A Third Vaccine, Cuomo Allegations, and NASA's Secret Code Cracked
Johnson & Johnson's COVID-19 vaccine on the verge of approval, New York Gov. Andrew Cuomo (D) faces sexual harassment allegations, and more.
Good morning. It's Thursday, Feb. 25, and the US is close to having its third available COVID-19 vaccine—and this one only requires one shot. Have feedback? Let us know at [email protected]. First time reading? Sign up here. NEED TO KNOW
Johnson & JohnsonA single-shot vaccine from pharmaceutical giant Johnson & Johnson is safe for use and effective at preventing COVID-19, the US Food and Drug Administration concluded yesterday. The results come ahead of an advisory panel meeting tomorrow to decide whether to recommend emergency use authorization. If approved, the drug would become the third available vaccine in the US. Previous data showed the vaccine to be 72% effective at preventing moderate and severe cases (85% effective when considering just severe cases) of the disease in US trials. Most notably, no deaths were reported in a group of more than 44,000 participants. The vaccine also appears largely effective against the most prominent variants. The vaccine relies on an engineered adenovirus—a weakened form of a relatively harmless virus—to carry snippets of genetic code resembling the coronavirus into cells. Once in, the body's immune system develops a response capable of fighting full-fledged COVID-19 infections. See a great visual breakdown here. The company has said it can deliver up to 20 million doses, which can be stored at standard refrigeration temperatures, by the end of March and 100 million doses by July. The US has reported a total of 505,890 COVID-19 deaths, up roughly 3,230 from yesterday. More than 45 million people have received at least one vaccine dose as of this morning. Cuomo Allegations Lindsey Boylan, an ex-aide to New York Gov. Andrew Cuomo (D), accused her former boss yesterday of multiple instances of sexual harassment ranging over a period of almost three years. The allegations include a 2017 incident in which Boylan says Cuomo suggested playing strip poker aboard a flight, and a separate 2018 incident in which Cuomo kissed her without warning as she tried to leave his office following a one-on-one briefing. Boylan, who initially made the charges in December on Twitter but provided no further detail, laid out the accusations in a Medium post yesterday. Included in the post are emails from Cuomo's senior staff that corroborate parts of Boylan's story. Cuomo's office called the claims false, and the governor previously denied the initial December allegations. The accusations come as Cuomo faces fallout for allegedly obscuring the number of COVID-19 nursing home deaths early in the pandemic. Landmark Syrian ConvictionA German court convicted a former Syrian intelligence officer to more than four years in prison for aiding crimes against humanity in a landmark ruling yesterday. Eyad al-Gharib, 44, was accused of involvement in the arresting of at least 30 anti-government protesters during the 2011 Arab Spring uprising, who were then subject to torture. Gharib fled Syria’s civil war and applied for asylum in Germany, claiming to have defected from President Bashar al-Assad's government. In 2019, he was arrested along with another former officer, Anwar Raslan, under the principle of universal jurisdiction and went on trial in April 2020. The conviction marks the first time a foreign court has ruled on state-sponsored abuses by the Assad regime. Human-rights activists say at least 100,000 people have died from torture or harsh conditions since the conflict began almost 10 years ago. Know someone who needs smart, objective news? Introduce us. WHAT'S AN OPO?
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Sports, Entertainment, & Culture> Officials determine Tiger Woods’ car crash was an accident; Woods was not drinking and no criminal charges will be filed (More) | Here’s how surgeons describe Tiger’s challenging recovery ahead (More) > “Mission: Impossible 7,” “A Quiet Place Part II” among marquee films to be released on new streamer Paramount Plus 45 days after theatrical release (More) > Bruce Springsteen’s drunk and reckless driving charges stemming from November arrest are dropped; Springsteen pleaded guilty to drinking alcohol in a federal park (More) Science & Technology> MIT Technology Review releases its annual forecast of breakthrough technologies for 2021; notable mentions include mRNA vaccines, AI-powered GPT-3 language generator, and the TikTok recommendation algorithms (More) > Study finds exercise facilitates the generation of immune cells in bone marrow (More) > US Air Force demonstrates its Minuteman III intercontinental ballistic missile, hitting a target at a distance of 4,200 miles (More) Business & Markets> US stock markets up (S&P 500 +1.1%, Dow +1.4%, Nasdaq +1.0%); Dow closes at fresh record high after Fed Chairman Jerome Powell reiterates continued support of US economy (More) | Video game retailer GameStop surges 104%, other “meme stocks” also pop (More) > More than 150 CEOs from some of America’s leading companies urge Congress to pass $1.9T stimulus package (More) | House likely to vote tomorrow on Biden administration's $1.9T stimulus package (More) > Joby Aviation—maker of electric, vertical takeoff aircraft—to go public via SPAC at $6.6B valuation (More) Politics & World Affairs> Senate committee delays vote on Neera Tanden's nomination as budget office director; Tanden, the current head of the think tank Center for American Progress, has caught backlash over past tweets (More) > Australia passes scaled-back version of law requiring certain internet companies to pay per link for news articles shared by users on their platforms (More) > Four members of Texas' electric utility board retire in wake of winter storms that paralyzed much of the state's power grid last week (More) | What's behind the $15K energy bills in Texas? (More) IN-DEPTH
