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Good morning. It's Friday, Jan. 5, and we're covering a school shooting in the Midwest, the release of a disgraced Paralympic and Olympic star, and much more. First time reading? Sign up here.


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Need To Know

Iowa School Shooting

A sixth grader was killed and five other people were wounded after a shooter opened fire at a high school in the small Iowa town of Perry yesterday. The attack occurred just before the start of class during the morning drop-off period on the students' first day back from winter break.


The shooter, identified as 17-year-old student Dylan Butler, reportedly died at the scene from a self-inflicted gunshot wound. Butler, who was armed with a shotgun and small caliber pistol, is said to have posted to TikTok just before the attack, though the account was quickly disabled.  


The names of the victims have not been released; the five injured victims included four students and one administrator. All are expected to survive. 


Perry, located about 40 miles northwest of Des Moines, is home to around 8,000 residents, with the high school and middle school located together. The attack is believed to be the worst school shooting in state history by number of victims. 


Eli Lilly Launches Website

Pharmaceutical giant Eli Lilly launched a direct-to-consumer website yesterday, allowing its customers to receive third-party prescriptions for its drugs, including its newly approved weight loss injectable Zepbound (similar to Novo Nordisk’s Wegovy/Ozempic). Users can be connected to a telehealth service via the site to quickly receive prescriptions before placing an order. 


Roughly 70% of Americans are obese or overweight, a condition known to increase health risks. The market marks the next step in the rising use of GLP-1 agonists like Zepbound, which mimic a gut hormone stifling hunger and increasing insulin production. Studies have shown an average weight reduction of 15%, among a myriad of other health benefits (how it works). 


High demand for the treatments has strained supply chains and upended industries, prompting pivots from weight loss behemoth Weight Watchers and forcing food manufacturers to anticipate generational changes in eating habits. Pharmaceutical companies Pfizer and Amgen are expected to seek approval for their own versions this year in a market analysts expect to grow to $100B by 2035.


Pistorius Paroled

Oscar Pistorius, the South African former Olympic and Paralympic runner, will be released from prison today after serving half of his over 13-year sentence for the 2013 murder of his model girlfriend, Reeva Steenkamp.


Known as "Blade Runner," the 37-year-old is a six-time Paralympic gold medal winner and was the first double amputee runner to compete in the Olympic Games. He fatally shot Steenkamp in the early morning hours of Valentine's Day, claiming he mistook her for an intruder—prosecutors argued he shot her knowingly due to an argument. He was initially convicted of culpable homicide in 2014, roughly the equivalent to involuntary manslaughter in the US, before his conviction was escalated to murder by the Supreme Court of Appeal of South Africa in 2015, leading to a 13-year, five-month sentence in 2017. See details on the case here.


Upon release, Pistorius will participate in South Africa's restorative justice program, undergoing regular monitoring and participation in gender-based violence and anger management programs until his full sentence ends in December 2029.

In partnership with Timeline

Discovered, A 'Speed Limit' on Healthy Aging



“Newly energized cells may provide many more years of healthy life to people'' concludes a recent publication in top scientific journal Nature Metabolism, revealing the critical link between cellular energy and enduring health. As we age, cellular energy production naturally declines and, like a “speed limit,” restricts cellular function setting the stage for diminished health.


New research suggests a solution to energy decline and points to a remarkable molecule called Urolithin A. Derived from plants, Urolithin A is clinically shown to give our cellular energy generators, the mitochondria, new power. Mitopure® by Timeline Nutrition is the only clinically validated, highly pure Urolithin A supplement. Taken for 2 months, Mitopure can significantly improve cellular energy. Taken longer, Mitopure can increase skeletal muscle strength and endurance with no change in exercise


Mitopure increases your cellular energy speed limit. Start 2024 strong; 1440 readers can get 30% off their order of Timeline, while supplies last, with code 1440thirty.

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In The Know

Sports, Entertainment, & Culture

In partnership with Jambys

> ESPN and NCAA sign eight-year, $920M broadcast rights agreement; deal includes rights to broadcast 40 NCAA championships over the next eight years (More)

> Glynis Johns, Tony-winning and Oscar-nominated actress known for starring role in "Mary Poppins," dies at 100 (More

> The 81st Golden Globe Awards to be presented Sunday (8 pm ET, CBS); see predictions for each category (More) | Elvis Presley holographic concert to debut in London in November (More)

From our partners: Jambys makes super comfortable clothing that helps you maximize your relaxation at home. Designed by ex-Nike and Lululemon activewear designers, Jambys’ unisex performance inactivewear is made from premium fabrics that make you go "wow" on your first feel. Seriously, read the reviews. Just for 1440, Jambys has a special discount this weekend. Get cozy with an exclusive 20% off sitewide (yes, including sale items) using code 1440NY.


