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A number of psychedelics will be fast-tracked for research into their potential to treat serious mental health issues following an executive order signed by President Donald Trump Saturday.
Many such compounds (including LSD, psilocybin, and more) are classified as Schedule I drugs—illegal to possess and federally regarded as having no medical use. Researchers say the restrictions create significant hurdles for formal clinical trials, despite some evidence they may help treat a range of disorders.
The order also earmarks $50M for state-level research into ibogaine (pronounced “e-BOW-gain”). The plant-based psychoactive compound is associated with intense episodes and has been linked to cardiac issues but has also proved effective in small studies to alleviate substance use disorders and reduce PTSD symptoms. The order, reportedly prompted by a text message to the president from podcaster Joe Rogan, does not reclassify any of the compounds.
Listen to veterans discuss their different experiences with psychedelics here.
PS—If you're interested in this story, check out our weekly 1440 Health & Medicine newsletter. Each week, we explore the science and history of a wide range of topics (this week, we look at in vitro fertilization). Join 135,000+ readers here! |
The US says it has seized an Iranian ship in the Strait of Hormuz—an almost 900-foot cargo vessel that allegedly refused the US' warnings to stop. The claim comes days before the countries' two-week ceasefire expires Wednesday. See US footage of the ship here.
The US says it has turned away more than 20 ships in the strait, part of its weeklong naval blockade on ships entering or exiting Iranian ports. Control over the strait, through which 20% of the world's oil typically passes, has been a primary sticking point in US-Iran negotiations. Average gas prices in the US may not fall below $3 per gallon again until next year, the US energy secretary has warned. See a live map of ships in the strait here.
Meanwhile, US negotiators head to Islamabad, Pakistan, today to resume peace talks. Iran has not confirmed it will send representatives as of this writing, though reports suggest Iran's delegation will arrive tomorrow. |
Hundreds of animal rights activists at a dog-research facility in Wisconsin, including some attempting to break into the facility, were met with rubber bullets and pepper spray Saturday. Dozens of people were arrested.
Ridglan Farms is a beagle-breeding and research lab located 25 miles southwest of Madison. Last year, a special prosecutor found one of the company's experiments likely involved criminal conduct (employees testified dogs had been subjected to surgeries without general anesthesia). The company, which owns roughly 2,000 dogs, has denied wrongdoing but agreed to give up its breeding license July 1.
In the meantime, a local animal rights group has sought to purchase the dogs for $1M. Last month, the group broke in and removed 22 dogs. Over the weekend, the group again met at Ridglan Farms with avowed plans to break in and release more dogs. One person drove a pickup truck through the front gate, according to police. See footage and interviews with protesters here (via YouTube). |
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It's easy to forget that our sweat isn't just water. But why is it that we only down a glass of water after a long run or a hot day? Our sweat consists of water and salt, so next time you reach for that glass of water ... remember to replenish electrolytes, too.
After years of mixing his homemade electrolyte blends and frustration with the lack of healthy options on the market, LMNT Co-founder Robb Wolf used his experience as a biochemist and Navy SEAL resiliency committee member to create his own product. With no sugar, artificial ingredients, or junk found in conventional sports drinks, LMNT is your chance for a clean electrolyte boost after a long day or intense workout. For the in-between moments, LMNT’s new 12oz Sparkling delivers the same electrolyte ratio in a lighter dilution, perfect for the workday, the weekend, and every sip in between.
Hydrate your body the right way. Enjoy a FREE sample pack of 8 flavors with any purchase, plus a money-back satisfaction guarantee. |
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Sports, Entertainment, & Culture |
> Coachella 2026 wraps its second weekend with headlining sets from Justin Bieber, Karol G; Madonna appears alongside Sabrina Carpenter, among highlights (More) | What is Coachella? (More) |
> Roman Reigns defeats CM Punk to win WWE World Heavyweight Championship at WrestleMania 42 (More) | NBA playoffs tip off; see schedule and bracket (More) | 2026 Stanley Cup playoffs also tip off; see schedule and bracket (More) |
> Oklahoma wins NCAA women's gymnastics championship for fourth title in five years (More) | See highlights from the all-around winner (More via YouTube) |
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> Humanoid robot surpasses human half-marathon world record by roughly seven minutes in Beijing event meant to demonstrate advances in the technology (More) | Others fall over at the starting line, need stretcher (More, w/video) |
> Cygnus X-1 black hole jets—matter violently ejected from the poles of black holes—have the power equivalent of 10,000 suns, first direct measurement finds (More) | Want to learn the science behind black holes (and much more)? Sign up for our weekly 1440 Science & Tech newsletter (More) |
> New "immune priming" therapy allows some patients to receive liver transplants without relying on immunosuppressant drugs, keeping the body from rejecting the new organ (More) |
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Is the Future of Weight Loss Microdosing? |
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> US stock markets rally Friday (S&P 500 +1.2%, Dow +1.8%, Nasdaq +1.5%) following preliminary news the Strait of Hormuz was "fully open" (More) |
> Meta targets May 20 to lay off around 8,000 employees, or 10% of its workforce, according to reports; company expects further cuts in the second half of 2026 (More) | Everything we learned researching Mark Zuckerberg (More) |
> Autonomous vehicle startups raised $21.4B across 34 deals globally through April 15, more than 2.5 times funding from all of 2025 (More) | AI coding startup Cursor in talks to raise $2B at a $50B valuation, with round led by a16z and Thrive (More) |
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> Gunman kills seven of his children and one other child in Shreveport, Louisiana, in what police characterize as a domestic incident (More) | Shooting near University of Iowa leaves five people wounded, including three students (More) |
> Video footage shows DC police visiting the home of Rep. Cory Mills (R, FL-7) in February 2025 over alleged assault of 27-year-old woman, per Washington Post (More) |
> UK authorities arrest suspects in wave of arson attacks on Jewish synagogues, Iranian opposition outlet; no one has been wounded as of this writing (More) |
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The Truth About Sodium & Peak Performance |
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LMNT was born from a growing body of research revealing that optimal health outcomes occur at sodium levels 2-3x government recommendations. (We’re not talking table salt.) Each LMNT serving delivers a science-backed electrolyte ratio without the sugar, fillers, or artificial coloring found in traditional sports drinks. And now they come in 12-oz sparkling cans, too!
From everyday athletes to the US Olympic Weightlifting team, and 100s of the world’s leading health and fitness experts, top performers trust LMNT. Enjoy a FREE sample pack of all 8 LMNT flavors, plus a risk-free refund policy. |
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Historybook: "Dracula" author Bram Stoker dies (1912); "Star Trek" actor George Takei born (1937); Columbine High School massacre kills 12 students and one teacher (1999); Danica Patrick becomes the first woman to win an IndyCar Series race, watch here (2008)
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1Disclosure: Noom Microdose GLP-1Rx Program involves healthy diet, exercise, medication (when appropriate) and support. Individual results vary. Medications based on personal need as determined by third-party clinician. Not reviewed by FDA for safety, efficacy, or quality. No affiliation with Novo Nordisk Inc., the only US source of FDA-approved semaglutide. Not available in all 50 US states. Initial 4 week subscription from $79 plus tax and $199 per month plus tax for 12 week subscription thereafter. New pricing for new accounts only effective as of March 31, 2026. |
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