Clown PrincesNYT | Dave Itzkoff. Legendary comedians Eddie Murphy and Arsenio Hall discuss what it was like to reunite for "Coming 2 America," the upcoming sequel to their 1988 classic. (Read, $$) The Declassified Story of Juanita MoodySmithsonian | David Wolman. Despite a three-decade, award-winning career as an intelligence officer, Juanita Moody's pivotal role in guiding the US through the Cuban Missile Crisis remained almost entirely unknown for years. (Read) A HIGH-CALIBER INVESTMENT
In partnership with Caliber Please support our sponsors! ETCETERA
The state of Black America in 1900—in historical charts. The secret NASA code on Perseverance's parachute has been cracked. One animation captures two centuries of health and wealth. Witness the rare yellow king penguin. From our partners: This single tool has everything you need to build, host, and market your website or online store. Get started for free. #Ad LGBT identification in America rises to 5.6%. Ready to travel? Here are America's 25 best beaches. Sicily's Mount Etna won't stop erupting. (w/photos) Finally, it's your chance to name a Minnesota snowplow. Clickbait: You won't believe what Chicago ranks No. 1 in. Historybook: Hiram Revels becomes first African American in US Congress (1870); Beatles guitarist George Harrison born (1943); Muhammad Ali, then known as Cassius Clay, defeats Sonny Liston to win his first world heavyweight title (1964); HBD actress Téa Leoni (1966); RIP playwright and poet Tennessee Williams (1983). 
"He who is not courageous enough to take risks will accomplish nothing in life." - Muhammad Ali Enjoy reading? Forward this email to a friend.Why 1440? The printing press was invented in the year 1440, spreading knowledge to the masses and changing the course of history. Guess what else? There are 1,440 minutes in a day and every one is precious. That’s why we scour hundreds of sources every day to provide a concise, comprehensive, and objective view of what's happening in the world. Reader feedback is a gift—shoot us a note at [email protected]. Interested in advertising to smart readers like you? Apply here! 
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Good morning. It's Thursday, Feb. 25, and the US is close to having its third available COVID-19 vaccine—and this one only requires one shot. Have feedback? Let us know at [email protected]. First time reading? Sign up here. NEED TO KNOW
Johnson & JohnsonA single-shot vaccine from pharmaceutical giant Johnson & Johnson is safe for use and effective at preventing COVID-19, the US Food and Drug Administration concluded yesterday. The results come ahead of an advisory panel meeting tomorrow to decide whether to recommend emergency use authorization. If approved, the drug would become the third available vaccine in the US. Previous data showed the vaccine to be 72% effective at preventing moderate and severe cases (85% effective when considering just severe cases) of the disease in US trials. Most notably, no deaths were reported in a group of more than 44,000 participants. The vaccine also appears largely effective against the most prominent variants. The vaccine relies on an engineered adenovirus—a weakened form of a relatively harmless virus—to carry snippets of genetic code resembling the coronavirus into cells. Once in, the body's immune system develops a response capable of fighting full-fledged COVID-19 infections. See a great visual breakdown here. The company has said it can deliver up to 20 million doses, which can be stored at standard refrigeration temperatures, by the end of March and 100 million doses by July. The US has reported a total of 505,890 COVID-19 deaths, up roughly 3,230 from yesterday. More than 45 million people have received at least one vaccine dose as of this morning. Cuomo Allegations Lindsey Boylan, an ex-aide to New York Gov. Andrew Cuomo (D), accused her former boss yesterday of multiple instances of sexual harassment ranging over a period of almost three years. The allegations include a 2017 incident in which Boylan says Cuomo suggested playing strip poker aboard a flight, and a separate 2018 incident in which Cuomo kissed her without warning as she tried to leave his office following a one-on-one briefing. Boylan, who initially made the charges in December on Twitter but provided no further detail, laid out the accusations in a Medium post yesterday. Included in the post are emails from Cuomo's senior staff that corroborate parts of Boylan's story. Cuomo's office called the claims false, and the governor previously denied the initial December allegations. The accusations come as Cuomo faces fallout for allegedly obscuring the number of COVID-19 nursing home deaths early in the pandemic. Landmark Syrian ConvictionA German court convicted a former Syrian intelligence officer to more than four years in prison for aiding crimes against humanity in a landmark ruling yesterday. Eyad al-Gharib, 44, was accused of involvement in the arresting of at least 30 anti-government protesters during the 2011 Arab Spring uprising, who were then subject to torture. Gharib fled Syria’s civil war and applied for asylum in Germany, claiming to have defected from President Bashar al-Assad's government. In 2019, he was arrested along with another former officer, Anwar Raslan, under the principle of universal jurisdiction and went on trial in April 2020. The conviction marks the first time a foreign court has ruled on state-sponsored abuses by the Assad regime. Human-rights activists say at least 100,000 people have died from torture or harsh conditions since the conflict began almost 10 years ago. Know someone who needs smart, objective news? Introduce us. WHAT'S AN OPO?
