The crypto city home to biohacking experiments

Biohacking to boost personal health has become a concept that encompasses everything from vitamin regimens and cryochambers to brain implants and red light therapy.

My experience with biohacking

A general approach that employs technology to enhance the functioning of the human body, biohacking enthusiasts are continuously seeking new ways to optimize their performance. Martin Kremmer, an entrepreneur who became interested in the topic after experiencing burnout, explores his own experiences in biohacking his own diet and lifestyle in pursuit of a longer, healthier life.

Inside the community movement behind DIY synthetic biology

Margaret Talbot spotlights the rise of DIY biology in community labs, where amateur scientists—often outside formal institutions—create everything from insulin to prosthetic prototypes. These grassroots biohackers challenge traditional science by pursuing open, accessible innovation, raising questions about credibility, ethical oversight, and acceptance by mainstream researchers.

Biohacking: The effort to optimize health and extend life through technology

Biohacking seeks to optimize human health and performance through everything from simple lifestyle adjustments to more radical interventions like body modifications and experimental technology. At its core, biohacking covers a wide spectrum—ranging from improving sleep and focus to implanting devices that integrate technology with the human body.

What is biohacking? An overview

Biohacking is a broad collection of self-improvement techniques meant to enhance a human's health, lifespan, or ability. There are basic biohacks, like the use of caffeine, and more extreme ones, like under-the-skin implants. The difference between biohacking and standard medicine is that biohacking is primarily a do-it-yourself approach and is mostly unregulated.

Tech entrepreneur Bryan Johnson's mission to live forever

Johnson has invested millions of dollars into developing a biohacking program he believes will extend his life beyond typical expectations, relying on medical professionals to reduce his "biological age." Most notably, he drew significant public attention with reports of blood-swapping with his teenage son.

Dave Asprey is considered one of the fathers of modern biohacking

Entrepreneur Dave Asprey wants to live longer than anyone else, a desire that's led him to biohacking. Asprey relies on supplements, stem cell treatments, rigid dieting, exercise, and more. The inventor of Bulletproof Coffee has no medical or nutritional training, though that's not unusual among biohacking's DIY experimenters.

A comic book-style review of attending a biohacking conference

When Andrew Greenstone attended a biohacking conference in Austin, Texas, he didn't expect to walk away a newly implanted member of the techy cadre. Partway through the event, he paid $150 to have an NFC chip inserted into his right hand.

Hacking the body for a future that didn't happen

Journalist Adi Robertson experimented with one of the most accessible biohacks: magnets. Having a tiny magnet in their right ring finger meant they could sense magnetic fields, attract small metal objects, and more. But magnets weaken over time, eroding this new sense. Such implants do more than offer a new way of interacting with the world, they also pose new complications, such as the inability to get an MRI.

Synthetic biology transforms cells into custom DNA foundries

At companies like Ginkgo Bioworks, researchers are reprogramming cells to act as workshops that can create custom molecules, such as medicines and fertilizers, by stitching together DNA sequences—often in novel combinations—before inserting them into an organism's genome.

How to prevent a worst-case scenario with synbio

Author and entrepreneur Rob Reid reviews the risks of a world where more and more people have access to the technology needed to create a doomsday bug that could wipe out humanity.

The scientist that biohacked a buff frog

If a tree frog was injected with a DNA mixture containing follistatin, a gene that may influence muscle growth, would it become buff? Josiah Zayner hopes so. By learning how to biohack animals, he hopes people are one step closer to feeling more comfortable "whipping up DIY gene therapy."

Shenzhen, China is known as the 'Silicon Valley of Hardware'

The "Silicon Valley of Hardware" is a major manufacturing hub. This WIRED documentary from 2016 does a deep dive into how this Chinese city's practice of copycat manufacturing alongside its innovative culture has made it China's own Silicon Valley.

Listen to a podcast that explains why Elon Musk is creating a 'company town' in Texas

Elon Musk is recreating an old tradition of large corporations creating "company towns" where their workers can live. In his case, the town, which he is calling "Snailbrook," is being created for SpaceX and some of his other companies in Bastrop, Texas, a small community roughly 45 minutes outside of Austin.

The man who turned his leg into a hotspot

Biohacker Michael Laufer recently had a 512GB drive implanted in his leg, which can store data, stream music or movies, and power a hot spot and mesh network. It's called the PegLeg, and WIRED's Daniel Oberhaus spoke with Laufer about the device and the field of biohacking.

Is synbio really cool, really scary, or both?

There's always been a divide between technology, the inanimate stuff that we build, and biology, the living stuff that nature builds. Synthetic biologists are trying to figure out how to close the gap by building living things.

