Seized as Infants

The four healthy girls were delivered by cesarean section and joined a larger family that includes their parents and a 2-year-old older brother. Without the use of fertility drugs, quadruplet births are rare, but the chances are even slimmer that they'll be sets of identical twins. Medical professionals say the odds are around one in a million.

In July 2025, a decade after British lawmakers signed off on allowing three-parent IVF, scientists announced that eight healthy babies had already been born using this approach. The news was included in a pair of research articles published in a peer-reviewed journal that noted the oldest kids were already more than two years old, and that they were hitting developmental milestones as expected.

An 18th-century Russian woman gave birth to 69 children through 27 pregnancies, with an unbelievable 16 pairs of twins, seven triplets, and four quadruplets.

Gynecologist Patrick Steptoe and his collaborator Robert Edwards, a biologist, attempted to fertilize a human egg cell in a petri dish 101 times before finally succeeding. This resulted in the birth of Louise Brown—at the time referred to as a "test tube" baby—in 1978, who was born into the spotlight.

Columbia University researchers created four embryos using mitochondrial replacement therapy for four female patients who didn't want to pass on mitochondrial diseases to their children. Yet US law restricts the researchers from implanting the embryos so they remain frozen.

Pregnancies involving three kids or more have dropped 62% from 1998 to 2023, a trend that the Centers for Disease Control and Prevention links to fewer embryo transfers during assisted reproduction procedures—a transition prompted by more refined techniques and technical advances. Though multiple births can occur naturally, often pregnancies involving multiple births have been the result of efforts to ensure pregnancy success by transferring multiple embryos.

Taking pictures of your kids is a huge headache now, but it was even harder for mothers in the Victorian era, when camera technology made posing for photographs difficult. These weird photos will show you how these mothers got their kids to sit...

The healthy baby boy's mother carried genes for a rare mitochondrial disease called Leigh syndrome and after multiple miscarriages the family opted to try the controversial procedure. It was conducted by a US doctor in Mexico. The procedure is prohibited in the United States.

It was the second country, after the UK, to legalize the procedure, which is still prohibited in the US. There are more than 300 rare mitochondrial diseases that can be passed from a mother to her offspring.

Almost all children likely used to contract poliovirus, but scientists suggest that when infants encountered it very early in life—due to poorer conditions and hygiene—they still had some maternal protection from pregnancy or through breastmilk, so the symptoms were more flu-like.

While birthing twins has been a rare occurrence for humans, research suggests that twins were actually the norm much further back in primate evolution. It’s proposed that single-childbearing turned out to be critical for the evolution of larger babies with larger heads. Discover more about the shift that gives insight into primate evolution.

Two reporters from The Atlantic tell the story behind their effort to track down the first diagnosed autism patient, Donald Gray Triplett, in Forest, Mississippi, and how his life turned out decades later.

The Two-Headed Calf MOOseum in San Francisco contains 50 taxidermied cow heads, all of which are paired with another one. They are the result of rare genetic mutations called polycephaly, that is, two-headedness. The museum is run by punk musician Henry Rosenthal, who first became captivated by the rare phenomenon in his 20s. Learn more about the exhibit here.

The non-identical twins, who would also be half-siblings, result from a rare biological phenomenon called heteropaternal superfecundation. Britain's first known twins with different dads, featured in this article, learned of each other's existence in recent years, when they were both 45. They discovered each other after taking DNA tests from Ancestry, a genealogy company.

Researchers at a hospital in the US have successfully used artificial wombs to care for preterm lambs and are now looking at the possibility of human trials. This nine-minute video includes interviews with the researchers and explains the reasoning...

This online memorial for families who experienced the unexpected death of a fetus 20 weeks or older is the result of ProPublica reporters inviting 60 families to share their baby's name and answer some questions about their unfulfilled wishes for their children. About 21,000 babies are stillborn in the US annually. About the same number of children die in the US during their first year of life.

