Good morning. It's Monday, Nov. 10, and we're covering the status of the government shutdown, the most famous Christmas tree, and much more. First time reading? Join over 4.5 million insatiably curious readers. Sign up here.
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Breaking news: Senators reportedly reached an agreement yesterday to reopen the government. The deal involved at least eight Democrats and is projected to take days to move through the House. It would require funding much of the government through January and some departments—including the Department of Agriculture—for a full year. See live updates here. |
The world’s largest global climate meeting—the 30th Conference of the Parties—begins today in Belem, Brazil. Nearly 200 countries will send representatives; the US will not send an official delegation.
COP30 comes 10 years after 195 countries adopted the US-led Paris Agreement, in which each committed to taking steps to reduce global warming to 1.5 degrees Celsius above preindustrial levels. Since then, countries have largely failed to meet commitments, and emissions have continued to rise, albeit less quickly. If warming continues at its current pace, researchers project global temperatures will rise 2.5 to 2.9 degrees Celsius by the end of the century, down from the up to 3.8 degrees Celsius predicted a decade ago. The UN expects global warming to cross the 1.5 degrees Celsius threshold by 2035.
President Donald Trump pulled out of the Paris deal in both terms, citing the economic burden, including billions of dollars in donations to developing countries.
PS: See what we've learned about climatology via 1440 Topics here. |
Rockefeller Christmas Tree |
The Rockefeller Christmas tree arrived in New York City Saturday, kicking off a tourist season that will see an estimated 750,000 people visit daily—more than 125 million people each year.
The tradition dates back to 1931, when construction workers at what would become Rockefeller Plaza pooled resources to buy a 20-foot balsam fir tree (see more, w/video). Since then, the tradition has involved larger trees, typically a Norway spruce lit with more than 50,000 LED lights and topped with a 900-pound Swarovski-crystal star. This year’s tree is a 75-foot-tall, 11-ton Norway spruce from East Greenbush, New York, donated by a woman in honor of her late husband. The tree will be lit from Dec. 3 to mid-January, after which the wood will be donated to Habitat for Humanity.
See an interview with Erik Pauze, the gardener who selects the tree each year, here (w/video). |
CRISPR Cholesterol Breakthrough |
A new gene-editing drug could effectively cure high cholesterol in certain patients via a one-time shot, according to results from a small clinical trial revealed Saturday. The treatment lowered “bad” cholesterol and triglycerides by about half with no apparent side effects after two months.
Cholesterol is a waxy substance that comes in two forms, low- and high-density lipoprotein (LDL and HDL), while triglycerides are energy stored as fat in the bloodstream. About 25% of cholesterol comes from diet, while the rest is produced by the liver and intestines. LDL cholesterol tends to adhere to blood vessel walls, causing plaque buildup and increasing the risk of heart disease. The new drug “turns off” a specific gene—ANGPTL3—responsible for producing LDL and triglycerides.
Around 1 in 300 people has a mutation that disables the gene, offering natural protection against heart disease, the leading cause of death in the US (see more). |
Editor's note: In our Sunday newsletter, we mistakenly wrote that the MLB has 32 teams. There are 30 teams. Thank you to our readers for pointing out the error! |
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In partnership with Simple |
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The Hormone Hindering Your Weight Loss |
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Sports, Entertainment, & Culture |
> McLaren's Lando Norris wins Formula 1 Grand Prix in São Paulo, Brazil, extending world championship title (More) |
> Former NFL Commissioner Paul Tagliabue dies at age 84; Tagliabue led the league from 1989 to 2006 (More) | Indiana Hoosiers wide receiver Omar Cooper Jr. scores game-winning, toe-tap touchdown in final seconds, defeating Penn State (More) |
> Creator behind AI actor Tilly Norwood says 40 other AI actors are in development (More) |
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In partnership with Elf Labs |
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> NASA's ESCAPADE mission launches aboard a Blue Origin New Glenn rocket; twin satellites will orbit Mars, studying the effect of the solar wind on the planet (More) |
> Rare footage captures behavior of suckerfish hitching a ride on a humpback whale in the open ocean; video reveals the fish can detach from—and return to—the same spot each time the whale breaches (More, w/video) | Sign up for 1440 Science & Technology (More) |
> Scientists develop method to create gene-edited plant varieties from a single plant cell, cutting the process time from months to weeks (More) |
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In partnership with Vero3 |
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> US stock markets close mixed Friday (S&P 500 +0.1%, Dow +0.2%, Nasdaq -0.2%); tech-heavy Nasdaq closes its worst week since April (More) | Bureau of Labor Statistics misses second straight jobs report due to government shutdown, unemployment estimated at 4.5% (More) |
> Pfizer outbids Novo Nordisk to buy obesity drugmaker Metsera for $10B; deal is up from a $7.3B offer in September (More) |
> Cryptocurrency bear market continues, with the total market cap of all currencies down 20% since Oct. 6 record high; fall erases almost all gains in 2025 (More) |
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> Super Typhoon Fung-wong kills two people, forces more than 1 million to evacuate as it makes landfall on the Philippines' northeastern coast (More) |
> President Donald Trump meets today with Syrian President Ahmad al-Sharaa—the first leader from Syria to visit the White House since 1946 (More) | Hamas returns remains of Israeli soldier Hadar Goldin, killed in Gaza in 2014 (More) |
> The UK, France, and Germany are supplying Belgium with anti-drone equipment and staff after the country's main airport was forced to temporarily close last week amid drone spotting (More) |
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In partnership with Simple |
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Clickbait: Should children have skincare products?
Historybook: Protestant Reformation leader Martin Luther born (1483); US Marine Corps is founded (1775); Singer and actress Jane Froman born (1907); "Sesame Street" debuts (1969); Bill Gates announces Windows 1.0 to public (1983). |
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*Disclosure: This is a paid advertisement for Vero3 Limited’s Regulation CF offering. Please read the offering circular at https://invest.vero3.com/. Timelines are subject to change. Listing on the NASDAQ is contingent upon necessary approvals, and reserving a ticker symbol does not guarantee a company’s public listing. |
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