'Science and everyday life cannot and should not be separated. Science, for me, gives a partial explanation of life.' - Chemist and X-ray crystallographer Rosalind Franklin (1920 - 1958)

While remembered for her critical but under-credited role in uncovering parameters for the structure of DNA, Rosalind Franklin made significant contributions across coal chemistry and virus structure. Her research helped improve fuel efficiency, wartime protective equipment, and foundational knowledge in molecular biology.

Her X-ray diffraction imaging helped uncover the structure of DNA, which earned James Watson, Francis Crick, and Maurice Wilkins a Nobel Prize. The same techniques enabled virus imaging, contributing to Aaron Klug's Nobel Prize in chemistry.

Rosalind Franklin captured “Photo 51,” the key to DNA’s double helix. Her data, shared without her knowledge, helped Watson and Crick win a Nobel. She never got the prize, but today, her role in unlocking life’s blueprint is finally recognized.

Particularly at the frontiers, investigations conducted based on established knowledge can provide unexpected results. This opens the door to revising existing models, inspiring new lines of research, and ultimately leading to better future comprehension. For instance, experiments on the speed of light and the expansion of the universe yielded then-confusing data that led to revolutionary insights.

Although unpublished, the data reached James Watson and Francis Crick, who worked at another institution. Incorporating her data allowed them to validate their model of DNA, which they published without crediting her.

Through the acquisition of scientific knowledge, scientists construct explanations of the world, which are rigorously tested and verified until they narrow down to a leading theory of the natural world. However, because of how science works, these ideas will never become factual, as they must always remain open to be iteratively revision based on new data.

"The scientific man does not aim at an immediate result ... His duty is to lay the foundation for those who are to come, and point the way."

-Frances Perkins (1880-1965), first female member of US Cabinet

Cutting-edge microscopy has revealed previously unseen interactions of biological molecules within their cellular environment, enabling scientists to observe and analyze the molecules in a holistic view. This podcast explains the minute advancements made over the last few decades in observing cells, revealing how scientists have come and what the future holds for the field.

Despite working together to win the Nobel Prize for their discovery of the structure of DNA, Francis Crick and Maurice Wilkins objected to the publication of James Watson's account of DNA's discovery. Those involved describe how he villainized Rosalind Franklin and downplayed her work.

Is the universe made up of a continuous substance, or a finite amount of tiny, indivisible atoms? The atomic hypothesis, largely vindicated in the 20th century, was forgotten for nearly 2,000 years after first being formulated by the Greek philosopher Democritus. Learn more about the theory and its implications for science and human life with this reflective essay.

- Marine biologist and environmentalist Rachel Carson (1907-1964)

To capture the X-ray diffraction image of DNA from the thymus of a calf, Franklin built a humidity-controlling camera to isolate the B form of DNA. The exposure lasted 60 hours and produced a cross pattern, indicating a helical structure.

Facts are observations of the world, and they can be pooled together for a given phenomenon to develop a hypothesis—a proposed explanation consistent with observations that requires further investigation. Experiments and additional data can rule out many hypotheses or graduate a proposed explanation into a widely accepted and validated theory.

Scientific laws describe outcomes of specific conditions, and scientific theories explain why those outcomes occur. Both are supported by observational and experimental data and can each inform one another, but neither can become the other. Instead, additional data can improve each towards more accurate descriptions and explanations of reality.

- Albert Einstein

Life can only arise in incredibly specific conditions, an abundance of certain substances like water and phosphorus, lots of time, and the right proximity to a heat-and-light-providing star. These two experts on evolution of life say above all, life requires luck. Here's a list of eight ingredients to life.

"If I could remember the name of all these particles, I'd be a botanist."

Brian Cox, Royal Society Professor for Public Engagement in Science, discusses the fundamental principles of quantum mechanics, emphasizing their importance in understanding the nature of reality and their practical applications in emerging technologies like quantum computers.

- Mae Jemison (1956-present), the first Black woman in space

Franklin's work revealed the role of ribonucleic acid in virus infectivity, contributing to a foundational understanding of genetics and virology. Her molecular model of the virus was featured as the centerpiece at the 1958 Brussels World's Fair.

- Isaac Asimov

Papers by Watson and Crick, Wilkins, and Franklin were fast-tracked without peer review, and their order was arranged between lab heads and editors. Franklin's appeared last, making her paper read as though supporting Watson and Crick—because they'd already incorporated her data before it was published.

Those involved in the predecessor of the modern scientific discipline engaged in experimentation to develop recipes that would transform ordinary matter into gold and to create medicines, cosmetics, dyes, and alloys. Over the course of centuries, scientists identified unique elements, organized them based on their properties in the periodic table, and eventually developed the technology to discover the internal structure of atoms.

- Science fiction writer Ray Bradbury

After confirming that the accuracy of some laws of physics is limited to certain domains, science became more hesitant to categorize identified mathematical relationships, such as quantum mechanics, as unchanging laws. Instead, these recent, complex frameworks are designated as theories to acknowledge that they are conditional and may be part of a larger, more complete future framework.

Rosalind Franklin and Raymond Gosling captured the photo after bombarding DNA fibers with X-rays and observing how the beams were deflected. The photo had a 62-hour exposure time and indicated a helical structure for DNA.

- Author Malcolm Gladwell (1963 - present)

On its own, no study serves as a source of truth or solves an existing problem indefinitely, though many can be analyzed collectively in a systematic review to build more confidence—the result of more data—in a conclusion. Studies can explore knowledge gaps or test an existing theory, which is always subject to refinement and improvement.

- Jackie Robinson, the first Black MLB player (1919-1972)

- President Franklin D. Roosevelt (1882–1945)

-Poet Robert Frost (1874-1963)

Erwin Schrödinger's famous cat thought experiment illustrates how quantum objects can exist simultaneously in multiple states. This superposition allows electrons to behave as particles and waves, enabling chemical bonds and the function of modern electronics.

When you close your eyes, do you see static or colorful patterns or an "intrinsic grey" known as Eigengrau in German? This variation of our internal experiences is just the tip of the iceberg, one that scientists are increasingly studying and...

Popularized by Aristotle in the 4th century BCE, spontaneous generation was used to explain phenomena like mice appearing in seemingly sealed grain storage. The invention of the compound microscope in the late 16th century led to the identification of cells as the basic unit of life, but it was not until 1855 that their origin from preexisting cells was established.

-Alexander Graham Bell (1847-1922)

- Radio inventor Guglielmo Marconi

One of the most profound mysteries of human life on earth is the presence of living cells: organic, self-organizing, reproducing creatures with a drive to survive within given set conditions. Traditional theories posit life came from divine...

- Actress Agnes Moorehead (1900–1974)

Nature is full of symmetries, from spiral galaxies to florets of broccoli. So why do complex creatures break the pattern?This short video discusses why symmetry came to dominate life on Earth, and how many complex life forms, such as humans, transitioned from radial to lateral symmetry.

There's always been a divide between technology, the inanimate stuff that we build, and biology, the living stuff that nature builds. Synthetic biologists are trying to figure out how to close the gap by building living things.