That year, about 40% of the babies were born to unmarried parents, and about 32% of the births were born via cesarean. On average, mothers were 27.5 years old when they had their first child.

The Alabama Supreme Court's 2024 ruling that embryos created through IVF are legally children has had a chilling effect on the fertility industry. A few centers for reproductive assistance paused egg fertilization, and others are questioning where the legal argument will lead. The decision has some surprising implications for the future of IVF technology, including techniques that haven't yet been invented.

Professional photographer Ken Heyman discovered a 50-year-old box of photos labeled "Mothers" in his storage unit, with images depicting various mothers with their children in touching, candid scenes. Check out the finest of the group with this gallery.

The child, born in May 2020, was selected by her parents to optimize for certain health qualities based on an analysis of her multifactorial genes by a New Jersey-based company called Genomic Prediction. Her embryo was selected for implantation based on polygenic risk scores for heart disease, diabetes, and cancer.

Among the thousands of children who were brought to Great Britain from Nazi-controlled Europe during the Kindertransport rescue operation were Irene and Helga Bejach, who spent seven years living with the Attenboroughs. Irene contributed to David's interest in the natural world by giving him a piece of amber containing prehistoric creatures.

A handful of girls were stricken with bizarre twitches, tics, and spasms — all apparently involuntary. Some believed the incident to be conversion disorder, an illness where emotional troubles have physical symptoms.

In 2023, researchers at UC Davis performed the first-ever fetal stem cell transplant, attempting to cure a case of spinal bifida prior to childbirth using stem cells derived from the placenta. The trial, and others including an effort to treat muscular dystrophy, highlight the potential power of stem cell therapy.

Some critics of this approach worry that any genetic manipulation will both culturally and technologically normalize the idea of "designer babies"—embryos that are manipulated or selected based on physiological characteristics including height, eye color, athletic ability, and intelligence.

The three sisters and one brother recreated a professional photo taken of them in classic 1980s garb. They captured a TikTok of their parents' hilarious reactions that went viral.

This podcast details Jahi McMath's highly controversial case. She was declared brain-dead in 2013 following surgical complications, but her family, citing religious beliefs, kept her connected to a ventilator for the five years that followed. She continued to grow and went through puberty before being issued a second death certificate in New Jersey.

The field offers hope to thousands of families annually, but it is also largely unregulated, and for a small number of parents, things can go terribly wrong.

Scientists are working to create artificial wombs that would help preterm babies survive their early entry into the world. But how much help could this technology provide, and how much of a problem are preterm births? This article details some of...

Though the topline promise of this approach is avoiding passing on mitochondrial diseases, some researchers and companies have been eyeing its potential for helping with female infertility, since faculty mitochondria may contribute to the condition. Recent research suggests this approach could be promising.

A look at the companies offering surrogacy to the ultrarich—including Chinese men taking their reproductive cues from Elon Musk.

This revelation, confirmed in 2016, marked the first time that a mosquito-borne disease was known to cause birth defects. Fetuses exposed to the Zika virus during pregnancy sometimes suffer from neurological complications and microcephaly, a small-headed condition associated with neurological development issues and impairment.

Amid pre-World War II diplomatic efforts in June 1939, King George VI and Queen Elizabeth I (not her better-known daughter, Elizabeth II) became the first reigning British monarchs to visit the US—163 years after the colonies declared independence from Great Britain. The five-day meeting began with two formal days in Washington, DC, before concluding at FDR's estate in Hyde Park, where the monarchs reportedly enjoyed hot dogs for the first time.

This site allows you to see how your life would change if you were one of the 251 people born this minute in a new place. See stats on the average life expectancy, child mortality, income, and other major factors in these countries, compared to life in the country where you already live.

In 2022, 251,542 patients tried assisted reproductive technologies—most commonly IVF—resulting in more than 98,000 infants. Those children represent around 2.6% of the babies born in the US.