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All your news in a single email. We scour 100+ sources so you don't have to. Culture, science, sports, politics, business, and more - all packaged in a 5-minute read below.
Need To Know.
Iran Sanctions Kick In.
President Trump signaled he would not intervene in the renewal of sanctions against Iran, allowing a bevy of restrictions on the country's economy to kick in today. The White House made one exception, deciding to not penalize oil imports into Iran. The sanctions, which primarily target the financial and energy sectors, had been lifted as part of the multilateral Iran nuclear deal from which the administration withdrew from in May. Iran's banking system will be largely cut off from global markets, and any company doing business with Iran will be prohibited from doing business in the US. Iranian officials are confident they can withstand the restrictions despite already official inflation and employment rates above 10%. The restrictions kick in just after the 39th anniversary of the storming of the US embassy, when students held 52 Americans hostage for 444 days. 

In related news, new reports detailed how a worldwide collapse of a CIA informant network began in Iran. 
Amazon Close to HQ2 Decision.
Amazon may be leaning towards the Northern Virginia town of Crystal City as the location for its second headquarters, according to reports leaked over the weekend. The company has been in discussions with around 20 major metro areas around the country for its so-called HQ2, which is expected to bring around $5B in direct investment and 50,000 jobs over 10 to 15 years. The leaked details suggested that the company was also considering areas outside New York City and Dallas, TX, though officials were quick to dismiss the report, saying no decision has been made. Crystal City lies just outside Washington, DC, leading many to speculate that the online retail giant was considering proximity to the federal government as a bonus. Cities have been in an intense competition (paywall) since HQ2 was announced - in addition to tax breaks and incentives, criteria included metro areas of over one million people, room to grow, and the ability to attract top tech talent (see where US tech talent is located).
Yoga Studio Rampage.
Three people died, including the shooter, and wounded five after a Florida man opened fire in an upscale yoga studio in Tallahassee on Friday evening. 40-year-old Scott Paul Beierle had served in the military and worked as a teacher at one point, and had a history of arrests for grabbing and harassing women on the campus of Florida State University. He also reportedly posted a number of misogynistic and racist videos online, at one point comparing himself to notorious mass shooter Elliot Rodger, who killed 6 and injured 14 on the campus of UC-Santa Barbara in 2014. Rodger was also invoked in a manifesto by Toronto killer Alek Minassian, who ran down 10 people and wounded 13 others in a vehicular attack in April of this year. All three self-identified as so-called "incels", an obscure subculture that has flourished online, harboring extreme misogynistic views. 
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In The Know.
Sports, Entertainment & Culture.
> Lelisa Desisa of Ethiopia wins his first NYC Marathon in a time of 2:05:59; Kenya's Mary Keitany is women's winner (More)
> Alec Baldwin arrested for assault and harassment for allegedly punching a man over a parking dispute (More)
> Spice Girls to announce UK reunion tour today; reportedly will not include Victoria "Posh Spice" Beckham (More)
Science & Technology.
> Machine learning algorithm helps identify which animal species are most likely to be hosts for deadly diseases (More)
> Study finds link between birth defects and age of fathers; risk increases beginning at paternal age of 35 (More)
> Amid opioid crisis, FDA approves new drug that is 10x stronger than fentanyl, citing military applications (More)
Business & Markets.
Brought to you by Policygenius: Insurance made easy
> Berkshire Hathaway, the conglomerate run by billionaire investor Warren Buffet, double last year's operating profit; company bought back $928M of its own stock (More)
> US adds 250,000 jobs in October, significantly beating estimates of 190,000; wages grow 3.1% year-over-year, the biggest jump since 2009 with unemployment rate holding at 3.7%, its lowest since 1969 (More)
> Pizza delivery and food logistics startup, Zume, receives first of two $375 million installments from investment fund SoftBank; Zume now valued at $2.25 billion (More)

> Need life insurance? Compare quotes, apply online, and get expert help with Policygenius (More)
Politics & World Affairs.
> Trump, Obama make final push for candidates ahead of 2018 midterm elections (More)
> Brent Taylor, mayor of North Ogden, UT killed by Afghan soldier he was training; Taylor was on a year-long leave of absence to serve in Afghanistan as part of the Army National Guard (More)
> Support for French exit from European Union gains steam; far-right group edges French president Emmanuel Macron's party in polling for European Parliament elections in May 2019 (More)
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Historybook: HBD Gone with the Wind actress Vivien Leigh (1913); Franklin D. Roosevelt is first and only US president elected to third term (1940); Saddam Hussein is sentenced to death (2006); HBD Android operating system from Google (2007).
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