Science & Technology

> OpenAI to launch its online store featuring third-party GPTs next week; expected to be similar to Apple Store, with ChatGPT-based programs instead of apps (More) | Google begins phasing out the use of cookies, small autogenerated files that track user history on websites in between visits (More)

> New study finds genetic variant associated with male bisexuality also linked to higher rates of self-described risk-taking, fathering more children; findings may suggest the evolutionary advantage of the variant (More)

> Alzheimer's drug combined with targeted ultrasound found to be about 30% more effective in attacking brain plaques (More)


Business & Markets

> US stock markets close mixed (S&P 500 -0.3%, Dow +0.0%, Nasdaq -0.6%); Nasdaq falls for fifth consecutive trading session, its longest losing streak since October 2022 (More) | Peloton shares up 14% after company announces new fitness hub partnership with TikTok (More

> Walgreens beats earnings and revenue expectations; shares close down 5% after drugstore chain nearly halves quarterly dividend payout (More) | Ford reports 7.1% increase in US new vehicle sales in 2023, its best US sales year since 2020 (More) | French grocery giant Carrefour drops PepsiCo products over price hikes (More

> US weekly jobless claims drop to 202,000; figure from last week is lowest level since October (More) | December US private payrolls rose for fourth consecutive month (More)   


Politics & World Affairs

> US airstrike in Baghdad, Iraq, kills commander of Iran-backed militia group, comes amid rising tensions in the Middle East (More) | Islamic State claims responsibility​​​​​ for Wednesday's cemetery bombings in Iran that killed at least 84 people (More) | See previous write-up (More)

> Former President Donald Trump's properties and hotels reportedly received at least $7.8M in foreign payments (including $5.7M from China) during his presidency, per new report from House Oversight Committee Democrats (More) | See the report (More

> Weekend storm expected to bring significant snow to the US East Coast, with areas stretching from central Appalachia to the upper Northeast to see between 6 and 12 inches (More)



> The Return of the Cellphone Ban

USA Today | Alia Wong, Nirvi Shah. Most schools ended bans on cellphones in class a decade ago for safety and convenience, but a recent surge in new rule is prompting a reexamination. (Read)


> Only Earth Has Fire

PBS Eons | Staff. It took billions of years of photosynthesis on planet Earth—the only place in the universe where it's known to exist—to create the conditions for fire. (Watch)

> Gumbo Disinflation

Planet Money | Staff. (Podcast) As prices return to normal, national metrics used to indicate inflation sometimes conceal expensive outliers—like specific ingredients in, say, a bowl of gumbo soup. (Listen)


> Saving the Panama Canal

Bloomberg | Peter Millard, Michael McDonald. It's Panama's chief moneymaker, and an extended drought is permitting only 24 vessels to pass daily through the crucial trade route—14 fewer than the predrought level. (Read)

In partnership with Timeline

Urolithin A: A New Era in Healthy Aging


Maintaining muscle function is a pillar of healthy aging, but as we get older, our muscle integrity diminishes. In clinical studies testing skeletal muscle, a healthy-aging molecule called Urolithin A increased strength and endurance by improving cellular energy–with no change in the participants’ exercise routine.


Mitopure, the only highly pure, clinically validated Urolithin A supplement, is supported by 5 clinical studies and 56 patents. 1440 readers can get a FREE 3-day Mitopure Starter Kit, while supplies last, with code 3Day1440.

Please support our sponsors!


Visualizing history's major disease outbreaks


Entering "dry January," a look at Americans' booze habits.


Breaking down what makes up a $660 candle. (via YouTube)


The most anticipated movies for 2024


Opposites don't actually attract, science says.


NASA grabs a time-lapse from the Martian surface.


Local Virginia officials shut down TikTok's "Tunnel Girl."


Meet Hercules, the world's largest Sydney funnel-web spider.


Clickbait: Couple "recovers" thousands after dog eats pile of cash.


Historybook: Actress Jane Wyman born (1917); Dancer and choreographer Alvin Ailey born (1931); Construction of Golden Gate Bridge begins (1933); Scientist and inventor George Washington Carver dies (1943); Singer and congressman Sonny Bono dies in skiing accident (1998).

"The creative process is not controlled by a switch you can simply turn on or off—it's with you all the time."

- Alvin Ailey

Why 1440? The printing press was invented around the year 1440, spreading knowledge to the masses and changing the course of history. More facts: In every day, there are 1,440 minutes. We’re here to make each one count.


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