The world's first commercial biological computer combines neurons with silicon

Australian start-up Cortical Labs unveiled CL1, a hybrid chip designed to help scientists study brain function in real-time. The 800,000 lab-grown neurons on the chip are kept viable for six months via a built-in life support system.

Inside entrepreneur Bryan Johnson's race to live forever

Created by entrepreneur Bryan Johnson in 2022, the Rejuvenation Olympics asks participants to find ways, including exercise and dietary supplements, to slow their biological aging. But some of these tactics are extreme in cost or nature—such as Johnson's regular injections of blood from his teenage son.

The origin of cyborgs

The term "cyborg" was coined in a 1960 academic paper discussing what alterations humans would need to undergo to survive in extraterrestrial environments, a venture far "more logical than providing an earthly environment" in space. According to authors Manfred E. Clynes and Nathan S. Kline, Cyborgs with a capital C have incorporated exogenous components that extend their ability to adapt to new environments. Read the paper here.

The quest to find natural ways to extend lifespan

Tales of searching for the Fountain of Youth persist. Our modern-day version is marked by promises of pharmaceutical miracles and a proliferation of viral "biohacking" routines. One doctor’s quest to unlock the keys to longevity stimulated much of this renewed fervor, though his ideas are often taken out of context.

Silicon Valley startups Orchid, Nucleus, and Genomic Prediction are selling so-called polygenic tests for prospective parents

These tests claim to show how at-risk a hypothetical baby would be for genetic syndromes. The newfound industry has prompted ethical and medical debates, with critics questioning their accuracy and highlighting the potential problems behind pursuing the perfect baby.

Your iPhone started with a Cold War secret

Silicon Valley wasn't supposed to happen. A stretch of California orchard land somehow became the place that built the modern world: chips, PCs, the internet, the smartphone, and now AI. But the real story isn't the garage myth. It's a series of contradictions hiding in plain sight.

Billionaires are racing to space to control future markets

Although different companies have described focuses ranging from luxury tourism to Martian space colonies, all are building infrastructure to capitalize on the shift away from government-only control and betting big on reusability and scale. By securing public contracts and subsidies, they aim to develop strategic partnerships toward dominance in low Earth orbit.

Singapore, one of the world's smartest cities

A fascinating look into what makes Singapore one of the smartest cities in the world, including human-centric innovations benefitting human health such as the AI-powered "Smart Elderly Alert System."

Biotech is trying to boost drug production efficiency—using chicken eggs

A company called Neion Bio is genetically engineering birds in a bid to produce medical compounds, a herculean task that scientists have struggled with for decades. The US FDA has approved only one chicken-derived drug in the past—an expensive treatment for a rare liver disorder. (Some users may encounter a paywall.)

Venture firm a16z's crypto canon

Andreessen Horowitz (a16z) is a leading venture capital firm with deep expertise in cryptocurrency and blockchain technology. For 10 years, the firm has built its internal knowledge in the area, and archived a wide range of explainers exploring everything from fundamentals to emerging crypto trends, and much more.

What its like to live in the world’s ‘smartest cities’

What’s it like to live in a smart city? The BBC interviewed residents of five of the world’s smartest, as determined by the International Institute for Management Development, to find out. (See previous resource for those rankings.) Common praises included ease of transportation, sustainability initiatives and proximity to nature.

An essay exploring how living day-to-day with a brain implant helps restore a sense of identity

Companies like Neuralink are experimenting with volunteers who have lost control over their bodies. Many of the program's participants claim the most significant benefit from the tool is the ability to perform simple, mundane tasks, such as playing video games or shaking hands, rather than more obvious milestones like walking or eating. This essay explores what it's like, day to day, to use a brain implant.

The FBI once raided Polymarket CEO Shayne Coplan's home

In 2024, after Polymarket markets favored what turned out to be the winning outcome of the US presidential election, agents raided Coplan's New York City apartment. Coplan, who was only 26 years old at the time, was home during the raid and turned over his devices to authorities.

The $3B project scientists called 'junk'

In 1990, scientists set out to map all of human DNA. A $3B bet many called "junk." But the Human Genome Project's radical transparency and a race with a private company sped it to completion in just 13 years. Today, that once-contested map underpins nearly every breakthrough in genetics and personalized medicine.

Read a book making the case for 'smart enough' cities

University of Michigan professor Ben Green argues that cities should be enhanced by technology rather than driven by it, thereby preventing injustice and inequality beneath their surface. By embracing social change in conjunction with smart technologies, residents, Green suggests, can avoid valuing such technologies as ends in themselves.