What do you get when you cross an investment opportunity typically reserved for private equity firms (investing in private companies) with one reserved for the ultrawealthy (real estate)? Please support our sponsors! IN THE KNOW
Sports, Entertainment, & Culture> Officials determine Tiger Woods’ car crash was an accident; Woods was not drinking and no criminal charges will be filed (More) | Here’s how surgeons describe Tiger’s challenging recovery ahead (More) > “Mission: Impossible 7,” “A Quiet Place Part II” among marquee films to be released on new streamer Paramount Plus 45 days after theatrical release (More) > Bruce Springsteen’s drunk and reckless driving charges stemming from November arrest are dropped; Springsteen pleaded guilty to drinking alcohol in a federal park (More) Science & Technology> MIT Technology Review releases its annual forecast of breakthrough technologies for 2021; notable mentions include mRNA vaccines, AI-powered GPT-3 language generator, and the TikTok recommendation algorithms (More) > Study finds exercise facilitates the generation of immune cells in bone marrow (More) > US Air Force demonstrates its Minuteman III intercontinental ballistic missile, hitting a target at a distance of 4,200 miles (More) Business & Markets> US stock markets up (S&P 500 +1.1%, Dow +1.4%, Nasdaq +1.0%); Dow closes at fresh record high after Fed Chairman Jerome Powell reiterates continued support of US economy (More) | Video game retailer GameStop surges 104%, other “meme stocks” also pop (More) > More than 150 CEOs from some of America’s leading companies urge Congress to pass $1.9T stimulus package (More) | House likely to vote tomorrow on Biden administration's $1.9T stimulus package (More) > Joby Aviation—maker of electric, vertical takeoff aircraft—to go public via SPAC at $6.6B valuation (More) Politics & World Affairs> Senate committee delays vote on Neera Tanden's nomination as budget office director; Tanden, the current head of the think tank Center for American Progress, has caught backlash over past tweets (More) > Australia passes scaled-back version of law requiring certain internet companies to pay per link for news articles shared by users on their platforms (More) > Four members of Texas' electric utility board retire in wake of winter storms that paralyzed much of the state's power grid last week (More) | What's behind the $15K energy bills in Texas? (More) IN-DEPTH
Clown PrincesNYT | Dave Itzkoff. Legendary comedians Eddie Murphy and Arsenio Hall discuss what it was like to reunite for "Coming 2 America," the upcoming sequel to their 1988 classic. (Read, $$) The Declassified Story of Juanita MoodySmithsonian | David Wolman. Despite a three-decade, award-winning career as an intelligence officer, Juanita Moody's pivotal role in guiding the US through the Cuban Missile Crisis remained almost entirely unknown for years. (Read) A HIGH-CALIBER INVESTMENT
In partnership with Caliber Please support our sponsors! ETCETERA
The state of Black America in 1900—in historical charts. The secret NASA code on Perseverance's parachute has been cracked. One animation captures two centuries of health and wealth. Witness the rare yellow king penguin. From our partners: This single tool has everything you need to build, host, and market your website or online store. Get started for free. #Ad LGBT identification in America rises to 5.6%. Ready to travel? Here are America's 25 best beaches. Sicily's Mount Etna won't stop erupting. (w/photos) Finally, it's your chance to name a Minnesota snowplow. Clickbait: You won't believe what Chicago ranks No. 1 in. Historybook: Hiram Revels becomes first African American in US Congress (1870); Beatles guitarist George Harrison born (1943); Muhammad Ali, then known as Cassius Clay, defeats Sonny Liston to win his first world heavyweight title (1964); HBD actress Téa Leoni (1966); RIP playwright and poet Tennessee Williams (1983).
"He who is not courageous enough to take risks will accomplish nothing in life." - Muhammad Ali Enjoy reading? Forward this email to a friend.Why 1440? The printing press was invented in the year 1440, spreading knowledge to the masses and changing the course of history. Guess what else? There are 1,440 minutes in a day and every one is precious. That’s why we scour hundreds of sources every day to provide a concise, comprehensive, and objective view of what's happening in the world. Reader feedback is a gift—shoot us a note at [email protected]. Interested in advertising to smart readers like you? Apply here!
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