Good morning. It's Tuesday, March 24, and we're covering a fatal collision at a major New York airport, a new antidote against Lyme disease, and much more. First time reading? Join over 4.7 million insatiably curious readers. Sign up here.
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New York's LaGuardia Airport was closed for hours yesterday after an arriving Air Canada airplane carrying 76 people collided with a fire truck Sunday night. Two pilots were killed, and more than 40 people—including two people aboard the fire truck—were injured, some critically.
Audio from the crash suggests air traffic controllers may have been focused on a separate incident—assisting another aircraft's pilot who had made multiple attempts to take off—when the collision occurred around 11:40 pm ET. One controller can be heard clearing a Port Authority fire truck to cross the runway before yelling “stop, Truck 1, stop” (listen here, w/photos). The truck was responding to a smell reported on a United flight. The incident marks LaGuardia's first fatal crash since 1992.
Separately, ICE agents were deployed at airports nationwide yesterday to support TSA agents, as the partial government shutdown entered Week 5 (see photos). The Senate, meanwhile, confirmed Markwayne Mullin to lead the Department of Homeland Security, which oversees the agencies. |
Pfizer is seeking regulatory approval for a Lyme disease vaccine that showed 73.2% efficacy in a late-stage clinical trial. If cleared, it would be the first human vaccine against the tick-borne disease approved in over two decades.
Lyme disease is transmitted to humans through the bite of an infected deer tick, with symptoms ranging from a rash to fatigue and arthritis. Roughly 500,000 Americans are diagnosed with or treated for the bacterial infection annually (explore prevalence near you), and most fully recover after a 10- to 14-day course of oral antibiotics. Some patients—including several celebrities—report persistent symptoms, though chronic Lyme disease is not recognized by conventional medicine. The last human Lyme disease vaccine was introduced in 1998 but withdrawn in 2002 after unproven side-effect concerns sank demand.
Pfizer's vaccine application may face scrutiny; too few trial participants contracted Lyme disease to prove the shot was effective in at least 20% of the worst cases—a key metric.
PS—A recent edition of our 1440 Health & Medicine newsletter explored Lyme disease. See the best resources we found on the topic here, and sign up for the weekly deep-dive series here. |
'Hannah Montana,' 20 Years Later |
Today marks the 20th anniversary of "Hannah Montana," the Disney Channel series that turned a then-13-year-old Miley Cyrus into a global pop star and bonded a generation of viewers.
Cyrus, now 33, returns as her blond-haired alter ego for a one-hour special (3 am ET, Disney+ and Hulu), featuring an interview, unseen archival footage, and a new song. Over two decades, Cyrus underwent one of pop culture's most dramatic reinventions, evolving into a Grammy-winning artist behind hits like "Flowers," "Wrecking Ball," and "Party in the USA." Read reflections from Cyrus on getting sober; reuniting with her dad, Billy Ray Cyrus; and why she says she wasn't trying to kill Hannah Montana. Listen to her top songs here.
The 2006 "Hannah Montana" premiere drew 5.4 million viewers—then a Disney Channel record—while a 2007 episode remains the network's most-watched live-action broadcast, with 10.7 million viewers. Its Season 1 soundtrack was also the first TV soundtrack to debut at No. 1 on the Billboard 200. |
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In partnership with Timeline |
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Experts Identify Major Culprit Behind Aging |
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It’s well known that as we age, we can expect less energy, more tiredness, and weaker muscles, but did you know the root of this issue lies at the cellular level?
Starting in our 30s, the mitochondria, responsible for 90% of your body’s energy, take on damage with time and our cells slowly lose the ability to repair it. This decline wears down our physical strength and endurance, lowering quality of life over time. But, recent discoveries have revealed a way to restore cellular energy and support healthy aging.
Clinically proven Mitopure® is a breakthrough over 15 years in the making that replaces aging mitochondria and helps to rebuild new ones, increasing cellular energy. The results? Studies found participants saw muscle strength and endurance increase without any changes to exercise. Ready to live better for longer? 1440 readers can take 40% off Mitopure, while supplies last, with code 1440SPRING. |
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Sports, Entertainment, & Culture |
> No. 10 Virginia upsets No. 2 Iowa to reach NCAA women's Sweet 16; games resume Friday (More, w/full bracket) | NCAA men's tournament sees best TV start since 2011, averaging 9.8 million viewers in first three days (More) | WNBA players reach seven-year collective bargaining deal ahead of 2026 season (More) |
> Bill Cosby found liable of drugging and raping waitress in 1972, ordered to pay $19.25M in past and future damages and $40M in punitive damages (More) |
> OnlyFans owner Leonid Radvinsky, under whom the adult content platform's revenue grew over $1.3B in five years, dies of cancer at age 43 (More) | "Superman" actress Valerie Perrine dies at age 82 after a battle with Parkinson's disease (More) |
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> Astronomers forge new field called "extragalactic archaeology," using changes in gas patterns to trace the evolution of a distant galaxy over 12 billion years of cosmic time (More) |
> Droughts may increase rate of antibiotic-resistant microorganisms in soil, causing hot, dry regions to face higher prevalence of antibiotic-resistant infections (More) |
> Honey bees "waggle dance," which directs hive mates to food, varies depending on the size and makeup of their audience (More) | Watch the dance (More) |
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In partnership with Frontieras |
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Unlocking $2.1 Trillion in Energy Potential |
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> US stock markets close up (S&P 500 +1.2%, Dow +1.4%, Nasdaq +1.4%), oil prices fall as President Donald Trump postpones strikes on Iran's energy infrastructure for five days (More) | The states hit hardest by fluctuating gas prices (More, w/map) |
> French food giant Danone, maker of Evian water and Activia yogurt, agrees to buy UK nutrition startup Huel (derived from "human" and "fuel") for roughly $1.2B (More) |
> US Sens. Adam Schiff (D-CA), John Curtis (R-UT) introduce bipartisan bill banning prediction market contracts tied to sports events or casino-style games (More) | How prediction markets differ from sportsbooks (More) |
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> US Supreme Court hears case on mail-in ballots, could limit states from counting mail-in ballots received after Election Day but postmarked day of or beforehand (More) | See map of 14 states that could be impacted (More) |
> Greece begins criminal trial against railway operators and transportation officials over February 2023 train collision that killed 57 people; the trial is expected to last two years (More) |
> Colombian military transport plane crashes shortly after takeoff with more than 100 soldiers on board; at least 80 people were reportedly rescued alive (More) |
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> Culture Shift
Asimov Press | Rachel Dutton. How fermented foods shaped the immune system of humans and great apes over time, and why foods like sauerkraut may be important for the human body. (Read) |
> One Dad, One Hundred Babies
The Journal | Staff. A look at the companies offering surrogacy to the ultrarich—including Chinese men taking their reproductive cues from Elon Musk. (Listen) |
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In partnership with Timeline |
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Keep Strong Muscles As You Age |
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Please support our sponsors! |
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Historybook: World famous magician Harry Houdini born (1874); Author Jules Verne dies (1905); Dorothy Height, civil and women’s rights activist, born (1912); Exxon Valdez oil tanker runs aground, eventually spills 11 million gallons of oil (1989).
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