Good morning. It's Thursday, July 18, and we're covering former President Donald Trump's upcoming RNC speech, a key to long life in mice, and much more. First time reading? Join over 3.5 million intellectually curious readers. Sign up here.
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Former President Donald Trump is set to speak in Milwaukee today, on the final day of the Republican National Convention. Tonight's speech will mark Trump's first public address since last week's assassination attempt. Watch it here.
The keynote address comes on the heels of three days of speeches, including from former rivals and primary challengers Nikki Haley, Ron DeSantis, and Vivek Ramaswamy. Yesterday, the convention heard from Trump’s pick for vice president, Sen. JD Vance (R-OH). Today, Trump will formally accept the party’s nomination for president in a speech he said he rewrote following last week’s attack. Trump has said the address will center on the need for unity.
Separately, President Joe Biden yesterday tested positive for COVID-19. The White House says he is experiencing mild symptoms and will isolate in Delaware. The news comes amid ongoing pressure from some Democrats—most recently Rep. Adam Schiff (D, CA-30)—to have Biden exit the race before his nomination in August.
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An intervention to suppress a protein in mice increased their lifespans by up to 25%, according to a new study.
The protein, interleukin-11, is found in a variety of species. In fish and tadpoles, it can help regenerate lost limbs. In humans, it is critical for bone and joint development. Still, prevalence of IL-11 can be associated with inflammation, linked to higher rates of chronic diseases, autoimmune disorders, and cancer.
Researchers tried two methods to suppress the protein in mice: In one group, they genetically engineered mice so they could not produce it. In another, they regularly administered an antibody later in life. Both interventions resulted in lower rates of cancer, healthier fur and muscles, and longer lives (see more, w/video).
The study marks the first to target IL-11 for antiaging and sparks hope interventions can achieve a similar impact in humans. It comes as clinical trials to suppress the protein are underway in people with cancer and fibrotic lung disease.
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Nominations for the 76th annual Primetime Emmy Awards were announced yesterday, with Netflix topping all networks with 107, followed by FX's best showing ever with 93. HBO dropped to third for the first time since 1996 after its flagship series "Succession"—the best drama winner in three of the last four years—ended last year.
FX's Japanese historical epic "Shōgun"—based on James Clavell's 1975 novel—received the most nominations at 25, followed by the network's "The Bear" with 23, a record for a comedy. This year marks only the second time an Indigenous actor was nominated, with three receiving the nod. Longtime "Survivor" host Jeff Probst returned to the lineup after 13 years.
Due to last year's writers and actors strikes in Hollywood, 33% fewer series (229) were submitted for awards consideration. The ceremony will be broadcast live on Sept. 15 (ABC, 8 pm ET). See the full list of nominations here and noticeable absences here.
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Sports, Entertainment, & Culture
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> The 152nd British Open kicks off today from Royal Troon Golf Club in Scotland; see preview and opening round tee times (More)
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> "Rust" armorer Hannah Gutierrez-Reed requests her March conviction be tossed after Alec Baldwin's case dismissal (More) | Naomi Pomeroy, James Beard Award-winning chef and "Top Chef Masters" star, dies at 49 in tubing accident (More)
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> Angel City FC becomes world's most valuable woman's sports franchise after Willow Bay and her husband, Disney CEO Bob Iger, buy majority stake, valuing the soccer club at $250M (More)
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> The hallucinogen psilocybin temporarily resets entire brain circuits that govern a person's sense of space and time when taken at high enough doses; study sheds light on the mechanism behind "tripping" on the drug (More)
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> Engineers unveil smallest, lightest solar-powered drone to date; vehicle is roughly 8 inches in size and can fly indefinitely in the sun (More)
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> Crown-of-thorns starfish larvae, a prolific eater of coral reefs, thrive on toxic blue-green algae; discovery suggests increased presence of the bacteria could drive the starfish population, further threatening reefs (More)
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> US stock markets close mixed (S&P 500 -1.4%, Dow +0.6%, Nasdaq -2.8%); Nasdaq records worst day since December 2022 as tech stocks fall on report of Biden administration considering trade restrictions against China (More)
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> Ray Ban-maker EssilorLuxottica to buy streetwear brand Supreme from VF Corporation for $1.5B; deal represents the eyewear maker's first venture into apparel (More)
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> United Airlines reports 23% year-over-year rise in Q2 profits, partly due to demand for international travel (More)
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In partnership with The Ascent
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> Department of Homeland Security's inspector general announces an investigation into Secret Service's handling of Saturday assassination attempt (More) | House Oversight Committee subpoenas Secret Service director (More)
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> US military to dismantle Gaza pier designed to carry aid to Palestinians via Cyprus after being damaged by weather; future aid will be delivered to Ashdod, Israel, and transported by truck (More) | See latest updates on the war (More)
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> Former CIA analyst Sue Mi Terry charged with espionage, accused of spying for South Korea in exchange for $37K and gifts including luxury goods, bags, and meals (More)
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> A Tale of Alzheimer's
The Guardian | Michael Aylwin. When Alzheimer's came for Vanessa Aylwin, she was in her 40s, a mother to two young children. Michael Aylwin recounts the slow and painful journey of his wife's decline and explores how well-meaning efforts to raise awareness about the disease can obscure the toll it exacts. (Read)
> Wanted: a Friend
Esquire | Kelly Stout. When Kelly Stout realizes she has many friends—but no one to grab a beer with on a Tuesday night—she embarks on a challenge: make a new friend in less than a month. (Read)
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Vanguard vs. Fidelity vs. Schwab
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*Disclosure: "Journal of Retirement Study Winter" (2020). The projections or other information regarding the likelihood of various investment outcomes are hypothetical in nature, do not reflect actual investment results, and are not guarantees of your future results. Please follow the link to see the methodologies employed in the Journal of Retirement study.
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