The origin of LASIK eye surgery, from a lab incident to federal funding and widespread use

After a University of Michigan engineering student suffered retinal burns from an ultrashort pulse laser, researchers realized it could be used to reshape the cornea and improve a person's vision with greater precision than a scalpel and earlier laser technologies. Agencies, including the National Science Foundation, the National Institutes of Health, and the Department of Energy, provided funding to develop and commercialize the procedure.

Corrective vision technologies rely on the bending of light waves

When focusing on an object, muscles change the shape of the lens, which refracts incoming light such that it focuses at the retina. If the cornea is unable to bend light correctly, lenses or contact lenses can provide supplemental refraction to ensure a focused image is produced.

See how cataracts—a leading cause of vision loss globally—form and how sound waves are often used to help remove them.

Lasers help build the layers of circuit components in microchips

During the photolithography process, light is projected through a blueprint onto a light-sensitive chemical layer on silicon wafers, etching patterns that become transistors through a series of successive reactions. These processes require significant electricity, as only about 2% of photons reach the wafer.

Laser technology powers communication, medical and manufacturing tools

Lasers are used when scanning groceries, printing documents or undergoing cosmetic procedures to enhance efficiency, precision and accuracy. Missile defense, targeting and optical communication systems have made using laser technology habitual in the military.

Restoring vision in impaired patients via CRISPR

Since CRISPR was revealed as a gene editing tool in 2012, it has been on an accelerated track to real-world applications. Among other clinical demonstrations, doctors have now injected a CRISPR treatment directly into eye cells, helping vision-impaired patients see shapes and colors again.

Laser skin treatments can promote the production of collagen

Skin resurfacing vaporizes the top layer of skin to reveal healthier, new skin, while collagen can give the skin structure and elasticity. Such procedures treat scars and burns, but may leave light spots on the skin.

Why surgeons implant teeth into eyes

What if the thing that restored your vision… was your own tooth? That’s exactly what happened to Brent Chapman. After 20 years without sight, a bizarre surgery using his tooth as a lens restored his vision.

New eye implant clinical trial recruiting in 2026

University of Southern California researchers have launched a phase 2b clinical trial of a stem cell implant designed to restore vision in people with advanced dry macular degeneration. Patients will be randomized to receive the stem cell implant or a simulated procedure and placebo implant. This type of larger, second-stage clinical trial is designed to confirm efficacy and dosing and to look for side effects. It's one of the stages that precedes the US Food & Drug Administration approval of a device.

Watch how doctors examine leprosy patients for signs of vision impairment

Clinicians must screen for symptoms of eye and vision damage in leprosy patients, including loss of sensation, reduced blink reflex, and inability to close or keep the eyes closed.

In a first, eye prosthesis has restored sight to macular generation patients

In a clinical trial, 27 of 32 participants with advanced macular degeneration regained enough vision to read books, food labels, and subway signs about a year after receiving a prosthetic retina device. This is the first device to restore functional vision to patients with incurable vision loss, though in this case they can only see in black and white, with no shades in between.

Removal of different color tattoo inks may require multiple lasers

Light needs to be absorbed by ink particles to break them down into small enough pieces for the immune system to eliminate. Color ink reflects, rather than absorbs, lasers of the same color, while black ink absorbs all colored lasers.

Using brain implants to restore vision

Several companies are attempting to create brain-computer interfaces that skip over retinas and optic nerves to allow visual input to go straight to the brain, potentially restoring some sight to the blind. Clinical trial findings suggest restored sight is sparse and manifests differently than a sighted person might expect, appearing as specks of "light" clusters called phosphenes to help differentiate one's surroundings.

Lasers could be the most cost-effective tool for clearing dangerous space debris

A NASA study found that lasers from ground- and space-based systems could utilize the momentum of light to safely push smaller debris out of their orbits. These systems would need to be accompanied by amendments to international space law, which prevents any nation from touching debris from another country, among other strategies.

Stereolithography uses light to fabricate objects in layers via chemical reactions

Specific locations in a tank of light-sensitive liquid resin are exposed to projected light, causing them to cure onto a build platform. The resulting cross-section of hardened plastic is moved slightly away from the light source, exposing it to resin once more, and the process repeats to produce successive layers.

The construction of LIGO needed to compensate for Earth's curvature

Across the 4-kilometer (2.5-mile) arms, the height of Earth's surface falls by almost a meter, preventing the lasers traveling within the arms from meeting the mirror at the end of each. Concrete slabs built beneath the arms help keep them level and provide structural support against seismic vibrations.

How lasers have become a go-to in archaeology

Archaeological teams now have another item to pack with their trowels: Lasers. Researchers' approach to unsurveyed land has been transformed by light detection and ranging technology. LiDAR has helped archaeologists break new ground and uncover...

Laser procedures have made tattoo removal much more common

An increasing number of Americans, including high-profile celebrities, get tattoos removed because laser removal has become more advanced and cost-effective. The tattoo industry is adjusting to this mainstream trend.