Woven City at the base of Mount Fuji in Japan

The Woven City at the base of Mount Fuji in Japan is a ‘living laboratory’ for new technologies. It is being developed by Toyota subsidiary, Woven Planet, and will be the world’s first programmable city.

Tech giants like SpaceX and Meta are increasingly behaving like sovereign powers

Companies now make unilateral decisions once reserved for nation-states, such as controlling satellite internet access in active war zones and influencing global information flows. Lawmakers and the international order are struggling to keep up with technological developments, let alone regulate them.

Y Combinator changed the way startups around the world are built

Many of the philosophies that the leaders of Y Combinator have infused into the program’s portfolio companies have become the playbook for building the next big thing, such as its focus on founder personality and more.

Implanted neurotechnology can leave users vulnerable when manufacturers go under

Despite providing relief from neurological conditions, patients are left stranded when the companies that make these devices shut down. The lack of regulation means patients often face technical failure, insurance battles, or risky surgeries to maintain their quality of life.

China is producing many peptides or peptide components sold in the US.

Bluesky is gaining momentum by offering users full control over their experience

Controversial changes made by Elon Musk to X have inspired an exodus from that platform and growth in Bluesky. The latter's open-source model gives users customizable feeds, portability between services, and a "billionaire-proof" design that prevents corporate takeover.

Many startups now have shoes-off policies

This website keeps track of startups with "no-shoes" offices so you can browse a list of barefoot companies—plus, see which of them are hiring.

In 2025, researchers in the UK began working on developing artificial DNA

The Synthetic Human Genome Project aims to one day construct human DNA, molecule by molecule, in the hopes of creating disease-resistant cells and synthetic chromosomes for study. However, critics warn it may be misused to create enhanced or modified humans.

Steve Bannon was made CEO of the company in charge of Biosphere 2 in 1994

After providing $200M to launch and upgrade B2 before its second mission, billionaire philanthropist Ed Bass appointed the future political strategist and then financial consultant to help find new investments and bring costs under control. Fearing interference from non-science experts, Biospherians from the first mission vandalized the project.

A visual guide to Hollywood dystopias and their real-world locations

Even the most dire dystopias are grounded in the real world. That's especially true with dystopian movies, which turn real cities into near-future nightmares. This guide from Atlas Obscura takes readers on a tour through some of the most recognizable, from "Blade Runner" (filmed in Los Angeles) to "Total Recall" (Mexico City, Mexico), "The Matrix" (Sydney, Australia), and more.

Ethereum Founder Vitalik Buterin was surprised by the emergence of NFTs

Scams have pervaded the NFT space and made critics question their legitimacy, but proponents believe their use cases could one day extend to real estate and credit scores.

One biologist is leading the blue zone criticisms—both questioning the original recordkeeping for these purported longevity-prone locations and pointing to recent research showing declining numbers of healthy seniors in several official blue zone regions.

Anthropic's Frontier Red Team assesses the dangers of its AI tools through 'evals'—safety tests that probe models to disclose sensitive information.

WellHub is a startup serving roughly 4 million people in 11 countries, providing broad wellness benefits to employees

Valued at $2.4B in 2025, the company helps workers get gym access and meditation apps, in addition to basic healthcare. Listen to the founder of the company, Cesar Cevalho, explain how he scaled the company with Jeff Berman.

Meet six commercially available synbio products

An article exploring the science behind synbio products currently on the market, and projecting the products that can be expected over the next 10 years.

Stephen Findeisen is the YouTuber taking on crypto scams

While many cryptocurrencies are focused on advanced technical projects or real-life uses, the proliferation of easy-to-create memecoins has led to a boom in scams. Stephen Findeisen, aka Coffeezilla, is regarded as one of the best independent investigative journalists exposing high-profile frauds, pump-and-dump schemes, rug-pulls, and more.

Despite privacy risks, scientists are using DNA in the air to assess ecosystem health

While DNA in soil and water samples has long been used for such analyses, airborne DNA is being incorporated into such efforts to monitor individual species abundance, detect invasive species, measure biodiversity, and determine the success of conservation actions. Future work may include detecting attacks from biological weapons.

Contestants in an annual extreme sports competition are encouraged to use steroids and growth hormone, using athletes as guinea pigs.

Bioluminescence may provide a sustainable alternative to electric lighting

French start-up Glowee is experimenting with lights made from bioluminescent microorganisms in public spaces to reduce energy use. While the technology shows promise, challenges remain with brightness, maintenance, and scaling it for widespread use.