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Good morning. It's Wednesday, Aug. 9, and we're covering a weight-loss drug that could improve heart health, a dark web child abuse investigation, and much more. First time reading? Sign up here.


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Need To Know

New National Monument

President Joe Biden, during a visit to Arizona yesterday, designated nearly a million acres of land just outside of Grand Canyon National Park as a national monument. The Baaj Nwaavjo I’tah Kukveni, or the Ancestral Footprints of the Grand Canyon National Monument, is the fifth such designation during Biden's presidency. 


The designation is meant to protect land considered sacred to Native American tribes in the area, including from all new uranium mining for energy use. Native tribes and environmental groups have said such mining activities would damage the Colorado River and nearby tribal sites. Uranium mining has already been restricted in the area since a moratorium went into effect in 2012; however, the restriction is set to expire in 2032. See an overview of how uranium is mined here.


Nearly 3,000 mining leases from 2012 will still be allowed to continue. Roughly 1.3% of known uranium sources in the US are located within the area near the Grand Canyon. About 5% of the country's total uranium sources are domestic, while the rest are imported (see data). 


Semaglutide Reduces Heart Risk

Pharmaceutical company Novo Nordisk's weight-loss drug Wegovy was found to significantly reduce the risk of major heart issues, according to a study released yesterday. Analysts suggest the results could help decrease the cost of the new class of semaglutide-based weight-loss drugs—including Ozempic—often labeled as nonmedical treatments by insurers.


The five-year study observed the effects of a weekly injection in over 17,000 obese patients over the age of 45 who have cardiovascular disease, reporting a 20% reduction in heart attacks, strokes, and cardiac arrests. The treatment consists of an appetite-suppressing gut hormone known as semaglutide, which has skyrocketed in popularity since being FDA-approved in 2021. Recent studies repeatedly have shown the drug's efficacy, with recipients seeing a 15% weight reduction


Roughly 40% of US adults are overweight or obese, a major risk factor for heart disease. An estimated one in four deaths results from heart disease each year in the US.


Dark Web Pedophilia Bust

Nearly 100 people have been arrested in the US and Australia as part of a dark web child abuse investigation, including 79 in the US and 19 in Australia, and 13 children have been rescued. The suspects in Australia are between the ages of 32 and 81, with many in careers that require a high degree of IT knowledge.


The news comes more than two years after FBI Special Agents Daniel Alfin and Laura Schwartzenberger—who were part of the 2015 takedown of Playpen—were fatally shot as they attempted to serve a search warrant at an apartment in Sunrise, Florida, for a man suspected of being in possession of child abuse material. Dubbed Operation Bakis, the investigation was formally launched last year when the FBI provided Australian authorities with information about a child abuse network on the dark web.


Over 80% of dark web traffic was found to relate to illegal porn, abuse images, or child sex abuse material. See why it’s hard to stop the spread of the material here.

In partnership with Timeline

Scientists Discover New Way to Fight Aging


Scientists have discovered a remarkable antiaging molecule called Urolithin A that can give our cellular powerhouses, the mitochondria, new life. This is a potential game-changer for healthy aging. Meet Mitopure® by Timeline Nutrition, the only clinically validated, highly pure Urolithin A supplement.


Did you know that ~90% of the food you eat and the air you breathe is used by your mitochondria to produce your body's energy? By our 30s, our mitochondria can become less efficient, leading to a reduction in energy production. But there's a way to counter this natural decline. When taken daily, Mitopure renews your mitochondria, increasing cellular energy. The results? Studies found participants saw muscle strength and endurance increase without any changes to exercise routines. 


Mitopure renews cells to a more powerful state. See for yourself; 1440 readers can try a free 3-day starter pack, while supplies last, with code 1440START.

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In The Know

Sports, Entertainment, & Culture

> Rapper Tory Lanez sentenced to 10 years in prison for 2020 shooting of Megan Thee Stallion (More) | Taylor Swift leads MTV Video Music Awards (Sept. 12) nominations with eight (More)

> The 2023 Women's World Cup quarterfinal set; see schedule and match previews (More) | Team USA announces its squad of 139 athletes set to compete in the 2023 World Athletics Championships (Aug. 19-27) in Budapest, Hungary (More)

> Jay-Z's Made in America festival canceled; Lizzo, who was recently sued by former dancers alleging sexual harassment, was tapped to headline (More) | DJ Casper, creator of dance hit "Cha Cha Slide," dies at 58 (More)


Science & Technology

> Stability AI, firm behind text-to-image generator Stable Diffusion, releases generative AI model that can produce large amounts of computer code on request (More)

> Researchers discover key driver of vascular dementia, where high blood pressure causes changes to arteries in the brain and results in neurodegeneration; findings may lead to new treatments targeting the root cause of the disease (More)

> Astrophysicists find first direct proof that gravity begins to depart from Isaac Newton's famous equation even at very low acceleration (More) | Newton, Einstein, and how gravity works (More)


Business & Markets

In partnership with The Ascent

> US stock markets close lower (S&P 500 -0.4%, Dow -0.5%, Nasdaq -0.8%) after Moody’s downgraded the credit ratings of 10 regional banks (More) | US regulators fine Wells Fargo and other Wall Street firms $549M for use of personal messaging apps for business dealings (More)

> US credit card debt up 4% over second quarter, tops $1T for the first time (More)

> Neuralink—implantable brain-computer interface maker founded by Elon Musk— raises $280M (More)

From our partners: Make 2023 your year for a one-card wallet. This card offers up to 5% cash back at places you likely already shop, a huge welcome bonus, and 0% intro APR into 2024 on purchases and balance transfers. All with no annual fee. Possibly making this card the only one you need. Learn more.


Politics & World Affairs

> Ohio voters reject ballot measure that would have raised simple majority threshold for passing future state constitutional amendments to a 60% supermajority (More) | US Supreme Court temporarily reinstates federal regulations of "ghost guns"—privately made firearms without serial numbers—while legal challenges proceed (More)

> Florida Gov. Ron DeSantis (R) replaces campaign manager with his administration's chief of staff in bid to revamp 2024 Republican presidential bid (More) | Eight candidates have qualified for the Aug. 23 first GOP primary debate (More)

> At least two people killed, more than 250,000 without power as of yesterday afternoon following intense storms Monday across the eastern US (More)

In partnership with Timeline

Science Reveals New Path to Healthy Aging


In clinical studies testing skeletal muscle in middle-aged and older adults, a healthy-aging molecule called Urolithin A increased strength and endurance by improving cellular energy—with no change in the participants’ exercise routine. Maintaining muscle function is a pillar of healthy aging.  


Mitopure®, the only highly pure Urolithin A supplement, is supported by 15 years of research, 11 clinical studies, and 56 patents. Don’t wait, try today … 1440 readers can try a free 3-day starter pack, while supplies last, with code 1440START.

Please support our sponsors!


Massive blue whale washes ashore in Chile.


Why scientists use zebrafish to study human blood disorders.


Thirty-six hidden messages in popular company logos


Turning movies into vintage paperbacks


The best US cities for cat lovers in 2023.


Why Barcelona's restaurants are turning away solo diners


How to turn your McDonald's drink into cotton candy soda.


An unexpected surprise during renovations. (w/video) 


Clickbait: Don't be a military-grade signal jammer


Historybook: The US drops atomic bomb on Nagasaki, killing over 40,000 (1945); Whitney Houston born (1963); Actress Sharon Tate, four others murdered by Manson Family (1969); Gerald Ford becomes US president as Richard Nixon resigns (1974); Musician Jerry Garcia dies (1995).

"Success doesn't change you. Fame does."

- Whitney Houston

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