Laser-etched electric charges guide toner during laser printing

When sending a print job, the file data generates an image that a laser maps positively charged regions onto a drum separately for each color toner. Once the negatively charged toner is applied where it was electrically attracted, heat and pressure fuse it onto the paper.

Laser disc technology stores binary data in etched pits and lands

The pits are dips in the LaserDisc, CD, DVD, or Blu-ray surface that do not reflect the laser from the optical drive back to the photoelectric cell, resulting in a coded zero. Lands are reflective plateaus on the surface that code for a one.

The macula is a small area in the center of the retina

This part of the eye—roughly the bullseye of the back of the eye—is responsible for processing the central vision of the eye. Degradation of the macula, formally called macular degeneration, leads to symptoms including blurred vision, the need for brighter lighting, and difficulty recognizing faces. The condition doesn't affect peripheral vision, but if you lose central vision, you can still be considered blind.

Self-driving car companies like Waymo use lidar technology for navigation

By firing thousands of laser pulses in all directions, lidar systems construct 3D maps of a car’s surroundings, even in environments with limited lighting. The technology has also been incorporated into iPhones and the Vision Pro headset to improve camera focus.

Scientists create contact lenses that give you infrared vision

Scientists have created lenses that use nanoparticles to convert infrared light into visible light, allowing human eyes to observe previously invisible parts of the electromagnetic spectrum. This technology may help colorblind individuals by converting colors they cannot see into wavelengths they can.

Photolithography etches circuit components into a semiconductor wafer

A high-energy laser is fired at molten tin droplets, turning them into plasma that releases the ultraviolet light needed to burn the wafer's photoresist layer. A mask controls what parts of the wafer are etched for subsequent chemical processing.

Fiber lasers used for metal engravings can’t burn your skin

These devices use diodes and mirrors to create pulses of light that vaporize metal in billionths of a second, though at wavelengths that cannot react with organic material. Pulse width, power, and speed adjustments can produce white, black, and even colored patterns through controlled heat reactions.

Holograms are produced by shining light through recordings of interference patterns

When one half of a split laser beam that was reflected off the surface of an object recombines with its other, unreflected half, the two produce an interference pattern that becomes etched onto holographic film. When light shines through the back of the film, it reacts with the pattern to create the reflected light, projecting the original object.

The body can remove tattoos after they are broken down by laser

Tattoos place blobs of ink below the surface layers of the skin in packets too large for white blood cells to clear out. By breaking the ink into smaller pieces, they can be processed by the immune system, which is responsible for removing foreign matter.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

The history of contact lenses may have begun with Leonardo da Vinci, who developed a concept of vision correction based on placing a substance directly on the eye's surface.

By 2028, a space trash-avoiding maneuver is expected to occur every 18 seconds

As the number of active Starlink satellites increases, greater efforts will be required to keep low Earth orbit free of debris, sparking a new technological space race. NASA has found that using lasers to manage small and medium debris could save up to $9B over 30 years.

How to cook food with lasers

Creative Machines Lab at Columbia Engineering have developed a system of software-controlled lasers to cook food with precision, retain moisture with the final-cooked product, brown food within its original packaging, and create an entirely new meal creation process for a consumer. Watch this three-minute video to see for yourself.

Despite the visibility of lasers in space battles within science fiction, they are impossible to see in outer space unless they are pointed directly at an observer.

What did people do before eyeglasses were invented?

An estimated two-thirds of the world's adults use a form of prescription glasses or contacts, proof spectacles were a godsend when they were invented in 1286 CE. But what did people do before that? Different tools were used for distinct vision problems, but some would use magnifying lenses, clear emeralds, and more. Watch this video for a historical explanation.

Experience a century of America's healthcare advances with this medical visualization, tracing a sampling of healthcare innovations from head to toe.

Lidar's discoveries: 32 forts revealed by the laser tech

Lidar is a cutting-edge tool using lasers from an aircraft to map the elevations of huge swaths of land across the world. This technology has been especially effective in archaeology. It has revealed dozens of lost major historical sites concealed beneath overgrown brush and forests. From Canadian forts to Mayan settlements, check out these 32 significant finds from lidar.

A map of the moon, using lidar

When planning to land on the moon, knowing the topography matters. This map of the lunar surface was created by using 6 billion measurements from NASA's Lunar Orbiter Laser Altimeter, a type of lidar. Check out the technically accurate depths of craters and ancient oceans on our beloved lunar neighbor with this fun, impressive map.

Scientists have proposed using lasers to push space trash into Earth's atmosphere

Such projects would allow most debris to burn up and no longer pose a risk to active satellites, telescopes, and astronauts on space stations. Enacting these plans would require substantial investments from private and governmental space agencies and overcoming international laws that prevent the removal of another country's space equipment.

In LIGO's interferometers, light cancels itself out in the absence of gravitational waves

The devices are designed so that a laser is split into two beams that later recombine, canceling each other out and producing no signal. Changes in the lengths of the arms due to passing gravitational waves result in an interference pattern whose properties reveal features of the objects that created the waves.

NASA began investigating the healing properties of red light therapy in the 1980s, when researchers studying how LED lights could aid in photosynthesis noticed that their hands seemed to heal faster than normal under the lights.