in novel combinations—before inserting them into an organism's genome.

Brain-computer interfaces create a direct link between the brain and external devices

The technology enables users to control prosthetics, computers, or even games using only their thoughts. In 2021, a monkey played table tennis using only its brain, thanks to a Neuralink device, marking a major milestone before human trials began in 2024.

Interest in intermittent fasting outpaces the science

The public interest in fasting diets has outpaced the science behind related health claims. This article details how the science of fasting diets is mainly exploratory and focused on longevity and disease prevention. Current findings suggest fasting kick-starts regenerative processes in the body, decreases inflammation, and improves health outcomes overall. However, much of this research focuses on the short-term impact of fasting.

Aging is a complex biological process affecting our cells, tissues, and organs.

The US FDA issued a 2025 warning about BPC-157 and other popular peptides that are marketed for various regenerative properties.

Open brain surgery is not required for BCIs inserted via blood vessel injection

Synchron's brain-computer interface, the Synchron Switch, takes advantage of preexisting medical devices, such as stents and catheters. Cells grow over the device over a 90-day period, incorporating it into the vessel wall and minimizing clots.

Exercise improves brain blood flow, stimulates neural growth, and more

Exercise has dramatic effects on human biology, including reducing some of the long-term harms associated with chronic stress. Its effects are also pronounced in the brain, including improved memory retention, sleep, cognitive functioning, and more.

Stem cells can reboot the ability of cells to repair themselves

Stem cells—special cells that can self-renew and evolve into new cell types—may provide a path to address aging. Instead of repairing aging cells, stem cells can replace a cell's "repair kit," effectively rebooting the internal processes of tissues to a more youthful state.

CRISPR is a gene-editing tool that lets scientists cut out and replace damaged DNA

One of the most significant advances in modern medical science, CRISPR is a molecular tool for making precise changes to a gene's DNA. The technology has already been approved for treating sickle-cell disease.

The strange endurance of consuming blood for health

Blood's importance to humanity is best summarized this way: without it, we die. This importance naturally begets assumptions about its medicinal properties, many of which appear accessible through drinking or eating the fluid connective tissue. This article details the history of blood drinking, from ancient Roman gladiators to modern-day sanguinarians.

An overview of bioremediation, which can help clean up oil spills, mining waste, and some plastics

The umbrella term refers to a variety of techniques that use organisms to remove harmful substances from an environment or break them down into nontoxic compounds. Because the availability of certain resources can limit the growth of these organisms and impair bioremediation efforts, nutrients such as fertilizers can be deployed to accelerate cleanup.

How art helps us process our feelings

The internet is chock full of hacks and apps that supposedly help you optimize yourself into a more productive person. But Aparna Chivukula argues that spending so much mental energy on "wellness" misses a larger philosophical issue, one that can only be explored through art.

Why don't humans hibernate?

Hibernation is a superpower in the animal world that allows certain species to time travel from difficult times to abundance. This essay in Aeon explains this helpful natural process and why humanity's technological advancements may have hindered our ability to participate in the practice. Learn about the rising interest in human hibernation as a result of modern adversity, and if it could potentially become a reality.

Learn about historical uses of bioremediation, the oldest cleanup method on Earth

Biochemical reactions that decompose complex molecules into simpler ones have occurred on Earth for as long as life has existed and have gradually transformed the planet into a celestial body that is increasingly habitable to greater biodiversity. Along the way, modern, human-made bioremediation techniques began to take shape in Santa Maria, California, in the 1960s.

Humans need vitamins, but research is mixed on taking supplements

When an organism needs an organic molecule to survive, but cannot synthesize enough of it itself, that molecule is called a vitamin. Typically, we consume vitamins through food, but many resort to supplements—a common and mostly unregulated practice.

One biologist is leading the blue zone criticisms—both questioning the original recordkeeping for these purported longevity-prone locations and pointing to recent research showing declining numbers of healthy seniors in several official blue zone regions.